ClinicalTrials.gov record
A Study to Evaluate the Safety, Tolerability, and Immunogenicity of a Combined Modified RNA Vaccine Candidate Against COVID-19 and Influenza.
ClinicalTrials.gov ID: NCT06178991
Public ClinicalTrials.gov record NCT06178991. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 3, RANDOMIZED, OBSERVER-BLINDED STUDY TO EVALUATE THE SAFETY, TOLERABILITY, AND IMMUNOGENICITY OF A COMBINED MODIFIED RNA VACCINE CANDIDATE AGAINST COVID-19 AND INFLUENZA IN HEALTHY INDIVIDUALS
Study identification
- NCT ID
- NCT06178991
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- BioNTech SE
- Industry
- Enrollment
- 8,795 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 64 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 19, 2023
- Primary completion
- Nov 25, 2024
- Completion
- Nov 25, 2024
- Last update posted
- Dec 3, 2025
2023 – 2024
United States locations
- U.S. sites
- 106
- U.S. states
- 27
- U.S. cities
- 79
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| North Alabama Research Center | Athens | Alabama | 35611 | — |
| Accel Research Sites - Birmingham Clinical Research Unit | Birmingham | Alabama | 35216 | — |
| AMR Clinical | Mobile | Alabama | 36608 | — |
| HOPE Research Institute | Phoenix | Arizona | 85032 | — |
| Foothills Research Center/ CCT Research | Phoenix | Arizona | 85044 | — |
| Scottsdale Clinical Trials | Scottsdale | Arizona | 85260 | — |
| Alliance for Multispecialty Research, LLC | Tempe | Arizona | 85281 | — |
| Baptist Health Center For Clinical Research | Little Rock | Arkansas | 72205 | — |
| Hope Clinical Research, Inc. | Canoga Park | California | 91303 | — |
| Ascada Health PC dba Ascada Research | Fullerton | California | 92835 | — |
| Orange County Research Center | Lake Forest | California | 92630 | — |
| Ark Clinical Research | Long Beach | California | 90815 | — |
| Collaborative Neuroscience Research, LLC | Los Alamitos | California | 90720 | — |
| Artemis Institute for Clinical Research | San Diego | California | 92103 | — |
| Acclaim Clinical Research | San Diego | California | 92120 | — |
| Bayview Research Group, LLC | Valley Village | California | 91607 | — |
| Synexus Clinical Research US, Inc. | Vista | California | 92083 | — |
| Diablo Clinical Research, Inc. | Walnut Creek | California | 94598 | — |
| Tampa Bay Medical Research | Clearwater | Florida | 33761 | — |
| Universal Axon Clinical Research, LLC | Doral | Florida | 33166 | — |
| Proactive Clinical Research,LLC | Fort Lauderdale | Florida | 33308 | — |
| Finlay Medical Research | Greenacres City | Florida | 33467 | — |
| Indago Research & Health Center, Inc | Hialeah | Florida | 33012 | — |
| Best Quality Research,Inc. | Hialeah | Florida | 33016 | — |
| Clinical Neuroscience Solutions, Inc. dba CNS Healthcare | Jacksonville | Florida | 32256 | — |
| Miami Clinical Research | Miami | Florida | 33155 | — |
| Gerardo Polanco, MD | Miami | Florida | 33156 | — |
| Research Institute of South Florida | Miami | Florida | 33173 | — |
| Entrust Clinical Research | Miami | Florida | 33176 | — |
| Miami Dade Medical Research Institute, LLC | Miami | Florida | 33176 | — |
| Clinical Site Partners LLC, dba Flourish Research | Miami | Florida | 33186 | — |
| Palm Springs Community Health Center | Miami Lakes | Florida | 33014 | — |
| Angels Clinical Research Institute | Miami Lakes | Florida | 33016 | — |
| Clinical Neuroscience Solutions, Inc. | Orlando | Florida | 32801 | — |
| Innovation Medical Research Center | Palmetto Bay | Florida | 33157 | — |
| DBC Research USA | Pembroke Pines | Florida | 33029 | — |
| Angels Clinical Research Institute | Tampa | Florida | 33614 | — |
| Centricity Research Columbus Georgia Multispecialty | Columbus | Georgia | 31904 | — |
| AGILE Clinical Research Trials, LLC | Sandy Springs | Georgia | 30328 | — |
| Clinical Research Atlanta | Stockbridge | Georgia | 30281 | — |
| East-West Medical Research Institute | Honolulu | Hawaii | 96814 | — |
| Clinical Research Prime | Idaho Falls | Idaho | 83404 | — |
| Velocity Clinical Research, Boise | Meridian | Idaho | 83642 | — |
| Solaris Clinical Research | Meridian | Idaho | 83646 | — |
| Synexus Clinical Research US, Inc. | Chicago | Illinois | 60602 | — |
| Great Lakes Clinical Trials - Ravenswood | Chicago | Illinois | 60640 | — |
| Koch Family Medicine | Morton | Illinois | 61550 | — |
