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Completed Phase 2 Interventional

Vonafexor ALPort Syndrome Efficacy & Safety TRIAl-1 (ALPESTRIA-1)

ClinicalTrials.gov ID: NCT06425055

Public ClinicalTrials.gov record NCT06425055. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 6:40 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Vonafexor Fixed Dose-escalation Safety and Proof-of-concept Study in Patients With at Risk of Progression Alport Syndrome

Study identification

NCT ID
NCT06425055
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Enyo Pharma
Industry
Enrollment
26 participants

Conditions and interventions

Interventions

  • Vonafexor Drug

Drug

Eligibility (public fields only)

Age range
16 Years to 55 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 31, 2024
Primary completion
Sep 3, 2025
Completion
Nov 19, 2025
Last update posted
Feb 8, 2026

2024 – 2025

United States locations

U.S. sites
7
U.S. states
7
U.S. cities
7
Facility City State ZIP Site status
Dr Eric Wallace - University of Alabama Birmingham Alabama 35294
Dr Anjay Rastogi - UCLA Health, David Geffen School of Medicine Los Angeles California 90095
Dr Arnold Silva - Boise Kidney & Hypertension Boise Idaho 83703
Dr Suneel Udani - NANI Research Hinsdale Illinois 60521
Dr Tingting Li - Washington University St Louis Missouri 63110
Dr James Simon - Cleveland Clinic Foundation Cleveland Ohio 44195
Dr Ankit Mehta - Renal Disease Research Institute Dallas Texas 75126

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06425055, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 8, 2026 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06425055 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →