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Completed Phase 2 Interventional

Effects of NNC0194-0499, Cagrilintide, and Semaglutide Alone or in Combinations on Liver Damage and Alcohol Use in People With Alcohol-related Liver Disease

ClinicalTrials.gov ID: NCT06409130

Public ClinicalTrials.gov record NCT06409130. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 11, 2026, 9:27 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Effects of NNC0194-0499 Alone and in Combination With Semaglutide, of Semaglutide Alone, and of Cagrilintide Alone and in Combination With Semaglutide on Liver Damage and Alcohol Use in People With Alcohol-related Liver Disease

Study identification

NCT ID
NCT06409130
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Novo Nordisk A/S
Industry
Enrollment
270 participants

Conditions and interventions

Interventions

  • Cagrilintide Drug
  • Cagrilintide + semaglutide Drug
  • Cagrilintide placebo Drug
  • NNC0194-0499 Drug
  • NNC0194-0499 placebo Drug
  • Semaglutide Drug
  • Semaglutide placebo (Group A) Drug
  • Semaglutide placebo (Group B) Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 19, 2024
Primary completion
Nov 20, 2025
Completion
Jan 11, 2026
Last update posted
Mar 11, 2026

2024 – 2026

United States locations

U.S. sites
29
U.S. states
13
U.S. cities
26
Facility City State ZIP Site status
The Institute for Liver Health Chandler Arizona 85224
Arizona Liver Center Tucson Arizona 85712
Del Sol Research Management, LLC Tucson Arizona 85715
OM Research LLC Lancaster California 93534
California Liver Research Institute Pasadena California 91105
Covenant Metabolic Specialists LLC Fort Myers Florida 33912
Miguel Rebollar PA Hialeah Florida 33012
UF Hlth Jacksonville Jacksonville Florida 32224
Univ of Miami/Schiff Ctr Miami Florida 33136
Covenant Metabolic Specialists LLC University Park Florida 34201
Rush University Med. Cntr Chicago Illinois 60612
Kansas Medical Clinic, PA Topeka Kansas 66606
Louisiana Research Center, LLC Shreveport Louisiana 71105
Boston Medical Center_Cary Boston Massachusetts 02118
Mayo Clinic Rochester Rochester Minnesota 55902
Jubilee Clinical Research, Inc. Las Vegas Nevada 89106
DSI Research,LLC Springboro Ohio 45066
University of Pennsylvania Hospital Philadelphia Pennsylvania 19104
UPMC_Center for Liver Care Pittsburgh Pennsylvania 15213
Digestive Health Research, TN Hermitage Tennessee 37076
Texas Clinical Research Institute Arlington Texas 76012
The Liver Institute Dallas Texas 75203
South Texas Research Institute Edinburg Texas 78539
Baylor St. Luke's Medical Center Houston Texas 77030
Houston Research Institute Houston Texas 77079
Amer. Rrsch Corp-TX Liver Inst San Antonio Texas 78215
Pinnacle Clinical Research San Antonio Texas 78229
Liver Specialists of Texas Sugar Land Texas 77479
Velocity Clinical Res, Waco Waco Texas 76710

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 73 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06409130, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 11, 2026 · Synced May 11, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06409130 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →