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Enrolling by invitation Not applicable Interventional

Extension to a Pivotal Study of Sensory Stimulation in Alzheimer's Disease (OLE Hope Study, CA-0015)

ClinicalTrials.gov ID: NCT06245031

Public ClinicalTrials.gov record NCT06245031. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 9, 2026, 4:24 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Open-Label Extension to a Randomized, Double-blind, Sham-controlled, Adaptive-Design Pivotal Study of Sensory Stimulation in Subjects With Alzheimer's Disease (OLE Hope Study, CA-0015)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is an open-label extension for a multicenter, randomized, double-blind, sham-controlled, adaptive design pivotal study. Participants who complete the Hope Study (CA-0011) will be eligible to consent for screening to enroll in the OLE Hope Study (CA-0015). All participants will be treated with an Active Sensory Stimulation System (GS120) for 60 minutes daily for up to 12 months. There will be no Sham treatment group or randomization involved in this study.

Study identification

NCT ID
NCT06245031
Recruitment status
Enrolling by invitation
Study type
Interventional
Phase
Not applicable
Lead sponsor
Cognito Therapeutics, Inc.
Industry
Enrollment
402 participants

Conditions and interventions

Eligibility (public fields only)

Age range
50 Years to 92 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 28, 2024
Primary completion
Nov 30, 2026
Completion
Feb 28, 2027
Last update posted
May 6, 2024

2024 – 2027

United States locations

U.S. sites
53
U.S. states
21
U.S. cities
51
Facility City State ZIP Site status
Barrow Neurological Institute Phoenix Arizona 85013
CCT Research - Foothills Research Center Phoenix Arizona 85044
Banner Sun Health Research Institute Sun City Arizona 85351
Advanced Research Center, Inc Anaheim California 92805
ATP Clinical Research, Inc. Costa Mesa California 92626
Neurology Center of North Orange County Fullerton California 92835
Syrentis Clinical Research Santa Ana California 92705
Office of Elizabeth Zarate-Rowell, MD Seal Beach California 90740
Mile High Research Center Denver Colorado 80218
JEM Research Institute Atlantis Florida 33462
South Lake Pain Institute Clermont Florida 34711
Arrow Clinical Trials Daytona Beach Florida 32117
Brain Matters Research Delray Beach Florida 33445
Neuropsychiatric Research Center of Southwest Florida Fort Myers Florida 33912
Charter Research - Lady Lake Lady Lake Florida 32792
Multi-Specialty Research Associates, Inc. Lake City Florida 23055
Coastal Family Medicine - Orange Park Orange Park Florida 32073
Emerald Coast Neurology Pensacola Florida 32504
Quantum Laboratories Pompano Beach Florida 33064
Progressive Medical Research Port Orange Florida 32127
Intercoastal Medical Group - Sarasota Sarasota Florida 34239
Suncoast Neuroscience Associates St. Petersburg Florida 33713
Brain Matters Research (Kane Center) Stuart Florida 34997
Conquest Research Winter Park Florida 32789
Charter Research - Winter Park Winter Park Florida 32792
Emory Alzheimer's Disease Research Center Atlanta Georgia 30329
NeuroStudies Decatur Georgia 30033
Great Lakes Clinical Trials- Flourish Research- Chicago Chicago Illinois 60640
Great Lakes Clinical Trials- Flourish Research- Gurnee Gurnee Illinois 60031
Northern Light Acadia Hospital Bangor Maine 04402
Boston Center for Memory Newton Massachusetts 02459
Office of Donald S. Marks, M.D., P.C. Plymouth Massachusetts 02360
Sisu BHR, LLC Springfield Massachusetts 01103
QUEST Research Institute Farmington Michigan 48334
Hattiesburg Clinic Hattiesburg Mississippi 39401
Las Vegas Medical Research Las Vegas Nevada 89113
The Cognitive and Research Center of New Jersey Springfield New Jersey 07081
Neurological Associates of Albany Albany New York 12208
Velocity Clinical Research - Syracuse East Syracuse New York 13057
Mid Hudson Medical Research New Windsor New York 12553
Alzheimer's Memory Center - AMC Research Matthews North Carolina 28105
Insight Clinical Trials, LLC Beachwood Ohio 44122
The Ohio State University Wexner Medical Center Columbus Ohio 43210
The Clinical Trial Center Jenkintown Pennsylvania 19046
Prisma Health Neurology Columbia South Carolina 29203
Coastal Neurology Port Royal South Carolina 29935
University of Tennessee Medical Center Knoxville Tennessee 37920
North Texas Clinical Trials Fort Worth Texas 76104
UT Health San Antonio, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases San Antonio Texas 78229
TRS Health Stafford Texas 77477
Mercury Clinical Research Sugar Land Texas 77478
Wasatch Clinical Research Salt Lake City Utah 84107
ReCogniton Health Fairfax Virginia 22031

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06245031, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 6, 2024 · Synced Sep 9, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06245031 live on ClinicalTrials.gov.

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