Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

ClinicalTrials.gov ID: NCT06307652

Public ClinicalTrials.gov record NCT06307652. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 5, 2026, 7:42 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Randomised, Double-blind Study to Evaluate the Effect of Balcinrenone/Dapagliflozin, Compared With Dapagliflozin, on the Risk of Heart Failure Events and Cardiovascular Death in Patients With Heart Failure and Impaired Kidney Function

Study identification

NCT ID: NCT06307652
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: AstraZeneca; Industry
Enrollment: 4,800 participants

Conditions and interventions

Conditions

Heart Failure and Impaired Kidney Function

Interventions

balcinrenone/dapagliflozin 15 mg/10 mg and matching placebo for dapagliflozin 10 mg Drug
balcinrenone/dapagliflozin 40 mg/10 mg and matching placebo for dapagliflozin 10 mg Drug
dapagliflozin 10 mg and matching placebo for balcinrenone/dapagliflozin Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 130 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Apr 11, 2024
Primary completion: Jun 10, 2027
Completion: Jun 10, 2027
Last update posted: Apr 26, 2026

2024 – 2027

United States locations

U.S. sites: 166
U.S. states: 37
U.S. cities: 145

Facility	City	State	ZIP	Site status
Research Site	Alexander City	Alabama	35010	Recruiting
Research Site	Birmingham	Alabama	35209	Withdrawn
Research Site	Fairhope	Alabama	36532	Recruiting
Research Site	Huntsville	Alabama	35801	Recruiting
Research Site	Phoenix	Arizona	85016	Recruiting
Research Site	Phoenix	Arizona	85044	Recruiting
Research Site	Little Rock	Arkansas	72205	Recruiting
Research Site	Beverly Hills	California	90211	Recruiting
Research Site	Covina	California	91723	Recruiting
Research Site	Encinitas	California	92024	Recruiting
Research Site	Los Angeles	California	90073	Recruiting
Research Site	Los Angeles	California	90089	Recruiting
Research Site	Newport Beach	California	92663	Terminated
Research Site	Orange	California	92868	Withdrawn
Research Site	Redding	California	96001	Recruiting
Research Site	San Diego	California	92123	Recruiting
Research Site	San Francisco	California	94110	Recruiting
Research Site	San Francisco	California	94121	Recruiting
Research Site	Santa Ana	California	92704	Withdrawn
Research Site	Thousand Oaks	California	91360	Terminated
Research Site	Vista	California	92081	Recruiting
Research Site	West Hills	California	91307	Recruiting
Research Site	Aurora	Colorado	80045	Recruiting
Research Site	Wheat Ridge	Colorado	80033	Terminated
Research Site	Altamonte Springs	Florida	32701	Terminated
Research Site	Boca Raton	Florida	33486	Recruiting
Research Site	Bradenton	Florida	34209	Recruiting
Research Site	Clearwater	Florida	33756	Withdrawn
Research Site	Delray Beach	Florida	33484	Recruiting
Research Site	Fort Lauderdale	Florida	33308	Recruiting
Research Site	Gainesville	Florida	32610	Recruiting
Research Site	Jacksonville	Florida	32209	Recruiting
Research Site	Miami	Florida	33133	Terminated
Research Site	Miami	Florida	33176	Recruiting
Research Site	Miami Lakes	Florida	33014	Recruiting
Research Site	Palm Beach Gardens	Florida	33410	Recruiting
Research Site	Pensacola	Florida	32503	Recruiting
Research Site	Port Charlotte	Florida	33952	Withdrawn
Research Site	Safety Harbor	Florida	34695	Recruiting
Research Site	Saint Augustine	Florida	32086	Recruiting
Research Site	St. Petersburg	Florida	33701	Recruiting
Research Site	Tampa	Florida	33617	Recruiting
Research Site	Atlanta	Georgia	30303	Recruiting
Research Site	Atlanta	Georgia	30309	Recruiting
Research Site	Peachtree City	Georgia	30269	Recruiting
Research Site	Thomasville	Georgia	31792	Recruiting
Research Site	Tucker	Georgia	30084	Recruiting
Research Site	Chicago	Illinois	60612	Withdrawn
Research Site	Chicago	Illinois	60637	Recruiting
Research Site	Glenview	Illinois	60026	Recruiting
Research Site	Hazel Crest	Illinois	60429	Recruiting
Research Site	North Chicago	Illinois	60064	Terminated
Research Site	Peoria	Illinois	61614	Recruiting
Research Site	Winfield	Illinois	60190	Recruiting
Research Site	Elkhart	Indiana	46514	Recruiting
Research Site	Evansville	Indiana	47710	Recruiting
Research Site	Hammond	Indiana	46324	Recruiting
Research Site	Indianapolis	Indiana	46237	Withdrawn
Research Site	Muncie	Indiana	47303	Recruiting
Research Site	Munster	Indiana	46321	Recruiting
Research Site	Richmond	Indiana	47374	Withdrawn
Research Site	Waterloo	Iowa	50701	Recruiting
Research Site	Wichita	Kansas	67218	Withdrawn
Research Site	Wichita	Kansas	67226	Recruiting
Research Site	Louisville	Kentucky	40202	Terminated
Research Site	Alexandria	Louisiana	71301	Withdrawn
Research Site	New Orleans	Louisiana	70121	Withdrawn
Research Site	Shreveport	Louisiana	71105	Withdrawn
Research Site	West Monroe	Louisiana	71291	Recruiting
Research Site	Augusta	Maine	04330	Withdrawn
Research Site	Rockville	Maryland	20850	Recruiting
Research Site	Boston	Massachusetts	02114	Recruiting
Research Site	Fall River	Massachusetts	02721	Withdrawn
Research Site	Worcester	Massachusetts	01655	Recruiting
Research Site	Ann Arbor	Michigan	48109	Withdrawn
Research Site	Bloomfield Hills	Michigan	48304	Recruiting
Research Site	Dearborn	Michigan	48126	Terminated
Research Site	Farmington Hills	Michigan	48334	Recruiting
Research Site	Flint	Michigan	48504	Recruiting
Research Site	Troy	Michigan	48098	Withdrawn
Research Site	Ypsilanti	Michigan	48197	Recruiting
Research Site	Minneapolis	Minnesota	55455	Withdrawn
Research Site	Saint Paul	Minnesota	55109	Recruiting
Research Site	Jackson	Mississippi	39216	Recruiting
Research Site	Columbia	Missouri	65201	Recruiting
Research Site	Kansas City	Missouri	64111	Recruiting
Research Site	Kansas City	Missouri	64128	Recruiting
Research Site	Lincoln	Nebraska	68506	Recruiting
Research Site	Lincoln	Nebraska	68510	Recruiting
Research Site	Henderson	Nevada	89074	Recruiting
Research Site	North Las Vegas	Nevada	89086	Withdrawn
Research Site	Bridgewater	New Jersey	08807	Withdrawn
Research Site	Jersey City	New Jersey	07302	Recruiting
Research Site	Somerset	New Jersey	08873	Recruiting
Research Site	Albany	New York	12208	Withdrawn
Research Site	Brooklyn	New York	11219	Not yet recruiting
Research Site	Brooklyn	New York	11220	Recruiting
Research Site	Clifton Park	New York	12065	Not yet recruiting
Research Site	Manhasset	New York	11030	Withdrawn
Research Site	New Windsor	New York	12553	Withdrawn
Research Site	New York	New York	10029	Recruiting
Research Site	Staten Island	New York	10310	Recruiting
Research Site	Stony Brook	New York	11794	Withdrawn
Research Site	The Bronx	New York	10451	Recruiting
Research Site	The Bronx	New York	10455	Recruiting
Research Site	Asheville	North Carolina	28801	Recruiting
