ClinicalTrials.gov record
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)
ClinicalTrials.gov ID: NCT06383390
Public ClinicalTrials.gov record NCT06383390. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 4, 2026, 4:40 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Event-Driven Study to Investigate the Effect of Retatrutide on the Incidence of Major Adverse Cardiovascular Events and Major Adverse Kidney Events in Participants With Body Mass Index ≥27 kg/m2 and Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease
Study identification
- NCT ID
- NCT06383390
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Eli Lilly and Company
- Industry
- Enrollment
- 10,000 participants
Conditions and interventions
Interventions
- Placebo Drug
- Retatrutide Drug
Drug
Eligibility (public fields only)
- Age range
- 45 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 29, 2024
- Primary completion
- Jan 31, 2029
- Completion
- Jan 31, 2029
- Last update posted
- Apr 19, 2026
2024 – 2029
United States locations
- U.S. sites
- 206
- U.S. states
- 34
- U.S. cities
- 161
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alabama Kidney Research | Alabaster | Alabama | 35007 | — |
| Central Research Associates | Birmingham | Alabama | 35205 | — |
| Alliance for Multispecialty Research, LLC | Daphne | Alabama | 36526 | — |
| Nephrology Consultants | Huntsville | Alabama | 35805 | — |
| Alliance for Multispecialty Research, LLC | Mobile | Alabama | 36608 | — |
| Prime Medical Group, LLC dba Gilbert Center for Family Medicine, LLC | Gilbert | Arizona | 85296 | — |
| Sun City Clinical Research | Glendale | Arizona | 85304 | — |
| Arizona Kidney Disease & Hypertension Center (AKDHC) - Thunderbird | Glendale | Arizona | 85306 | — |
| Helios Clinical Research - SAZ-PDV-026 | Paradise Valley | Arizona | 85253 | — |
| Banner University Medical Center Phoenix | Phoenix | Arizona | 85006 | — |
| Phoenix Clinical LLC | Phoenix | Arizona | 85014 | — |
| Elite Clinical Studies, LLC | Phoenix | Arizona | 85018 | — |
| Absolute Clinical Research | Phoenix | Arizona | 85051 | — |
| Scottsdale Clinical Trials | Scottsdale | Arizona | 85260 | — |
| Clinical Research Institute of Arizona (CRI) - Sun City West | Sun City West | Arizona | 85375 | — |
| Synexus Clinical Research US, Inc./Orange Grove Family Practice | Tucson | Arizona | 85741 | — |
| Cardiology and Medicine Clinic | Little Rock | Arkansas | 72204 | — |
| Kidney & Hypertension Center - Apple Valley | Apple Valley | California | 92307 | — |
| Invivo - Bakersfield | Bakersfield | California | 93309 | — |
| American Institute of Research | Beverly Hills | California | 90211 | — |
| Hope Clinical Research, Inc. | Canoga Park | California | 91303 | — |
| Valley Clinical Trials, Inc. | Covina | California | 91723 | — |
| North Coast Cardiology | Encinitas | California | 92024 | — |
| Neighborhood Healthcare Institute of Health | Escondido | California | 92025 | — |
| HB Clinical Trials - Fountain Valley | Fountain Valley | California | 92708 | — |
| Care Access - Huntington Beach | Huntington Beach | California | 92648 | — |
| Irvine Clinical Research | Irvine | California | 92614 | — |
| Scripps Whittier Diabetes Institute | La Jolla | California | 92037 | — |
| Long Beach Research Institute | Long Beach | California | 90805 | — |
| Ark Clinical Research | Long Beach | California | 90815 | — |
| North America Research Institute | Lynwood | California | 90262 | — |
| Valley Clinical Trials, Inc. | Northridge | California | 91325 | — |
| Desert Oasis Healthcare Medical Group | Palm Springs | California | 92262 | — |
| California Liver Research Institute | Pasadena | California | 91105 | — |
| Western University of Health Sciences | Pomona | California | 91766 | — |
| California Kidney Specialists | San Dimas | California | 91773 | — |
| Southern California Clinical Research | Santa Ana | California | 92701 | — |
| Care Access - Santa Clarita | Santa Clarita | California | 91321 | — |
| Encompass Clinical Research | Spring Valley | California | 91978 | — |
| Valiance Clinical Research | Tarzana | California | 91356 | — |
