ClinicalTrials.gov record
Developing an Internet-Delivered Sexual Health Program for Breast Cancer Survivors, SHINE Trial
ClinicalTrials.gov ID: NCT06216574
Public ClinicalTrials.gov record NCT06216574. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Optimizing Psychosocial Intervention for Breast Cancer-Related Sexual Morbidity:The Sexual Health and Intimacy Education (SHINE) Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The goal of this clinical trial is to develop an effective internet-delivered program to help breast cancer survivors manage cancer-related sexual concerns. This study is being done to find out if the study approach is better or worse than the usual approach to helping breast cancer survivors manage cancer-related sexual concerns. The usual approach is defined as care most cancer survivors get for their cancer-related sexual concerns. Participants will complete a questionnaire and if they qualify, they will be assigned to one of sixteen groups of participants. Groups will get access to various kinds of help through an Internet-delivered program called SHINE, which was designed and is run by researchers at the University of Virginia Center for Behavioral Health and Technology. All groups will get access to education about sexual health after cancer: either a standard education website or an enhanced education web program. Groups may also receive up to three additional web programs on: talking to your clinicians about sexual concerns, and/or talking to your partner about sexual concerns, and/or increasing intimacy. Participants are asked to complete the SHINE program within 12 weeks. After participants finish this 12-week period, the study team will ask them to complete a questionnaire to check in with the participant. The participant will be asked one additional time 12 weeks later to complete another questionnaire to see how the participant is doing. A participant will be in the study for 24 weeks.
Study identification
- NCT ID
- NCT06216574
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 340 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 14, 2024 (Actual)
- Primary completion
- Aug 1, 2027 (Estimated)
- Completion
- Aug 1, 2027 (Estimated)
- Last update posted
- Feb 18, 2026
2024 – 2027
United States locations
- U.S. sites
- 236
- U.S. states
- 30
- U.S. cities
- 202
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cancer Center at Saint Joseph's | Phoenix | Arizona | 85004 | — |
| Mercy Hospital Fort Smith | Fort Smith | Arkansas | 72903 | — |
| Kaiser Permanente-Deer Valley Medical Center | Antioch | California | 94531 | — |
| Kaiser Permanente Dublin | Dublin | California | 94568 | — |
| Kaiser Permanente-Fremont | Fremont | California | 94538 | — |
| Kaiser Permanente-Fresno | Fresno | California | 93720 | — |
| Kaiser Permanente-Modesto | Modesto | California | 95356 | — |
| Kaiser Permanente-Oakland | Oakland | California | 94611 | — |
| Kaiser Permanente- Marshall Medical Offices | Redwood City | California | 94063 | — |
| Kaiser Permanente-Richmond | Richmond | California | 94801 | — |
| Kaiser Permanente-Roseville | Roseville | California | 95661 | — |
| Kaiser Permanente Downtown Commons | Sacramento | California | 95814 | — |
| Kaiser Permanente-South Sacramento | Sacramento | California | 95823 | — |
| Kaiser Permanente-San Francisco | San Francisco | California | 94115 | — |
| Kaiser Permanente-Santa Teresa-San Jose | San Jose | California | 95119 | — |
| Kaiser Permanente San Leandro | San Leandro | California | 94577 | — |
| Kaiser San Rafael-Gallinas | San Rafael | California | 94903 | — |
| Kaiser Permanente Medical Center - Santa Clara | Santa Clara | California | 95051 | — |
| Kaiser Permanente-Santa Rosa | Santa Rosa | California | 95403 | — |
| Providence Medical Foundation - Santa Rosa | Santa Rosa | California | 95403 | — |
| Providence Santa Rosa Memorial Hospital | Santa Rosa | California | 95405 | — |
| Kaiser Permanente-South San Francisco | South San Francisco | California | 94080 | — |
| Kaiser Permanente-Stockton | Stockton | California | 95210 | — |
| Kaiser Permanente Medical Center-Vacaville | Vacaville | California | 95688 | — |
| Kaiser Permanente-Vallejo | Vallejo | California | 94589 | — |
| Kaiser Permanente-Walnut Creek | Walnut Creek | California | 94596 | — |
| Beebe South Coastal Health Campus | Frankford | Delaware | 19945 | — |
| Helen F Graham Cancer Center | Newark | Delaware | 19713 | — |
| Medical Oncology Hematology Consultants PA | Newark | Delaware | 19713 | — |
| Beebe Health Campus | Rehoboth Beach | Delaware | 19971 | — |
| MedStar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| MedStar Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Atrium Health Navicent | Macon | Georgia | 31201 | — |
| Memorial Health University Medical Center | Savannah | Georgia | 31404 | — |
| Kaiser Permanente Moanalua Medical Center | Honolulu | Hawaii | 96819 | — |
| Rush-Copley Medical Center | Aurora | Illinois | 60504 | — |
| Advocate Outpatient Center - Aurora | Aurora | Illinois | 60506 | — |
| Advocate Good Shepherd Hospital | Barrington | Illinois | 60010 | — |
| Illinois CancerCare-Bloomington | Bloomington | Illinois | 61704 | — |
| Illinois CancerCare-Canton | Canton | Illinois | 61520 | — |
| Illinois CancerCare-Carthage | Carthage | Illinois | 62321 | — |
| Advocate Illinois Masonic Medical Center | Chicago | Illinois | 60657 | — |
| AMG Crystal Lake - Oncology | Crystal Lake | Illinois | 60014 | — |
| Carle at The Riverfront | Danville | Illinois | 61832 | — |
| Cancer Care Specialists of Illinois - Decatur | Decatur | Illinois | 62526 | — |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| Advocate Good Samaritan Hospital | Downers Grove | Illinois | 60515 | — |
| Carle Physician Group-Effingham | Effingham | Illinois | 62401 | — |
| Crossroads Cancer Center | Effingham | Illinois | 62401 | — |
| Advocate Sherman Hospital | Elgin | Illinois | 60123 | — |
| Illinois CancerCare-Eureka | Eureka | Illinois | 61530 | — |
| Illinois CancerCare-Galesburg | Galesburg | Illinois | 61401 | — |
| Advocate South Suburban Hospital | Hazel Crest | Illinois | 60429 | — |
| Illinois CancerCare-Kewanee Clinic | Kewanee | Illinois | 61443 | — |
| AMG Libertyville - Oncology | Libertyville | Illinois | 60048 | — |
| Condell Memorial Hospital | Libertyville | Illinois | 60048 | — |
| Illinois CancerCare-Macomb | Macomb | Illinois | 61455 | — |
| Carle Physician Group-Mattoon/Charleston | Mattoon | Illinois | 61938 | — |
| Cancer Care Center of O'Fallon | O'Fallon | Illinois | 62269 | — |
| Advocate Christ Medical Center | Oak Lawn | Illinois | 60453-2699 | — |
| Illinois CancerCare-Ottawa Clinic | Ottawa | Illinois | 61350 | — |
| Advocate Lutheran General Hospital | Park Ridge | Illinois | 60068 | — |
| Illinois CancerCare-Pekin | Pekin | Illinois | 61554 | — |
| Illinois CancerCare-Peoria | Peoria | Illinois | 61615 | — |
| Illinois CancerCare-Peru | Peru | Illinois | 61354 | — |
| Illinois CancerCare-Princeton | Princeton | Illinois | 61356 | — |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62702 | — |
| Springfield Clinic | Springfield | Illinois | 62702 | — |
| Springfield Memorial Hospital | Springfield | Illinois | 62781 | — |
| Carle Cancer Center | Urbana | Illinois | 61801 | — |
| Illinois CancerCare - Washington | Washington | Illinois | 61571 | — |
| Rush-Copley Healthcare Center | Yorkville | Illinois | 60560 | — |
| The University of Iowa - Ankeny | Ankeny | Iowa | 50023 | — |
| Saint Anthony Regional Hospital | Carroll | Iowa | 51401 | — |
| Physicians' Clinic of Iowa PC | Cedar Rapids | Iowa | 52402 | — |
| Oncology Associates at Mercy Medical Center | Cedar Rapids | Iowa | 52403 | — |
| Mercy Cancer Center-West Lakes | Clive | Iowa | 50325 | — |
| The University of Iowa - West De Moines | Clive | Iowa | 50325 | — |
| Iowa Methodist Medical Center | Des Moines | Iowa | 50309 | — |
| The University of Iowa - Des Moines | Des Moines | Iowa | 50309 | — |
| Broadlawns Medical Center | Des Moines | Iowa | 50314 | — |
| Mercy Medical Center - Des Moines | Des Moines | Iowa | 50314 | — |
| The University of Iowa - Laurel | Des Moines | Iowa | 50314 | — |
| Trinity Regional Medical Center | Fort Dodge | Iowa | 50501 | — |
| Saint Joseph Hospital East | Lexington | Kentucky | 40509 | — |
| Louisiana State University Health Science Center | New Orleans | Louisiana | 70112 | — |
| University Medical Center New Orleans | New Orleans | Louisiana | 70112 | — |
| Harold Alfond Center for Cancer Care | Augusta | Maine | 04330 | — |
| MaineHealth/SMHC Cancer Care and Blood Disorders-Biddeford | Biddeford | Maine | 04005 | — |
| Penobscot Bay Medical Center | Rockport | Maine | 04856 | — |
| MaineHealth/SMHC Cancer Care and Blood Disorders-Sanford | Sanford | Maine | 04073 | — |
| Maine Medical Center- Scarborough Campus | Scarborough | Maine | 04074 | — |
| Maine Medical Partners - South Portland | South Portland | Maine | 04106 | — |
| Christiana Care - Union Hospital | Elkton | Maryland | 21921 | — |
| Trinity Health IHA Medical Group Hematology Oncology - Brighton | Brighton | Michigan | 48114 | — |
| Trinity Health IHA Medical Group Hematology Oncology - Canton | Canton | Michigan | 48188 | — |
| Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital | Chelsea | Michigan | 48118 | — |
| Genesee Cancer and Blood Disease Treatment Center | Flint | Michigan | 48503 | — |
| Genesee Hematology Oncology PC | Flint | Michigan | 48503 | — |
| Genesys Hurley Cancer Institute | Flint | Michigan | 48503 | — |
| Trinity Health Saint Mary Mercy Livonia Hospital | Livonia | Michigan | 48154 | — |
| Trinity Health Saint Joseph Mercy Oakland Hospital | Pontiac | Michigan | 48341 | — |
| Ascension Saint Mary's Hospital | Saginaw | Michigan | 48601 | — |
| University of Michigan Health - West | Wyoming | Michigan | 49519 | — |
| Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus | Ypsilanti | Michigan | 48197 | — |
| Essentia Health - Baxter Clinic | Baxter | Minnesota | 56425 | — |
| Sanford Joe Lueken Cancer Center | Bemidji | Minnesota | 56601 | — |
| Essentia Health Saint Joseph's Medical Center | Brainerd | Minnesota | 56401 | — |
| Minnesota Oncology - Burnsville | Burnsville | Minnesota | 55337 | — |
| Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| Essentia Health - Deer River Clinic | Deer River | Minnesota | 56636 | — |
| Essentia Health Saint Mary's - Detroit Lakes Clinic | Detroit Lakes | Minnesota | 56501 | — |
| Essentia Health Cancer Center | Duluth | Minnesota | 55805 | — |
| Fairview Southdale Hospital | Edina | Minnesota | 55435 | — |
| Essentia Health - Ely Clinic | Ely | Minnesota | 55731 | — |
| Essentia Health - Fosston | Fosston | Minnesota | 56542 | — |
| Essentia Health Hibbing Clinic | Hibbing | Minnesota | 55746 | — |
| Essentia Health - International Falls Clinic | International Falls | Minnesota | 56649 | — |
| Fairview Clinics and Surgery Center Maple Grove | Maple Grove | Minnesota | 55369 | — |
| Minnesota Oncology Hematology PA-Maplewood | Maplewood | Minnesota | 55109 | — |
| Saint John's Hospital - Healtheast | Maplewood | Minnesota | 55109 | — |
| Abbott-Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55415 | — |
| Monticello Cancer Center | Monticello | Minnesota | 55362 | — |
| New Ulm Medical Center | New Ulm | Minnesota | 56073 | — |
| Essentia Health - Park Rapids | Park Rapids | Minnesota | 56470 | — |
| North Memorial Medical Health Center | Robbinsdale | Minnesota | 55422 | — |
| Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | 55416 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| United Hospital | Saint Paul | Minnesota | 55102 | — |
| Saint Francis Regional Medical Center | Shakopee | Minnesota | 55379 | — |
| Essentia Health Virginia Clinic | Virginia | Minnesota | 55792 | — |