Research Site	Chapel Hill	North Carolina	27517	Recruiting
Research Site	Charlotte	North Carolina	28204	Recruiting
Research Site	Durham	North Carolina	27710	Recruiting
Research Site	Greensboro	North Carolina	27405	Withdrawn
Research Site	Pinehurst	North Carolina	28374	Recruiting
Research Site	Statesville	North Carolina	28625	Recruiting
Research Site	Wilmington	North Carolina	28401	Recruiting
Research Site	Cincinnati	Ohio	45219	Recruiting
Research Site	Cincinnati	Ohio	45267	Recruiting
Research Site	Dayton	Ohio	45414	Recruiting
Research Site	Maumee	Ohio	43537	Withdrawn
Research Site	Springfield	Ohio	45504	Recruiting
Research Site	Oklahoma City	Oklahoma	73102	Withdrawn
Research Site	Portland	Oregon	97225	Recruiting
Research Site	Abington	Pennsylvania	19001	Recruiting
Research Site	Camp Hill	Pennsylvania	17011	Recruiting
Research Site	Hershey	Pennsylvania	17033	Recruiting
Research Site	Horsham	Pennsylvania	19044	Terminated
Research Site	Philadelphia	Pennsylvania	19104	Recruiting
Research Site	Providence	Rhode Island	02908	Recruiting
Research Site	Anderson	South Carolina	29621	Terminated
Research Site	Charleston	South Carolina	29401	Recruiting
Research Site	Charleston	South Carolina	29425	Recruiting
Research Site	Ladson	South Carolina	29456	Withdrawn
Research Site	Lancaster	South Carolina	29720	Recruiting
Research Site	Rapid City	South Dakota	57701	Recruiting
Research Site	Jackson	Tennessee	38305	Recruiting
Research Site	Knoxville	Tennessee	37916	Recruiting
Research Site	Memphis	Tennessee	38120	Recruiting
Research Site	Memphis	Tennessee	38128	Terminated
Research Site	Nashville	Tennessee	37212	Recruiting
Research Site	Tullahoma	Tennessee	37388	Recruiting
Research Site	Allen	Texas	75013	Recruiting
Research Site	Amarillo	Texas	79106	Recruiting
Research Site	Amarillo	Texas	79121	Recruiting
Research Site	Cypress	Texas	77429	Recruiting
Research Site	Dallas	Texas	75204	Recruiting
Research Site	Dallas	Texas	75216	Recruiting
Research Site	Dallas	Texas	75390	Recruiting
Research Site	El Paso	Texas	79905	Recruiting
Research Site	Houston	Texas	77002	Terminated
Research Site	Houston	Texas	77025	Recruiting
Research Site	Katy	Texas	77493	Terminated
Research Site	Mansfield	Texas	76063	Terminated
Research Site	McKinney	Texas	75069	Recruiting
Research Site	McKinney	Texas	75071	Recruiting
Research Site	Odessa	Texas	79761	Recruiting
Research Site	Pearland	Texas	77584	Suspended
Research Site	San Antonio	Texas	78229	Recruiting
Research Site	Sherman	Texas	75092	Terminated
Research Site	Temple	Texas	76508	Recruiting
Research Site	Tyler	Texas	75701	Recruiting
Research Site	Tyler	Texas	75702	Recruiting
Research Site	Salt Lake City	Utah	84107	Withdrawn
Research Site	Salt Lake City	Utah	84148	Recruiting
Research Site	Falls Church	Virginia	22042	Recruiting
Research Site	Newport News	Virginia	23606	Recruiting
Research Site	Puyallup	Washington	98372	Withdrawn
Research Site	Seattle	Washington	98101	Withdrawn
Research Site	Tacoma	Washington	98405	Withdrawn

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 668 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06307652, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 26, 2026 · Synced May 5, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06307652 live on ClinicalTrials.gov.

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