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Active, not recruiting Phase 1 Interventional

A Study of Valemetostat Tosylate in Combination With DXd ADCs in Subjects With Solid Tumors

ClinicalTrials.gov ID: NCT06244485

Public ClinicalTrials.gov record NCT06244485. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 2:17 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1b, Multicenter, Open-Label Study of Valemetostat Tosylate in Combination With DXd ADCs in Subjects With Solid Tumors

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will evaluate the safety, tolerability, and efficacy of valemetostat tosylate in combination with DXd ADC in patients with advanced solid tumors.

Study identification

NCT ID
NCT06244485
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
Daiichi Sankyo
Industry
Enrollment
98 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 15, 2024
Primary completion
Oct 31, 2028
Completion
Oct 31, 2028
Last update posted
Jul 20, 2026

2024 – 2028

United States locations

U.S. sites
17
U.S. states
13
U.S. cities
16
Facility City State ZIP Site status
City of Hope At Orange County Lennar Foundation Cancer Center Irvine California 92618
Sharp Memorial Hospital San Diego California 92123
Brcr Medical Center, Inc Dba Boca Raton Clinical Research Plantation Florida 33322
University of Hawaii At Manoa Honolulu Hawaii 96813
University of Chicago Medical Center Chicago Illinois 60637
Dana-Farber Cancer Institute Boston Massachusetts 02215
Memorial Sloan-Kettering Cancer Center (Mskcc) - New York New York New York 10065
Clinical Research Alliance Westbury New York 11590
Unc Hospitals Chapel Hill North Carolina 27514
The Cleveland Clinic Foundation Cleveland Ohio 44195
Providence Portland Medical Center Portland Oregon 97213
Mary Crowley Cancer Research Centers Dallas Texas 75230
Ut Southwestern Medical Center Dallas Texas 75390
University of Texas M. D. Anderson Cancer Center Houston Texas 77030
Next Virginia Fairfax Virginia 22031
Fred Hutchinson Cancer Center Seattle Washington 98109
Medical College of Wisconsin Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 18 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06244485, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 20, 2026 · Synced Sep 1, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06244485 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →