Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II)

ClinicalTrials.gov ID: NCT06192615

Public ClinicalTrials.gov record NCT06192615. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Jul 24, 2026, 9:15 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Study identification

NCT ID: NCT06192615
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Massachusetts General Hospital; Other
Enrollment: 1,800 participants

Conditions and interventions

Conditions

Delirium

Interventions

Intravenous Dexmedetomidine Drug
Sublingual Dexmedetomidine Drug
Intravenous Placebo Drug
Sublingual Placebo Drug

Drug

Eligibility (public fields only)

Age range: 60 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jan 5, 2025
Primary completion: Oct 30, 2027
Completion: Mar 30, 2029
Last update posted: Jul 5, 2026

2025 – 2029

United States locations

U.S. sites: 14
U.S. states: 10
U.S. cities: 12

Facility	City	State	ZIP	Site status
Cedars-Sinai Medical Center	Los Angeles	California	90048	Not yet recruiting
University of California San Francisco	San Francisco	California	94117	Not yet recruiting
Northwestern University Feinberg School of Medicine	Chicago	Illinois	60611	Recruiting
University of Iowa Carver College of Medicine	Iowa City	Iowa	522421320	Recruiting
University of Maryland School of Medicine	Baltimore	Maryland	21201	Recruiting
Massachusetts General Hospital	Boston	Massachusetts	02114	Recruiting
Beth Israel Deaconess Medical Center	Boston	Massachusetts	02215	Recruiting
Brigham and Women's Hospital	Boston	Massachusetts	02215	Recruiting
Washington University School of Medicine	St Louis	Missouri	63110	Not yet recruiting
University of Nebraska Medical Center	Omaha	Nebraska	68198	Recruiting
Columbia University Medical Center	New York	New York	10032	Recruiting
Montefiore Medical Center	The Bronx	New York	10467	Not yet recruiting
Duke University Hospital	Durham	North Carolina	27710	Recruiting
Vanderbilt University Medical Center	Nashville	Tennessee	37232	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06192615, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jul 5, 2026 · Synced Jul 24, 2026

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The complete protocol, eligibility criteria, and contact information for NCT06192615 live on ClinicalTrials.gov.

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