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Completed Phase 3 Interventional Results available

A Clinical Study of the V116 Vaccine for Children and Teenagers (V116-013)

ClinicalTrials.gov ID: NCT06177912

Public ClinicalTrials.gov record NCT06177912. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 3:35 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Randomized, Double-Blind Study to Evaluate the Safety, Tolerability, and Immunogenicity of V116 in Children and Adolescents With Increased Risk of Pneumococcal Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the safety, tolerability, and immunogenicity of V116 compared to PPSV23 in children and teenagers 2 through 17 years of age, who had completed routine pneumococcal vaccine as infants/toddlers. Researchers want to learn if V116 is as good as, or is better than the PPSV23 vaccine in terms of the antibody immune response. V116 and PPSV23 will be studied in children and teenagers who have a higher risk of getting pneumococcal disease (PD).

Study identification

NCT ID
NCT06177912
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Enrollment
882 participants

Conditions and interventions

Interventions

Biological

Eligibility (public fields only)

Age range
2 Years to 17 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 17, 2024
Primary completion
Feb 25, 2025
Completion
Feb 25, 2025
Last update posted
Mar 10, 2026

2024 – 2025

United States locations

U.S. sites
29
U.S. states
17
U.S. cities
26
Facility City State ZIP Site status
Central Research Associates ( Site 0145) Birmingham Alabama 35205
Velocity Clinical Research, Phoenix ( Site 0122) Phoenix Arizona 85006
Madera Family Medical Group ( Site 0120) Madera California 93637
Optumcare Colorado Springs, LLC ( Site 0113) Colorado Springs Colorado 80922
Accel Research Sites Network- Nona Pediatric Center ( Site 0109) Orlando Florida 32829
University of South Florida-Department of Pediatrics ( Site 0110) Tampa Florida 33606
Velocity Clinical Research at Primary Pediatrics, Macon ( Site 0128) Macon Georgia 31210
Bingham Memorial Hospital ( Site 0149) Blackfoot Idaho 83221
Clinical Research Prime ( Site 0105) Idaho Falls Idaho 83404
Clinical Research Prime Rexburg ( Site 0104) Rexburg Idaho 83440
University of Louisville, Norton Children's Research Institute ( Site 0148) Louisville Kentucky 40202
Velocity Clinical Research, Lafayette ( Site 0103) Lafayette Louisiana 70508
Velocity Clinical Research, Gulfport ( Site 0115) Gulfport Mississippi 39503
Velocity Clinical Research, Hastings ( Site 0114) Hastings Nebraska 68901
Midwest Children's Health Research Institute ( Site 0117) Lincoln Nebraska 68504
Midwest Children's Health Research Institute ( Site 0106) Lincoln Nebraska 68505
Midwest Children's Health Research Institute-Research ( Site 0119) Lincoln Nebraska 68516
Midwest Children's Health Research Institute-Research ( Site 0102) Lincoln Nebraska 68522
Velocity Clinical Research, Albuquerque ( Site 0112) Albuquerque New Mexico 87107
Velocity Clinical Research, Vestal ( Site 0121) Vestal New York 13850
Epic Medical Research - Oklahoma ( Site 0134) Chickasha Oklahoma 73018
Tribe Clinical Research, LLC-Pediatrics ( Site 0118) Greenville South Carolina 29607
Tribe Clinical Research - Spartanburg ( Site 0108) Spartanburg South Carolina 29301
Velocity Clinical Research, Austin ( Site 0129) Austin Texas 78759
PanAmerican Clinical Research ( Site 0132) Brownsville Texas 78521
Epic Medical Research ( Site 0133) DeSoto Texas 75115
Epic Medical Research - Mesquite ( Site 0144) Mesquite Texas 75150
Alliance for Multispecialty Research, LLC ( Site 0140) Layton Utah 84041
Velocity Clinical Research, Salt Lake City ( Site 0124) West Jordan Utah 84088

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 63 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06177912, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 10, 2026 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06177912 live on ClinicalTrials.gov.

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