To Evaluate the Effects of NMRA-335140 on Symptoms of Major Depression in Participants With Bipolar II Disorder.
Public ClinicalTrials.gov record NCT06429722. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a, Randomized, Double-blind, Placebo-controlled Pilot Study to Evaluate the Effects of Oral NMRA-335140 Versus Placebo in Participants With a Major Depressive Episode Associated With Bipolar II Disorder
Study identification
- NCT ID
- NCT06429722
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Neumora Therapeutics, Inc.
- Industry
- Enrollment
- 18 participants
Conditions and interventions
Interventions
- NMRA-335140 80 mg Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 12, 2024
- Primary completion
- Apr 8, 2025
- Completion
- May 29, 2025
- Last update posted
- Mar 29, 2026
2024 – 2025
United States locations
- U.S. sites
- 21
- U.S. states
- 11
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Neumora Investigator Site | Phoenix | Arizona | 85012 | — |
| Neumora Investigator Site | Little Rock | Arkansas | 72211 | — |
| Neumora Investigator Site | Garden Grove | California | 92845 | — |
| Neumora Investigator Site | Long Beach | California | 90807 | — |
| Neumora Investigator Site | San Jose | California | 95124 | — |
| Neumora Investigator Site | Torrance | California | 90504 | — |
| Neumora Investigator Site | Gainesville | Florida | 32607 | — |
| Neumora Investigator Site | Lauderhill | Florida | 33161 | — |
| Neumora Investigator Site | Maitland | Florida | 32751 | — |
| Neumora Investigator Site | Miami | Florida | 33122 | — |
| Neumora Investigator Site | Miami Lakes | Florida | 33016 | — |
| Neumora Investigator Site | Marietta | Georgia | 30060 | — |
| Neumora Investigator Site | Savannah | Georgia | 31405 | — |
| Neumora Investigator Site | Watertown | Massachusetts | 02472 | — |
| Neumora Investigator Site | Flowood | Mississippi | 39232 | — |
| Neumora Investigator Site | Marlton | New Jersey | 08053 | — |
| Neumora Investigator Site | Princeton | New Jersey | 08540 | — |
| Neumora Investigator Site | Toms River | New Jersey | 08755 | — |
| Neumora Investigator Site | Brooklyn | New York | 11229 | — |
| Neumora Investigator Site | Houston | Texas | 77030 | — |
| Neumora Investigator Site | Bellevue | Washington | 98007 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06429722, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 29, 2026 · Synced May 18, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06429722 live on ClinicalTrials.gov.