A Study to Evaluate Mavacamten in Adolescents With Symptomatic Obstructive Hypertrophic Cardiomyopathy
Public ClinicalTrials.gov record NCT06253221. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled Clinical Study to Evaluate Mavacamten in Adolescents (Age 12 Years to < 18 Years) With Symptomatic Obstructive Hypertrophic Cardiomyopathy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy, safety, and pharmacokinetics of mavacamten in adolescent patients with symptomatic obstructive hypertrophic cardiomyopathy (HCM).
Study identification
- NCT ID
- NCT06253221
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 44 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years to 17 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 17, 2024 (Actual)
- Primary completion
- Nov 25, 2025 (Actual)
- Completion
- Mar 28, 2031 (Estimated)
- Last update posted
- Dec 19, 2025
2024 – 2031
United States locations
- U.S. sites
- 31
- U.S. states
- 20
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution - 0017 | Birmingham | Alabama | 35294-0004 | — |
| Local Institution - 0050 | Phoenix | Arizona | 85016-7710 | — |
| Local Institution - 0032 | Los Angeles | California | 90027-6062 | — |
| Local Institution - 0008 | Los Angeles | California | 90095-8344 | — |
| Local Institution - 0033 | Palo Alto | California | 94304-1601 | — |
| Local Institution - 0044 | San Diego | California | 92123-4223 | — |
| Local Institution - 0038 | Aurora | Colorado | 80045-7106 | — |
| Local Institution - 0031 | St. Petersburg | Florida | 33701-4634 | — |
| Local Institution - 0053 | Atlanta | Georgia | 30329-3117 | — |
| Local Institution - 0013 | Chicago | Illinois | 60637-1447 | — |
| Local Institution - 0009 | Indianapolis | Indiana | 46202-5272 | — |
| Local Institution - 0043 | Boston | Massachusetts | 02115-5724 | — |
| Local Institution - 0002 | Ann Arbor | Michigan | 48109 | — |
| Local Institution - 0037 | St Louis | Missouri | 63110 | — |
| Local Institution - 0052 | Morristown | New Jersey | 07960 | — |
| Local Institution - 0010 | New Hyde Park | New York | 11042 | — |
| Local Institution - 0024 | New York | New York | 10029-6574 | — |
| Local Institution - 0036 | New York | New York | 10032-1559 | — |
| Local Institution - 0040 | The Bronx | New York | 10467-2403 | — |
| Local Institution - 0015 | Charlotte | North Carolina | 28204 | — |
| Local Institution - 0039 | Durham | North Carolina | 27705 | — |
| Local Institution - 0019 | Cincinnati | Ohio | 45229 | — |
| Local Institution - 0001 | Cleveland | Ohio | 44195-0001 | — |
| Local Institution - 0029 | Columbus | Ohio | 43205 | — |
| Local Institution - 0030 | Philadelphia | Pennsylvania | 19104-4319 | — |
| Local Institution - 0005 | Pittsburgh | Pennsylvania | 15224-1334 | — |
| Local Institution - 0034 | Memphis | Tennessee | 38105 | — |
| Local Institution - 0045 | Austin | Texas | 78712 | — |
| Local Institution - 0054 | Houston | Texas | 77030 | — |
| Local Institution - 0003 | Salt Lake City | Utah | 84113-1103 | — |
| Local Institution - 0012 | Charlottesville | Virginia | 22908-0816 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06253221, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 19, 2025 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06253221 live on ClinicalTrials.gov.