A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis (ICONIC-ADVANCE 2)
Public ClinicalTrials.gov record NCT06220604. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled and Deucravacitinib Active Comparator-controlled Study to Evaluate the Efficacy and Safety of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the study is to evaluate how effective JNJ-77242113 is in participants with moderate to severe plaque psoriasis compared to placebo and deucravacitinib.
Study identification
- NCT ID
- NCT06220604
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 731 participants
Conditions and interventions
Conditions
Interventions
- JNJ-77242113 Drug
- JNJ-77242113 Matching Placebo Drug
- Deucravacitinib Drug
- Deucravacitinib Matching Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 9, 2024 (Actual)
- Primary completion
- Nov 15, 2024 (Actual)
- Completion
- Sep 20, 2027 (Estimated)
- Last update posted
- Sep 28, 2026
2024 – 2027
United States locations
- U.S. sites
- 37
- U.S. states
- 18
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alliance Dermatology and MOHS Center P C | Phoenix | Arizona | 85032 | — |
| California Dermatology & Clinical Research Institute | Encinitas | California | 92024 | — |
| T Joseph Raoof Md Inc | Encino | California | 91436 | — |
| UCSF Fresno | Fresno | California | 93701 | — |
| University of California Los Angeles - Division of Dermatology | Los Angeles | California | 90024 | — |
| Wallace Medical Group, Inc | Los Angeles | California | 90056 | — |
| Dermatologist Medical Group of North County, Inc. | Oceanside | California | 92056 | — |
| Miami Dermatology And Laser Institute | Miami | Florida | 33133 | — |
| Bioclinical Research Alliance Inc. | Miami | Florida | 33155 | — |
| Forcare Clinical Research Inc | Tampa | Florida | 33613 | — |
| Southeast Dermatology Specialists | Douglasville | Georgia | 30135 | — |
| Arlington Dermatology | Rolling Meadows | Illinois | 60008 | — |
| Skin Sciences, PLLC | Louisville | Kentucky | 40217 | — |
| Qualmedica Research | Owensboro | Kentucky | 42301 | — |
| DermAssociates, PC | Rockville | Maryland | 20850 | — |
| Metro Boston Clinical Partners | Brighton | Massachusetts | 02135 | — |
| ActivMed Practices and Research | Methuen | Massachusetts | 01844 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Great Lakes Research Group | Bay City | Michigan | 48706 | — |
| The Derm Institute of West Michigan | Caledonia | Michigan | 49316 | — |
| Hamzavi Dermatology | Canton | Michigan | 48187 | — |
| Somerset Skin Centre | Troy | Michigan | 48084 | — |
| Cleaver Dermatology | Kirksville | Missouri | 63501 | — |
| Bexley dermatology research | Bexley | Ohio | 43209 | — |
| Essential Medical Research | Tulsa | Oklahoma | 74137 | — |
| Oregon Dermatology & Research Center | Portland | Oregon | 97210-2996 | — |
| Paddington Testing Co, Inc. | Philadelphia | Pennsylvania | 19103 | — |
| Clinical Research Center of the Carolinas LLC | Charleston | South Carolina | 29407 | — |
| Palmetto Clinical Trial Services, LLC | Greenville | South Carolina | 29615 | — |
| Arlington Research Center, Inc. | Arlington | Texas | 76011 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Dermatology Clinical Research Center of San Antonio | San Antonio | Texas | 78229 | — |
| Center for Clinical Studies | Webster | Texas | 77598 | — |
| Cope Family Medicine - Ogden Clinic | Bountiful | Utah | 84010 | — |
| Springville Dermatology CCT Research | Springville | Utah | 84663 | — |
| Kalo Clinical Research | West Valley City | Utah | 84120 | — |
| Virginia Dermatology Skin Cancer Center Pllc | Norfolk | Virginia | 23502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 91 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06220604, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 28, 2026 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06220604 live on ClinicalTrials.gov.