| Velocity Clinical Research, Sioux City | Sioux City | Iowa | 51106 | — |
| AMR Clinical | Wichita | Kansas | 67207 | — |
| Pharmaron | Baltimore | Maryland | 21201 | — |
| Jadestone Clinical Research | Silver Spring | Maryland | 20904 | — |
| Headlands Research - Detroit | Southfield | Michigan | 48034 | — |
| Revival Research Institute, LLC | Sterling Heights | Michigan | 48312 | — |
| Clinical Research Professionals | Chesterfield | Missouri | 63005 | — |
| Alliance for Multispecialty Research, LLC | Kansas City | Missouri | 64114 | — |
| Saint Louis University Center for Vaccine Development | St Louis | Missouri | 63104 | — |
| Sundance Clinical Research | St Louis | Missouri | 63141 | — |
| Velocity Clinical Research, Grand Island | Grand Island | Nebraska | 68803 | — |
| Quality Clinical Research | Omaha | Nebraska | 68114 | — |
| Velocity Clinical Research, Omaha | Omaha | Nebraska | 68134 | — |
| McGill Family Practice | Papillion | Nebraska | 68046 | — |
| Las Vegas Clinical Trials | North Las Vegas | Nevada | 89030 | — |
| IMA Clinical Research Warren | Warren Township | New Jersey | 07059 | — |
| Rochester Clinical Research, LLC | Rochester | New York | 14609 | — |
| Duke Vaccine and Trials Unit | Durham | North Carolina | 27703 | — |
| Accellacare - Hickory | Hickory | North Carolina | 28601 | — |
| Monroe Biomedical Research | Monroe | North Carolina | 28112 | — |
| M3 Wake Research, Inc. | Raleigh | North Carolina | 27612 | — |
| Accellacare - Rocky Mount | Rocky Mount | North Carolina | 27804 | — |
| Accellacare - Wilmington | Wilmington | North Carolina | 28401 | — |
| Trial Management Associates - Wilmington - Floral Parkway | Wilmington | North Carolina | 28403 | — |
| Trial Management Associates, LLC | Wilmington | North Carolina | 28403 | — |
| Accellacare - Winston-Salem | Winston-Salem | North Carolina | 27103 | — |
| CTI Clinical Research Center | Cincinnati | Ohio | 45212 | — |
| Velocity Clinical Research, Cincinnati, Mt. Auburn | Cincinnati | Ohio | 45219 | — |
| Synexus Clinical Research US, Inc. | Cincinnati | Ohio | 45236 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| Velocity Clinical Research, Medford | Medford | Oregon | 97504 | — |
| Trial Management Associates, LLC | Myrtle Beach | South Carolina | 29572 | — |
| Trial Management Associates | Myrtle Beach | South Carolina | 29572 | — |
| Internal Medicine and Pediatric Associates of Bristol | Bristol | Tennessee | 37620 | — |
| Alliance for Multispecialty Research, LLC | Knoxville | Tennessee | 37909 | — |
| New Phase Research and Development | Knoxville | Tennessee | 37909 | — |
| Alliance for Multispecialty Research, LLC | Knoxville | Tennessee | 37920 | — |
| Clinical Neuroscience Solutions Inc. | Memphis | Tennessee | 38119 | — |
| Benchmark Research | Austin | Texas | 78705 | — |
| Tekton Research, LLC. | Austin | Texas | 78745 | — |
| Orion Clinical Research | Austin | Texas | 78759 | — |
| Headlands Horizons, LLC dba Headlands Research-Brownsville | Brownsville | Texas | 78526 | — |
| DFW Clinical Research | Dallas | Texas | 75240 | — |
| Benchmark Research | Fort Worth | Texas | 76135 | — |
| Texas Health Family Care | Fort Worth | Texas | 76135 | — |
| Santa Clara Family Clinic | Houston | Texas | 77087 | — |
| SMS Clinical Research | Mesquite | Texas | 75149 | — |
| ACRC Trials (Administrative Location) | Plano | Texas | 75024 | — |
| ACRC TRIALS / North Texas Family Medicine | Plano | Texas | 75093 | — |
| AIM Trials, LLC | Plano | Texas | 75093 | — |
| Clinical Trials of Texas, LLC dba Flourish Research | San Antonio | Texas | 78229 | — |
| IMA Clinical Research San Antonio | San Antonio | Texas | 78229 | — |
| DM Clinical Research, Martin Diagnostic Clinic | Tomball | Texas | 77375 | — |
| Northwest Houston Heart Center | Tomball | Texas | 77375 | — |
| AMR Clinical | Layton | Utah | 84041 | — |
| J. Lewis Research, Inc. / Foothill Family Clinic South | Salt Lake City | Utah | 84121 | — |
| Velocity Clinical Research, Salt Lake City | West Jordan | Utah | 84088 | — |
| Health Research of Hampton Roads, Inc. | Newport News | Virginia | 23606 | — |
| AMR Clinical | Norfolk | Virginia | 23502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06178991, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 3, 2025 · Synced Apr 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06178991 live on ClinicalTrials.gov.