A Study of the Efficacy and Safety of SP-624 in the Treatment of Adults With Major Depressive Disorder
Public ClinicalTrials.gov record NCT06254612. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-center, Double-Blind, Randomized, Placebo-Controlled Study of the Efficacy and Safety of SP-624 in the Treatment of Adults With Major Depressive Disorder
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 2B clinical study evaluating the effectiveness and safety of SP-624 as compared to placebo in the treatment of adults with Major Depressive Disorder.
Study identification
- NCT ID
- NCT06254612
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 497 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 25, 2024 (Actual)
- Primary completion
- Jul 8, 2026 (Actual)
- Completion
- Jul 8, 2026 (Actual)
- Last update posted
- Aug 18, 2026
2024 – 2026
United States locations
- U.S. sites
- 50
- U.S. states
- 24
- U.S. cities
- 49
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| IMA Clinical Research | Phoenix | Arizona | 85012 | — |
| Noble Clinical Research | Tucson | Arizona | 85704 | — |
| SanRo Clinical Research Group | Bryant | Arkansas | 72022 | — |
| Clinical Innovations | Bellflower | California | 90706 | — |
| Sun Valley Research Center | Imperial | California | 92251 | — |
| Synergy San Diego | Lemon Grove | California | 91945 | — |
| Excell Research | Oceanside | California | 92056 | — |
| CiTrials | Riverside | California | 92506 | — |
| Collaborative Neuroscience Research | Torrance | California | 90504 | — |
| Sunwise Clinical Research | Walnut Creek | California | 94596 | — |
| Next Level Clinical Trials | West Covina | California | 91790 | — |
| MCB Clinical Research Centers | Colorado Springs | Colorado | 80910 | — |
| Clinical Neuroscience Solutions | Jacksonville | Florida | 32256 | — |
| Accel Clinical | Lakeland | Florida | 33803 | — |
| Segal Trials | Lauderhill | Florida | 33319 | — |
| Segal Trials - Miami Lakes | Miami Lakes | Florida | 33016 | — |
| Clinical Neuroscience Solutions | Orlando | Florida | 32801 | — |
| DMI Research | Pinellas Park | Florida | 33782 | — |
| Accelerated Enrollment Solutions | Atlanta | Georgia | 30328 | — |
| Velocity Clinical Research | Meridian | Idaho | 83642 | — |
| Revive Research Institute | Elgin | Illinois | 60123 | — |
| Tandem Clinical Research | Marrero | Louisiana | 70072 | — |
| Boston Clinical Trials | Boston | Massachusetts | 02131 | — |
| Neurobehavioral Medicine Group | Bloomfield Hills | Michigan | 48302 | — |
| Midwest Research Group | Saint Charles | Missouri | 63304 | — |
| Alivation Research | Lincoln | Nebraska | 68526 | — |
| IMA Clinical Research | Las Vegas | Nevada | 89102 | — |
| Redbird Research | Las Vegas | Nevada | 89119 | — |
| Center for Emotional Fitness | Cherry Hill | New Jersey | 08002 | — |
| CenExel HRI | Marlton | New Jersey | 08053 | — |
| IMA Clinical Research | Albuquerque | New Mexico | 87109 | — |
| Integrative Clinical Trials | Brooklyn | New York | 11229 | — |
| Pioneer Clinical Research | New York | New York | 10016 | — |
| Magnolia Clinical Research | Cary | North Carolina | 27511 | — |
| UNC Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| New Hope Clinical Research | Charlotte | North Carolina | 28211 | — |
| Velocity Clinical Research | Beachwood | Ohio | 44122 | — |
| Midwest Clinical Research Center | Dayton | Ohio | 45417 | — |
| North Star Medical Research | Middleburg Heights | Ohio | 44130 | — |
| Summit Headlands | Portland | Oregon | 97210 | — |
| Coastal Carolina Research Center | North Charleston | South Carolina | 29405 | — |
| Clinical Neuroscience Solutions | Memphis | Tennessee | 38119 | — |
| Donald J. Garcia, Jr, MD, PA | Austin | Texas | 78737 | — |
| Future Search Trials of Dallas | Dallas | Texas | 75231 | — |
| Haracec Clinical Research | El Paso | Texas | 79902 | — |
| Pillar Clinical Research | Richardson | Texas | 75080 | — |
| R and H Clinical Research | Stafford | Texas | 77477 | — |
| Grayline Research Center | Wichita Falls | Texas | 76309 | — |
| Northwest Clinical Research Center | Bellevue | Washington | 98007 | — |
| Core Clinical Research | Everett | Washington | 98201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06254612, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 18, 2026 · Synced Oct 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06254612 live on ClinicalTrials.gov.