| Ridgeview Medical Center | Waconia | Minnesota | 55387 | — |
| Rice Memorial Hospital | Willmar | Minnesota | 56201 | — |
| Minnesota Oncology Hematology PA-Woodbury | Woodbury | Minnesota | 55125 | — |
| Fairview Lakes Medical Center | Wyoming | Minnesota | 55092 | — |
| Baptist Memorial Hospital and Cancer Center-Oxford | Oxford | Mississippi | 38655 | — |
| Saint Louis Cancer and Breast Institute-Ballwin | Ballwin | Missouri | 63011 | — |
| Mercy Hospital Joplin | Joplin | Missouri | 64804 | — |
| Lake Regional Hospital | Osage Beach | Missouri | 65065 | — |
| Mercy Clinic-Rolla-Cancer and Hematology | Rolla | Missouri | 65401 | — |
| Mercy Hospital Springfield | Springfield | Missouri | 65804 | — |
| Mercy Hospital South | St Louis | Missouri | 63128 | — |
| Mercy Hospital Saint Louis | St Louis | Missouri | 63141 | — |
| CHI Health Good Samaritan | Kearney | Nebraska | 68847 | — |
| OptumCare Cancer Care at Seven Hills | Henderson | Nevada | 89052 | — |
| OptumCare Cancer Care at Charleston | Las Vegas | Nevada | 89102 | — |
| OptumCare Cancer Care at Fort Apache | Las Vegas | Nevada | 89148 | — |
| CentraState Medical Center | Freehold | New Jersey | 07728 | — |
| Hackettstown Medical Center | Hackettstown | New Jersey | 07840 | — |
| Morristown Medical Center | Morristown | New Jersey | 07960 | — |
| Newton Medical Center | Newton | New Jersey | 07860 | — |
| Capital Health Medical Center-Hopewell | Pennington | New Jersey | 08534 | — |
| Chilton Medical Center | Pompton | New Jersey | 07444 | — |
| Overlook Medical Center | Summit | New Jersey | 07901 | — |
| Holy Name Hospital | Teaneck | New Jersey | 07666 | — |
| Randolph Health Cancer Center | Asheboro | North Carolina | 27203 | — |
| Cone Health Cancer Center at Alamance Regional | Burlington | North Carolina | 27215 | — |
| Cone Health Cancer Center | Greensboro | North Carolina | 27403 | — |
| Cone Health Cancer Center at Drawbridge Parkway | Greensboro | North Carolina | 27410 | — |
| Annie Penn Memorial Hospital | Reidsville | North Carolina | 27320 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Sanford Bismarck Medical Center | Bismarck | North Dakota | 58501 | — |
| Essentia Health Cancer Center-South University Clinic | Fargo | North Dakota | 58103 | — |
| Sanford Broadway Medical Center | Fargo | North Dakota | 58122 | — |
| Sanford Roger Maris Cancer Center | Fargo | North Dakota | 58122 | — |
| Good Samaritan Hospital - Cincinnati | Cincinnati | Ohio | 45220 | — |
| Mount Carmel East Hospital | Columbus | Ohio | 43213 | — |
| The Mark H Zangmeister Center | Columbus | Ohio | 43219 | — |
| Central Ohio Breast and Endocrine Surgery | Gahanna | Ohio | 43230 | — |
| Mount Carmel Grove City Hospital | Grove City | Ohio | 43123 | — |
| Saint Ann's Hospital | Westerville | Ohio | 43081 | — |
| Mercy Hospital Oklahoma City | Oklahoma City | Oklahoma | 73120 | — |
| Saint Charles Health System | Bend | Oregon | 97701 | — |
| Providence Newberg Medical Center | Newberg | Oregon | 97132 | — |
| Providence Willamette Falls Medical Center | Oregon City | Oregon | 97045 | — |
| Providence Portland Medical Center | Portland | Oregon | 97213 | — |
| Providence Saint Vincent Medical Center | Portland | Oregon | 97225 | — |
| Saint Charles Health System-Redmond | Redmond | Oregon | 97756 | — |
| AnMed Health Cancer Center | Anderson | South Carolina | 29621 | — |
| Beaufort Memorial Hospital | Beaufort | South Carolina | 29902 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Gibbs Cancer Center-Gaffney | Gaffney | South Carolina | 29341 | — |
| Self Regional Healthcare | Greenwood | South Carolina | 29646 | — |
| Gibbs Cancer Center-Pelham | Greer | South Carolina | 29651 | — |
| Beaufort Memorial/New River Cancer Center | Okatie | South Carolina | 29909 | — |
| Spartanburg Medical Center | Spartanburg | South Carolina | 29303 | — |
| SMC Center for Hematology Oncology-Union | Union | South Carolina | 29379 | — |