| Care Access - Thousand Oaks | Thousand Oaks | California | 91360 | — |
| Med Partners, Inc. dba Premiere Medical Center of Burbank, Inc. | Toluca Lake | California | 91602 | — |
| Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | Torrance | California | 90502 | — |
| UCLA South Bay Endocrinology | Torrance | California | 90505 | — |
| InvivoCure | Van Nuys | California | 91405 | — |
| National Institute of Clinical Research (NICR) - High Desert | Victorville | California | 92392 | — |
| Synexus Clinical Research US, Inc. | Vista | California | 92083 | — |
| Millennium Clinical Trials | Westlake Village | California | 91361 | — |
| Western Nephrology | Arvada | Colorado | 80002 | — |
| University of Colorado Anschutz Medical Campus | Aurora | Colorado | 80045 | — |
| Cardiology Associates of Fairfield County, P.C. | Stamford | Connecticut | 06905 | — |
| Chase Medical Research, LLC | Waterbury | Connecticut | 06708 | — |
| Excel Medical Clinical Trials | Boca Raton | Florida | 33434 | — |
| American Research Institute | Cutler Bay | Florida | 33157 | — |
| Fleming Island Center for Clinical Research | Fleming Island | Florida | 32003 | — |
| Jellinger and Lerman, MD PA dba The Center for Diabetes and Endocrine Care | Fort Lauderdale | Florida | 33312 | — |
| Florida Kidney Physicians - Fort Lauderdale | Fort Lauderdale | Florida | 33316 | — |
| East Coast Institute for Research, LLC | Jacksonville | Florida | 32216 | — |
| Lakeview Institute of Clinical Research | Leesburg | Florida | 34748 | — |
| Flourish Research - Miami, LLC | Miami | Florida | 33135 | — |
| New Age Medical Research Corporation | Miami | Florida | 33186 | — |
| Onhealth Research Center | Miami | Florida | 33186 | — |
| Inpatient Research Clinic | Miami Lakes | Florida | 33014 | — |
| CTR Oakwater, LLC | Orlando | Florida | 32806 | — |
| Omega Research Orlando | Orlando | Florida | 32808 | — |
| Florida Kidney Physicians, LLC | Port Charlotte | Florida | 33952 | — |
| Florida Kidney Physicians - Tampa | Riverview | Florida | 33578 | — |
| Cardiovascular Center of Sarasota | Sarasota | Florida | 34239 | — |
| Care Access - Tamarac | Tamarac | Florida | 33321 | — |
| MOORE Clinical Research, Inc. d/b/a TrueBlue Clinical Research | Tampa | Florida | 33607 | — |
| Care Access - Tampa | Tampa | Florida | 33625 | — |
| American Clinical Trials - Acworth | Acworth | Georgia | 30101 | — |
| Atlanta Diabetes Associates | Atlanta | Georgia | 30318 | — |
| Emory University School of Medicine | Atlanta | Georgia | 30322 | — |
| Fides Clinical Research | Atlanta | Georgia | 30342 | — |
| Southeastern Clinical Research Institute | Augusta | Georgia | 30904 | — |
| American Clinical Trials - Douglasville | Douglasville | Georgia | 30134 | — |
| Center for Advanced Research & Education | Gainesville | Georgia | 30501 | — |
| The Jones Center Clinical Research | Macon | Georgia | 31210 | — |
| North Georgia Clinical Research | Woodstock | Georgia | 30189 | — |
| Great Lakes Clinical Trials - Ravenswood | Chicago | Illinois | 60640 | — |
| Clinical Investigation Specialists | Gurnee | Illinois | 60031 | — |
| Nephrology Associates of Northern Illinois and Indiana (NANI) - Hinsdale | Hinsdale | Illinois | 60521 | — |
| Accellacare - DuPage | Lombard | Illinois | 60148 | — |
| Alliance for Multispecialty Research, LLC | Niles | Illinois | 60714 | — |
| Rockford Nephrology Associates | Rockford | Illinois | 61107 | — |
| Central Illinois Diabetes and Clinical Research a Division of Prairie Education and Research Cooperative | Springfield | Illinois | 62711 | — |
| Qualmedica Research, LLC | Evansville | Indiana | 47715 | — |
| Nephrology Associates of Northern Illinois and Indiana (NANI) - Fort Wayne | Fort Wayne | Indiana | 46804 | — |
| Indiana University Health Methodist Hospital | Indianapolis | Indiana | 46202 | — |
| Nephrology Associates of Northern Illinois and Indiana - IKS - Indianapolis South | Indianapolis | Indiana | 46227 | — |
| Care Access - South Indianapolis | Indianapolis | Indiana | 46254 | — |
| Reid Physician Associates | Richmond | Indiana | 47374 | — |
