A Safety and Efficacy Study of 2 Dosing Regimens of Recombinant Human Nerve Growth Factor (rhNGF) Eye Drop Solution Compared With Vehicle in Patients With Dry Eye Disease.
Public ClinicalTrials.gov record NCT06244316. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 4-Week, Phase II, Multicenter, Randomized, Double-Masked, Vehicle-Controlled, Parallel Group Study With 4 Weeks of Follow-Up to Evaluate Safety and Efficacy of a New Formulation of Recombinant Human Nerve Growth Factor (rhNGF) Eye Drop Solution at Two Different Concentrations in Patients With Dry Eye Disease
Study identification
- NCT ID
- NCT06244316
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Dompé Farmaceutici S.p.A
- Industry
- Enrollment
- 317 participants
Conditions and interventions
Conditions
Interventions
- rhNGF 5 μg/mL Drug
- rhNGF 10 μg/mL Drug
- Vehicle (Placebo solution) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 21, 2024
- Primary completion
- Dec 3, 2024
- Completion
- Dec 3, 2024
- Last update posted
- Feb 12, 2026
2024
United States locations
- U.S. sites
- 10
- U.S. states
- 9
- U.S. cities
- 10
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Eye Center | Chandler | Arizona | 85224 | — |
| East West Eye Institute | Torrance | California | 90505 | — |
| Vision Institute - Fontanero St | Colorado Springs | Colorado | 80907 | — |
| Sibia Eye Institute | Boynton Beach | Florida | 33437 | — |
| Eye Consultants of Atlanta | Atlanta | Georgia | 30339 | — |
| New England Eye Center - Boston | Boston | Massachusetts | 02111 | — |
| Eye Associates of North Jersey | Dover | New Jersey | 07801 | — |
| The Scheie Eye Institute | Philadelphia | Pennsylvania | 19104 | — |
| Total Eye Care PA | Memphis | Tennessee | 38119 | — |
| Toyos Clinic | Nashville | Tennessee | 37215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06244316, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 12, 2026 · Synced Jul 23, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06244316 live on ClinicalTrials.gov.