Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

ClinicalTrials.gov ID: NCT06297226

Public ClinicalTrials.gov record NCT06297226. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Jul 23, 2026, 7:00 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Open-Label, Multicenter Study of Arlocabtagene Autoleucel (BMS-986393), a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma (QUINTESSENTIAL)

Study identification

NCT ID: NCT06297226
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company; Industry
Enrollment: 230 participants

Conditions and interventions

Conditions

Multiple Myeloma

Interventions

Arlocabtagene Autoleucel Biological

Biological

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Mar 20, 2024
Primary completion: Jun 29, 2027
Completion: Jun 29, 2032
Last update posted: May 27, 2026

2024 – 2032

United States locations

U.S. sites: 41
U.S. states: 27
U.S. cities: 36

Facility	City	State	ZIP	Site status
University of Alabama at Birmingham	Birmingham	Alabama	35294-3300	Recruiting
Banner MD Anderson Cancer Center	Gilbert	Arizona	85234	Recruiting
University of Arkansas for Medical Sciences	Little Rock	Arkansas	72205	Recruiting
UCLA Hematology/Oncology - Westwood (Building 200 Suite 214)	Los Angeles	California	90095	Recruiting
UCSF Helen Diller Medical Center at Parnassus Heights	San Francisco	California	94143	Recruiting
Colorado Blood Cancer Institute	Denver	Colorado	80218	Recruiting
Mayo Clinic in Florida	Jacksonville	Florida	32224	Recruiting
Miami Cancer Institute at Baptist Health, Inc.	Miami	Florida	33176	Recruiting
Moffitt Cancer Center	Tampa	Florida	33612	Recruiting
Winship Cancer Institute of Emory University	Atlanta	Georgia	30322	Recruiting
Northside Hospital	Atlanta	Georgia	30342	Recruiting
Northwestern Memorial Hospital	Chicago	Illinois	60611	Recruiting
University of Chicago Medical Center	Chicago	Illinois	60637	Recruiting
University of Iowa	Iowa City	Iowa	52242	Recruiting
The University of Kansas Cancer Center - Westwood	Westwood	Kansas	66205	Recruiting
Norton Women's and Children's Hospital	Louisville	Kentucky	40207	Recruiting
Local Institution - 0065	Baltimore	Maryland	21218	Withdrawn
Massachusetts General Hospital	Boston	Massachusetts	02114	Recruiting
Dana-Farber Cancer Institute	Boston	Massachusetts	02215	Recruiting
Mayo Clinic in Rochester, Minnesota	Rochester	Minnesota	55905	Recruiting
Washington University School of Medicine	St Louis	Missouri	63110	Recruiting
Rutgers Cancer Institute of New Jersey	New Brunswick	New Jersey	08901	Recruiting
Roswell Park Cancer Institute	Buffalo	New York	14263	Recruiting
Icahn School of Medicine at Mount Sinai	New York	New York	10029	Recruiting
Memorial Sloan Kettering Cancer Center	New York	New York	10065	Recruiting
University of North Carolina Medical Center	Chapel Hill	North Carolina	27599-7305	Recruiting
Local Institution - 0067	Charlotte	North Carolina	28204	Withdrawn
Oncology Hematology Care	Cincinnati	Ohio	45242	Recruiting
The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer Center	Columbus	Ohio	43210	Recruiting
Oregon Health and Science University	Portland	Oregon	97239	Recruiting
Sidney Kimmel Cancer Center - Jefferson Health	Philadelphia	Pennsylvania	19107	Recruiting
Tennessee Oncology	Nashville	Tennessee	37203	Recruiting
Vanderbilt University Medical Center	Nashville	Tennessee	37232	Recruiting
Local Institution - 0069	Austin	Texas	78704	Withdrawn
UT Southwestern Medical Center	Dallas	Texas	75390	Recruiting
University of Texas MD Anderson Cancer Center	Houston	Texas	77030	Recruiting
Methodist HealthCare System of San Antonio Clinical Trials Office, Texas Transplant Institute	San Antonio	Texas	78229	Recruiting
LDS Hospital	Salt Lake City	Utah	84143	Recruiting
Virginia Oncology Associates	Norfolk	Virginia	23502	Recruiting
Fred Hutchinson Cancer Center	Seattle	Washington	98109	Recruiting
University of Wisconsin Carbone Cancer Center - University Hospital	Madison	Wisconsin	53792	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06297226, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted May 27, 2026 · Synced Jul 23, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06297226 live on ClinicalTrials.gov.

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