Phase III Long-Term Extension Study With Dexpramipexole
Public ClinicalTrials.gov record NCT06388889. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label Long-Term Phase III Extension Study to Assess the Long-Term Safety and Tolerability of Dexpramipexole in Participants With Severe Eosinophilic Asthma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The goal of this clinical trial\] is to evaluate the long term safety of dexpramipexole treatment in participants with severe asthma, aged ≥18 years, on Global Initiative for Asthma (GINA) 2021 \[GINA, 2021\] Step 4 or 5 therapy and who completed either of the Phase III studies EXHALE-2 or EXHALE-3.
Study identification
- NCT ID
- NCT06388889
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 509 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 99 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 11, 2024
- Primary completion
- Dec 7, 2025
- Completion
- Dec 7, 2025
- Last update posted
- Dec 14, 2025
2024 – 2025
United States locations
- U.S. sites
- 23
- U.S. states
- 9
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site 20001-374 | Bakersfield | California | 93301 | — |
| Research Site 20001-376 | Northridge | California | 91324 | — |
| Research Site 20001-029 | Coral Gables | Florida | 33134 | — |
| Research Site 20001-014 | Greenacres City | Florida | 33467 | — |
| Research Site 30001-291 | Jacksonville | Florida | 32216 | — |
| Research Site 20001-066 | Miami | Florida | 33126 | — |
| Research Site 20001-001 | Miami | Florida | 33135 | — |
| Research Site 20001-311 | Miami | Florida | 33144 | — |
| Research Site 20001-026 | Miami | Florida | 33155 | — |
| Research Site 30001-082 | Miami | Florida | 33179 | — |
| Research Site 20001-024 | Miami | Florida | 33184 | — |
| Research Site 20054-024 | Miami | Florida | 33184 | — |
| Research Site 30001-429 | Plantation | Florida | 33137 | — |
| Research Site 30001-429 | Plantation | Florida | 33317 | — |
| Research Site 20001-004 | Tampa | Florida | 33607 | — |
| Research Site 20001-036 | Elwood | Indiana | 46036 | — |
| Research Site 20001-044 | Evansville | Indiana | 47715 | — |
| Research Site 20001-006 | Flint | Michigan | 48504 | — |
| Research Site 20001-046 | St Louis | Missouri | 63110 | — |
| Research Site 20001-355 | Toms River | New Jersey | 08755 | — |
| Research Site 20001-047 | Hawthorne | New York | 10532 | — |
| Research Site 20001-063 | Toledo | Ohio | 43617 | — |
| Research Site 30001-297 | Pearland | Texas | 77584 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 80 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06388889, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 14, 2025 · Synced Sep 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06388889 live on ClinicalTrials.gov.