A Study of TL-925 Ophthalmic Emulsion as a Treatment for Dry Eye Disease
Public ClinicalTrials.gov record NCT06225973. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b, Multicenter, Randomized, Double-masked Vehicle-controlled Study to Evaluate the Efficacy and Safety of TL-925 Ophthalmic Emulsion 0.1% in Subjects With Moderate to Severe Dry Eye Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
In this prospective, phase 2b, multicenter, randomized, double-masked, vehicle-controlled, parallel-arm study, approximately 880 subjects with moderate to severe dry eye disease (DED) will be randomly assigned (1:1) to receive either TL-925 or vehicle as topical ophthalmic eye drops administered bilaterally BID. The study will comprise two phases: a two-week screening phase/run-in and a six-week double-masked treatment phase.
Study identification
- NCT ID
- NCT06225973
- Recruitment status
- Not listed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 880 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 6, 2024 (Actual)
- Primary completion
- Dec 2024 (Estimated)
- Completion
- Dec 2024 (Estimated)
- Last update posted
- Jul 10, 2024
2024
United States locations
- U.S. sites
- 18
- U.S. states
- 10
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cornea and Cataract Consultants of Arizona | Phoenix | Arizona | 85032 | — |
| Global Research Management | Glendale | California | 91204 | — |
| Nvision - La Mesa | La Mesa | California | 91942 | — |
| Nvision - Torrance | Torrance | California | 90505 | — |
| Wyse Eyecare | Northbrook | Illinois | 60062 | — |
| Pankratz Eye | Columbus | Indiana | 47203 | — |
| Butchertown Clinical | Louisville | Kentucky | 40206 | — |
| Andover Eye Associates - Andover | Andover | Massachusetts | 01810 | — |
| Andover Eye Associates - Raynham | Raynham | Massachusetts | 02767 | — |
| NEERA - Westborough | Westborough | Massachusetts | 01581 | — |
| NEERA - Woburn | Woburn | Massachusetts | 01801 | — |
| Oculus Research | Garner | North Carolina | 27529 | — |
| Wilmington Eye | Leland | North Carolina | 28451 | — |
| Scott and Christie EyeCare Associates | Cranberry Township | Pennsylvania | 16066 | — |
| Advancing Vision Research | Goodlettsville | Tennessee | 37072 | — |
| Total Eye Care, PA | Memphis | Tennessee | 38119 | — |
| Advancing Vision Research | Smyrna | Tennessee | 37167 | — |
| Piedmont Eye Center | Lynchburg | Virginia | 24502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06225973, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 10, 2024 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06225973 live on ClinicalTrials.gov.