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Active, not recruiting Phase 3 Interventional

A Study to Evaluate Mavacamten in Adolescents With Symptomatic Obstructive Hypertrophic Cardiomyopathy

ClinicalTrials.gov ID: NCT06253221

Public ClinicalTrials.gov record NCT06253221. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 12:04 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Placebo-controlled Clinical Study to Evaluate Mavacamten in Adolescents (Age 12 Years to < 18 Years) With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Study identification

NCT ID
NCT06253221
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Bristol-Myers Squibb
Industry
Enrollment
44 participants

Conditions and interventions

Interventions

  • Mavacamten Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
12 Years to 17 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 16, 2024
Primary completion
Nov 24, 2025
Completion
Mar 27, 2031
Last update posted
Dec 18, 2025

2024 – 2031

United States locations

U.S. sites
31
U.S. states
20
U.S. cities
29
Facility City State ZIP Site status
Local Institution - 0017 Birmingham Alabama 35294-0004
Local Institution - 0050 Phoenix Arizona 85016-7710
Local Institution - 0032 Los Angeles California 90027-6062
Local Institution - 0008 Los Angeles California 90095-8344
Local Institution - 0033 Palo Alto California 94304-1601
Local Institution - 0044 San Diego California 92123-4223
Local Institution - 0038 Aurora Colorado 80045-7106
Local Institution - 0031 St. Petersburg Florida 33701-4634
Local Institution - 0053 Atlanta Georgia 30329-3117
Local Institution - 0013 Chicago Illinois 60637-1447
Local Institution - 0009 Indianapolis Indiana 46202-5272
Local Institution - 0043 Boston Massachusetts 02115-5724
Local Institution - 0002 Ann Arbor Michigan 48109
Local Institution - 0037 St Louis Missouri 63110
Local Institution - 0052 Morristown New Jersey 07960
Local Institution - 0010 New Hyde Park New York 11042
Local Institution - 0024 New York New York 10029-6574
Local Institution - 0036 New York New York 10032-1559
Local Institution - 0040 The Bronx New York 10467-2403
Local Institution - 0015 Charlotte North Carolina 28204
Local Institution - 0039 Durham North Carolina 27705
Local Institution - 0019 Cincinnati Ohio 45229
Local Institution - 0001 Cleveland Ohio 44195-0001
Local Institution - 0029 Columbus Ohio 43205
Local Institution - 0030 Philadelphia Pennsylvania 19104-4319
Local Institution - 0005 Pittsburgh Pennsylvania 15224-1334
Local Institution - 0034 Memphis Tennessee 38105
Local Institution - 0045 Austin Texas 78712
Local Institution - 0054 Houston Texas 77030
Local Institution - 0003 Salt Lake City Utah 84113-1103
Local Institution - 0012 Charlottesville Virginia 22908-0816

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06253221, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 18, 2025 · Synced Jul 21, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06253221 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →