Enasidenib in IDH2-Mutated Malignant Sinonasal and Skull Base Tumors
Public ClinicalTrials.gov record NCT06176989. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase II Study of Enasidenib in IDH2-mutated Malignant Sinonasal and Skull Base Tumors
Study identification
- NCT ID
- NCT06176989
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- National Cancer Institute (NCI)
- NIH
- Enrollment
- 40 participants
Conditions and interventions
Conditions
- Locally Advanced Chondrosarcoma
- Locally Advanced Large-cell Neuroendocrine Carcinoma
- Locally Advanced Olfactory Neuroblastoma
- Locally Advanced Sinonasal Adenocarcinoma
- Locally Advanced Sinonasal Undifferentiated Carcinoma
- Metastatic Chondrosarcoma
- Metastatic Large-cell Neuroendocrine Carcinoma
- Metastatic Olfactory Neuroblastoma
- Metastatic Sinonasal Adenocarcinoma
- Metastatic Sinonasal Undifferentiated Carcinoma
Interventions
- Enasidenib Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 120 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 3, 2024
- Primary completion
- Dec 30, 2027
- Completion
- Dec 30, 2030
- Last update posted
- Apr 27, 2026
2024 – 2030
United States locations
- U.S. sites
- 1
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| National Institutes of Health Clinical Center | Bethesda | Maryland | 20892 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06176989, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 27, 2026 · Synced May 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06176989 live on ClinicalTrials.gov.