A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALIANT)
Public ClinicalTrials.gov record NCT06196879. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-blind, Placebo-controlled, Multi-center, Dose-ranging Study to Evaluate the Efficacy and Safety of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALIANT)
Study identification
- NCT ID
- NCT06196879
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Upstream Bio Inc.
- Industry
- Enrollment
- 479 participants
Conditions and interventions
Conditions
Not listed
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 26, 2024
- Primary completion
- Dec 15, 2025
- Completion
- Mar 18, 2026
- Last update posted
- Apr 30, 2026
2024 – 2026
United States locations
- U.S. sites
- 55
- U.S. states
- 21
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| AllerVie Clinical Research | Birmingham | Alabama | 35209 | — |
| Kern Research, Inc. | Bakersfield | California | 93301 | — |
| Velocity Clinical Research - Lafayette LA | Los Angeles | California | 70508 | — |
| Newport Native MD Inc | Newport Beach | California | 92663 | — |
| California Medical Research Associates Inc. | Northridge | California | 91324 | — |
| Integrated Research of Inland Inc | Upland | California | 91786 | — |
| Allergy & Asthma Clinical Research | Walnut Creek | California | 94598 | — |
| Allianz Research Institute | Westminster | California | 92683 | — |
| Woodland Clinic Medical Group | Woodland | California | 95695 | — |
| National Jewish Health | Denver | Colorado | 80206 | — |
| Advance Pharma Research | Cutler Bay | Florida | 33189 | — |
| Unique Clinical Trials | Doral | Florida | 33172 | — |
| Health and Life Research Institute, LLC | Miami | Florida | 33155 | — |
| Phoenix Medical Research | Miami | Florida | 33165 | — |
| Research Institute of South Florida | Miami | Florida | 33173 | — |
| Nouvelle Clinical Research | Miami | Florida | 33189 | — |
| Anderson Allergy And Asthma, PA | Orlando | Florida | 32806 | — |
| Edward Jenner Research Group, LLC | Plantation | Florida | 33317 | — |
| R&B Medical Center | Tampa | Florida | 33614 | — |
| Clinical Site Partners dba Flourish research | Winter Park | Florida | 32789 | — |
| Clinical Site Partners, LLC dba Flourish Research | Winter Park | Florida | 32789 | — |
| Pivotal Research Solutions | Stonecrest | Georgia | 30038 | — |
| RNA America Health Sciences | Sugar Hill | Georgia | 30518 | — |
| Treasure Valley Medical Research | Boise | Idaho | 83706 | — |
| Velocity Clinical Research - Meridian | Meridian | Idaho | 83642 | — |
| Howard County Center for Lung and Sleep Medicine LLC | Columbia | Maryland | 21044 | — |
| Chesapeake Clinical Research Inc | White Marsh | Maryland | 21162 | — |
| Exordia Medical Research Inc | Fall River | Massachusetts | 02723 | — |
| Pulmonary Research Institute of Southeast Michigan | Farmington Hills | Michigan | 48336 | — |
| AA Medical Research Center | Flint | Michigan | 48504 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| M3 Wake Research | Las Vegas | Nevada | 89106 | — |
| Urban Health Plan INC | The Bronx | New York | 10459 | — |
| Advanced Respiratory and Sleep Medicine LLC | Huntersville | North Carolina | 28078 | — |
| Summit Research Group LLC | Munroe Falls | Ohio | 44262 | — |
| Toledo Institute of Clinical Research Inc | Toledo | Ohio | 43617 | — |
| OK Clinical Research, LLC | Edmond | Oklahoma | 73034 | — |
| Portland Clinical Research | Clackamas | Oregon | 97015 | — |
| Velocity Clinical Research - Medford | Medford | Oregon | 97504 | — |
| Velocity Clinical Research - Anderson | Anderson | South Carolina | 29621 | — |
| WR-Notus Clinical Research, LLC | Charleston | South Carolina | 29414 | — |
| Velocity Clinical Research - Spartanburg | Spartanburg | South Carolina | 29303 | — |
| WR-ClinSearch, LLC | Chattanooga | Tennessee | 37421 | — |
| Horizon Clinical Research | Cypress | Texas | 77429 | — |
| Alina Clinical Trials, LLC | Dallas | Texas | 75225 | — |
| AARA Research Center | Dallas | Texas | 75231 | — |
| El Paso Pulmonary Association | El Paso | Texas | 79902 | — |
| Greater Houston Memorial Pulmonary and Sleep | Houston | Texas | 77008 | — |
| Sante Clinical Research | Kerrville | Texas | 78028 | — |
| Mayflower Clinical | Marble Falls | Texas | 02747 | — |
| Metroplex Pulmonary and Sleep Center Drive | McKinney | Texas | 75069 | — |
| Element Research Group | San Antonio | Texas | 78258 | — |
| DM Clinical Tomball | Tomball | Texas | 77375 | — |
| Velocity Clinical Research | West Jordan | Utah | 84088 | — |
| University of Wisconsin--Madison | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 73 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06196879, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 30, 2026 · Synced May 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06196879 live on ClinicalTrials.gov.