Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1
Public ClinicalTrials.gov record NCT06188741. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 2 Trial of Selumetinib for the Prevention of Plexiform Neurofibroma Growth and Morbidity in Neurofibromatosis Type 1
Study identification
- NCT ID
- NCT06188741
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Enrollment
- 200 participants
Conditions and interventions
Conditions
Interventions
- Selumetinib Drug
Drug
Eligibility (public fields only)
- Age range
- 1 Year to 8 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 26, 2025
- Primary completion
- Aug 31, 2031
- Completion
- Aug 31, 2032
- Last update posted
- May 28, 2026
2025 – 2032
United States locations
- U.S. sites
- 15
- U.S. states
- 12
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Childrens of Alabama | Birmingham | Alabama | 35233 | Recruiting |
| Children's Hospital of Los Angeles | Los Angeles | California | 90027 | Recruiting |
| Stanford University | Palo Alto | California | 94304 | Recruiting |
| Children's National Hospital | Washington D.C. | District of Columbia | 20010 | Recruiting |
| Lurie Children's Hospital of Chicago | Chicago | Illinois | 60611 | Recruiting |
| University of Chicago | Chicago | Illinois | 63637 | Recruiting |
| Riley Hospital for Children/Indiana University | Indianapolis | Indiana | 46202 | Recruiting |
| Johns Hopkins University | Baltimore | Maryland | 21231 | Recruiting |
| National Cancer Institute/ National Institutes of Health | Bethesda | Maryland | 20892 | Recruiting |
| Boston Children's Hospital | Boston | Massachusetts | 02115 | Recruiting |
| Mayo Clinic | Rochester | Minnesota | 55905 | Recruiting |
| Washington University - St. Louis | St Louis | Missouri | 63110 | Recruiting |
| Cincinnati Childrens Hospital Medical Center | Cincinnati | Ohio | 45229- | Recruiting |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | Recruiting |
| University of Texas, Southwestern | Dallas | Texas | 75390 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06188741, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 28, 2026 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06188741 live on ClinicalTrials.gov.