Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis
Public ClinicalTrials.gov record NCT06414954. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b, Randomised, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of 3 Dose Levels of NMD670 Over 21 Days in Adult Patients With AChR/MuSK-Ab+ Myasthenia Gravis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This Phase 2 proof-of-concept, dose range finding study aims to evaluate the safety and efficacy of 3 dose levels of NMD670 vs placebo in adult patients with MG with antibodies against AChR or MuSK, administered twice a day (BID) for 21 days.
Study identification
- NCT ID
- NCT06414954
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 84 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 15, 2024
- Primary completion
- Nov 30, 2026
- Completion
- Nov 30, 2026
- Last update posted
- Aug 20, 2026
2024 – 2026
United States locations
- U.S. sites
- 11
- U.S. states
- 9
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Profound Research LLC | Carlsbad | California | 92011 | Withdrawn |
| University of California Irvine Medical Center | Irvine | California | 92868 | Recruiting |
| University of Colorado Neuromuscular Division | Aurora | Colorado | 80045 | Recruiting |
| SFM Clinical Research, LLC | Boca Raton | Florida | 33487 | Recruiting |
| Neuromuscular Research Division | University of South Florida | Tampa | Florida | 33612 | Recruiting |
| Augusta University, Neuroscience Center | Augusta | Georgia | 30912 | Recruiting |
| NextGen Precision Health | Columbia | Missouri | 65212 | Recruiting |
| The University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599 | Recruiting |
| The Ohio State University | Columbus | Ohio | 43221 | Recruiting |
| University of Oregon | Portland | Oregon | 97239 | Recruiting |
| Semmes Murphey Clinic | Memphis | Tennessee | 38120 | Withdrawn |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 29 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06414954, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 20, 2026 · Synced Sep 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06414954 live on ClinicalTrials.gov.