| Iowa Diabetes and Endocrinology Research Center | West Des Moines | Iowa | 50266 | — |
| The University of Kansas - Clinical Research Center | Fairway | Kansas | 66205 | — |
| Alliance for Multispecialty Research, LLC | Newton | Kansas | 67114 | — |
| Cotton O'Neil Clinical Research Center | Topeka | Kansas | 66606 | — |
| Cotton O'Neil Diabetes & Endocrinology | Topeka | Kansas | 66606 | — |
| Qualmedica Research | Bowling Green | Kentucky | 42101 | — |
| Alliance for Multispecialty Research, LLC | Lexington | Kentucky | 40509 | — |
| L-MARC Research Center | Louisville | Kentucky | 40213 | — |
| Care Access - Lake Charles | Lake Charles | Louisiana | 70601 | — |
| IMA Clinical Research Monroe - Armand | Monroe | Louisiana | 71201 | — |
| Alliance for Multispecialty Research, LLC | New Orleans | Louisiana | 70119 | — |
| Sinai Hospital Of Baltimore | Baltimore | Maryland | 21209 | — |
| Care Access - Baltimore | Baltimore | Maryland | 21213 | — |
| Ascension Saint Agnes Heart Care | Baltimore | Maryland | 21229 | — |
| MedStar Good Samaritan Hospital | Baltimore | Maryland | 21239 | — |
| Jadestone Clinical Research | Beltsville | Maryland | 20705 | — |
| Anderson Medical Research | Ft. Washington | Maryland | 20744 | — |
| MedStar Health Research Institute (MedStar Physician Based Research Network) | Hyattsville | Maryland | 20782 | — |
| NECCR PrimaCare Research | Fall River | Massachusetts | 02721 | — |
| Care Access - Quincy | Quincy | Massachusetts | 02169 | — |
| Revival Research Institute, LLC | Dearborn | Michigan | 48126 | — |
| Elixia MKC, LLC | Pontiac | Michigan | 48341 | — |
| Lake Michigan Nephrology | Saint Joseph | Michigan | 49085 | — |
| Great Lakes Research Institute | Southfield | Michigan | 48075 | — |
| Arcturus Healthcare , PLC, Troy Internal Medicine Research Division | Troy | Michigan | 48098 | — |
| StudyMetrix Research | City of Saint Peters | Missouri | 63303 | — |
| Alliance for Multispecialty Research, LLC | Kansas City | Missouri | 64114 | — |
| Clinvest Headlands Llc | Springfield | Missouri | 65807 | — |
| Mercury Street Medical Group, PLLC | Butte | Montana | 59701 | — |
| Boeson Research MSO | Missoula | Montana | 59804 | — |
| Henderson Clinical Trials | Henderson | Nevada | 89052 | — |
| DaVita Clinical Research - Las Vegas | Las Vegas | Nevada | 89107 | — |
| Excel Clinical Research, LLC | Las Vegas | Nevada | 89109 | — |
| Alliance for Multispecialty Research, LLC | Las Vegas | Nevada | 89119 | — |
| Advanced Biomedical Research of America - South Eastern Avenue | Las Vegas | Nevada | 89123 | — |
| Vector Clinical Trials | Las Vegas | Nevada | 89128 | — |
| Albany Medical College, Division of Community Endocrinology | Albany | New York | 12203 | — |
| Capital Cardiology Associates | Albany | New York | 12211 | — |
| Westchester Medical Center Advanced Physicians Service | Kingston | New York | 12401 | — |
| St. Francis Hospital & Heart Center | New Hyde Park | New York | 11576 | — |
| NYU Langone Health | New York | New York | 10016 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| Saratoga Clinical Research | Saratoga Springs | New York | 12866 | — |
| Care Access - Fayetteville | Fayetteville | North Carolina | 28314 | — |
| Medication Management | Greensboro | North Carolina | 27405 | — |
| Physician's East Endocrinology | Greenville | North Carolina | 27834 | — |
| IMA Clinical Research - Lenoir | Lenoir | North Carolina | 28645 | — |
| West Clinical Research | Morehead City | North Carolina | 28557 | — |
| Accellacare - Raleigh | Raleigh | North Carolina | 27609 | — |
| Accellacare - Wilmington - 1917 Tradd Court | Wilmington | North Carolina | 28401 | — |
| Advanced Medical Research | Maumee | Ohio | 43537 | — |
| Alliance for Multispecialty Research, LLC | Norman | Oklahoma | 73069 | — |
| Heritage Valley Multispecialty Group, Inc | Beaver | Pennsylvania | 15009 | — |
| Northeast Clinical Research Center | Bethlehem | Pennsylvania | 18017 | — |
| Capital Area Research, LLC | Camp Hill | Pennsylvania | 17011 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822 | — |
| Lancaster General Hospital | Lancaster | Pennsylvania | 17602 | — |