| Lexington Medical Center | West Columbia | South Carolina | 29169 | — |
| Baptist Memorial Hospital and Cancer Center-Collierville | Collierville | Tennessee | 38017 | — |
| Baptist Memorial Hospital and Cancer Center-Memphis | Memphis | Tennessee | 38120 | — |
| Baptist Memorial Hospital for Women | Memphis | Tennessee | 38120 | — |
| Chesapeake Regional Medical Center | Chesapeake | Virginia | 23320 | — |
| Virginia Commonwealth University/Massey Cancer Center | Richmond | Virginia | 23298 | — |
| Shenandoah Oncology PC | Winchester | Virginia | 22601 | — |
| Kaiser Permanente Bellevue Medical Center | Bellevue | Washington | 98004 | — |
| PeaceHealth Saint Joseph Medical Center | Bellingham | Washington | 98225 | — |
| Kadlec Clinic Hematology and Oncology | Kennewick | Washington | 99336 | — |
| Kaiser Permanente Washington | Seattle | Washington | 98112 | — |
| PeaceHealth United General Medical Center | Sedro-Woolley | Washington | 98284 | — |
| Providence Saint Mary Regional Cancer Center | Walla Walla | Washington | 99362 | — |
| ThedaCare Regional Cancer Center | Appleton | Wisconsin | 54911 | — |
| Duluth Clinic Ashland | Ashland | Wisconsin | 54806 | — |
| ThedaCare Cancer Care - Berlin | Berlin | Wisconsin | 54923 | — |
| Aurora Cancer Care-Southern Lakes VLCC | Burlington | Wisconsin | 53105 | — |
| Marshfield Clinic-Chippewa Center | Chippewa Falls | Wisconsin | 54729 | — |
| Marshfield Medical Center-EC Cancer Center | Eau Claire | Wisconsin | 54701 | — |
| Aurora Health Care Germantown Health Center | Germantown | Wisconsin | 53022 | — |
| Aurora Cancer Care-Grafton | Grafton | Wisconsin | 53024 | — |
| Aurora BayCare Medical Center | Green Bay | Wisconsin | 54311 | — |
| Aurora Cancer Care-Kenosha South | Kenosha | Wisconsin | 53142 | — |
| Marshfield Medical Center - Ladysmith | Ladysmith | Wisconsin | 54848 | — |
| Aurora Bay Area Medical Group-Marinette | Marinette | Wisconsin | 54143 | — |
| Marshfield Medical Center-Marshfield | Marshfield | Wisconsin | 54449 | — |
| Aurora Cancer Care-Milwaukee | Milwaukee | Wisconsin | 53209 | — |
| Aurora Saint Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
| Aurora Sinai Medical Center | Milwaukee | Wisconsin | 53233 | — |
| Marshfield Medical Center - Minocqua | Minocqua | Wisconsin | 54548 | — |
| ThedaCare Regional Medical Center - Neenah | Neenah | Wisconsin | 54956 | — |
| ThedaCare Cancer Care - New London | New London | Wisconsin | 54961 | — |
| Westfields Hospital/Cancer Center of Western Wisconsin | New Richmond | Wisconsin | 54017 | — |
| ThedaCare Cancer Care - Oshkosh | Oshkosh | Wisconsin | 54904 | — |
| Vince Lombardi Cancer Clinic - Oshkosh | Oshkosh | Wisconsin | 54904 | — |
| Aurora Cancer Care-Racine | Racine | Wisconsin | 53406 | — |
| Marshfield Medical Center-Rice Lake | Rice Lake | Wisconsin | 54868 | — |
| ThedaCare Cancer Care - Shawano | Shawano | Wisconsin | 54166 | — |
| Vince Lombardi Cancer Clinic-Sheboygan | Sheboygan | Wisconsin | 53081 | — |
| Marshfield Medical Center-River Region at Stevens Point | Stevens Point | Wisconsin | 54482 | — |
| Aurora Medical Center in Summit | Summit | Wisconsin | 53066 | — |
| Vince Lombardi Cancer Clinic-Two Rivers | Two Rivers | Wisconsin | 54241 | — |
| ThedaCare Cancer Care - Waupaca | Waupaca | Wisconsin | 54981 | — |
| Marshfield Clinic-Wausau Center | Wausau | Wisconsin | 54401 | — |
| Aurora Cancer Care-Milwaukee West | Wauwatosa | Wisconsin | 53226 | — |
| Aurora West Allis Medical Center | West Allis | Wisconsin | 53227 | — |
| Marshfield Medical Center - Weston | Weston | Wisconsin | 54476 | — |
| Marshfield Clinic - Wisconsin Rapids Center | Wisconsin Rapids | Wisconsin | 54494 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06216574, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 18, 2026 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06216574 live on ClinicalTrials.gov.