Clinical Data Registry of Amblyopia Patients on Luminopia Treatment
Public ClinicalTrials.gov record NCT06429280. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Amblyopia is the most prevalent cause of reduced monocular visual acuity in children and young adults, with estimates of prevalence ranging from 1% to 5%. The most common associated amblyogenic risk factors are uncorrected anisometropia, strabismus, or a combination of these. In addition to reduced visual acuity, amblyopic patients may also have measurable dysfunction of accommodation, fixation, binocularity, vergence, reading fluency, depth perception, and contrast sensitivity. For the first time since the incorporation of atropine penalization into amblyopia management, physicians can now offer Luminopia, an FDA-approved dual action dichoptic treatment, to patients with amblyopia. Since the product became commercially available in November 2022, the number of patients on Luminopia therapy continues to grow. This presents a unique opportunity to gather real world evidence from a large number of patients, representative of how ophthalmologists and optometrists are applying this novel treatment in the real world. A registry of the clinical data associated with Luminopia treatment, with IRB oversight, will provide answers to key scientific questions using a large dataset.
Study identification
- NCT ID
- NCT06429280
- Recruitment status
- Recruiting
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 500 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 31, 2023
- Primary completion
- Dec 30, 2026
- Completion
- Dec 30, 2026
- Last update posted
- Sep 11, 2025
2023 – 2026
United States locations
- U.S. sites
- 13
- U.S. states
- 10
- U.S. cities
- 13
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCSF Benioff Children's Physicians | San Ramon | California | 94583 | Recruiting |
| Sansum Clinic | Santa Barbara | California | 93110 | Recruiting |
| Okaloosa Ophthalmology | Crestview | Florida | 32536 | Recruiting |
| Family Focus Eye Care | Gainsville | Florida | 32605 | Recruiting |
| Eye Physicians of Central Florida | Maitland | Florida | 32751 | Recruiting |
| Children's Eye Institute of Savannah | Savannah | Georgia | 31406 | Recruiting |
| Honolulu Eye Clinic | Honolulu | Hawaii | 96813 | Recruiting |
| Lurie Children's Hospital | Chicago | Illinois | 60611 | Recruiting |
| Riley Children's Hospital at IU Health | Indianapolis | Indiana | 46202 | Recruiting |
| Nevada Eye Physicians | Las Vegas | Nevada | 89149 | Recruiting |
| Concord Eye Center | Concord | New Hampshire | 03301 | Recruiting |
| Children's Hospital Of Philadelphia | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Pediatric Eye Specialist | Fort Worth | Texas | 76104 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06429280, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 11, 2025 · Synced Sep 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06429280 live on ClinicalTrials.gov.