| Clinical Renal Associates Ltd. | Media | Pennsylvania | 19063 | — |
| Clinical Research of Philadelphia | Philadelphia | Pennsylvania | 19114 | — |
| Tristar Clinical Investigations | Philadelphia | Pennsylvania | 19114 | — |
| Preferred Primary Care Physicians, Preferred Clinical Research-St. Clair | Pittsburgh | Pennsylvania | 15243 | — |
| Guthrie Medical Group, P.C. | Sayre | Pennsylvania | 18840 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Walker Family Care | Little River | South Carolina | 29566 | — |
| Care Access - Mauldin | Mauldin | South Carolina | 29662 | — |
| Circle Clinical Research | Sioux Falls | South Dakota | 57104 | — |
| Alliance for Multispecialty Research, LLC | Knoxville | Tennessee | 37920 | — |
| Care Access - Memphis 2 | Memphis | Tennessee | 38119 | — |
| IMA Clinical Research Austin | Austin | Texas | 78745 | — |
| Headlands Research - Brownsville | Brownsville | Texas | 78526 | — |
| South Texas Clinical Research | Corpus Christi | Texas | 78404 | — |
| Private Practice - Dr. Osvaldo A. Brusco | Corpus Christi | Texas | 78414 | — |
| Baylor Soltero CV Research Center | Dallas | Texas | 75226 | — |
| Velocity Clinical Research, Dallas | Dallas | Texas | 75230 | — |
| North Texas Endocrine Center | Dallas | Texas | 75231 | — |
| Renal Disease Research Institute | Dallas | Texas | 75246 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390-9302 | — |
| Soma Clinical Trials | Denison | Texas | 75020 | — |
| South Texas Research Institute | Edinburg | Texas | 78539 | — |
| Medresearch Inc | El Paso | Texas | 79902-4646 | — |
| Diabetes and Thyroid Center of Ft. Worth | Fort Worth | Texas | 76132 | — |
| Valley Institute of Research - Fort Worth | Fort Worth | Texas | 76164 | — |
| Juno Research | Houston | Texas | 77040 | — |
| Biopharma Informatic, LLC | Houston | Texas | 77043 | — |
| Aqua Research Institute | Houston | Texas | 77058 | — |
| Northwest Houston Cardiology - Cypress | Houston | Texas | 77070 | — |
| Clinical Trial Network | Houston | Texas | 77074 | — |
| PlanIt Research, PLLC | Houston | Texas | 77079 | — |
| Biopharma Informatic, LLC | Houston | Texas | 77084 | — |
| Research Physicians Network, LLC | Houston | Texas | 77089 | — |
| Accurate Clinical Research, Inc | Humble | Texas | 77346 | — |
| Texas Institute for Kidney and Endocrine Disorders | Lufkin | Texas | 75904 | — |
| Wellness Clinical Research | McKinney | Texas | 75069 | — |
| Revival Research Institute, LLC | McKinney | Texas | 75071 | — |
| PRX Research | Mesquite | Texas | 75149 | — |
| Southern Endocrinology Associates | Mesquite | Texas | 75149 | — |
| Clinical Advancement Center | San Antonio | Texas | 78212 | — |
| Discovery Clinical Trials - San Antonio | San Antonio | Texas | 78229 | — |
| IMA Clinical Research San Antonio | San Antonio | Texas | 78229 | — |
| Endeavor Clinical Trials | San Antonio | Texas | 78240 | — |
| DaVita Clinical Research - North Houston | Shenandoah | Texas | 77384 | — |
| Medrasa Clinical Research | Wylie | Texas | 75098 | — |
| Alpine Research Organization | Clinton | Utah | 84015 | — |
| Alliance for Multispecialty Research, LLC | Layton | Utah | 84041 | — |
| Synexus Clinical Research US, Inc. | Salt Lake City | Utah | 84106 | — |
| Utah Kidney Research Institute | Salt Lake City | Utah | 84115 | — |
| Alliance for Multispecialty Research, LLC | Norfolk | Virginia | 23502 | — |
| Dominion Medical Associates, Inc. | Richmond | Virginia | 23219 | — |
| Eastside Research Associates | Redmond | Washington | 98052 | — |
| Universal Research Group | Tacoma | Washington | 98405 | — |
| IMA Clinical Research West Virginia | Morgantown | West Virginia | 26505 | — |
| St. Vincent Hospital d/b/a Prevea Health | Green Bay | Wisconsin | 54303 | — |
| Clinical Investigation Specialists | Kenosha | Wisconsin | 53144 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 539 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06383390, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 19, 2026 · Synced May 4, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06383390 live on ClinicalTrials.gov.