A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)
Public ClinicalTrials.gov record NCT06455202. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Barzolvolimab in Patients With Chronic Spontaneous Urticaria Who Remain Symptomatic Despite H1 Antihistamine Treatment (EMBARQ-CSU2)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to establish the efficacy, safety and tolerability of barzolvolimab in adult participants with Chronic Spontaneous Urticaria (CSU) inadequately controlled by non-sedating second generation H1-antihistamines in comparison to placebo.
Study identification
- NCT ID
- NCT06455202
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 976 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 19, 2024 (Actual)
- Primary completion
- Oct 2026 (Estimated)
- Completion
- Apr 2027 (Estimated)
- Last update posted
- Mar 25, 2026
2024 – 2027
United States locations
- U.S. sites
- 63
- U.S. states
- 24
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Allervie Clinical Research - Cullman | Cullman | Alabama | 35058 | — |
| Research Solutions of Arizona PC | Litchfield Park | Arizona | 85340 | — |
| Medical Research of Arizona a division of Allergy, Asthma, & Immunology, Assoc. Ltd. | Scottsdale | Arizona | 85258 | — |
| Center for Dermatology & Plastic Surgery | Scottsdale | Arizona | 85260 | — |
| Kern Research, Inc. | Bakersfield | California | 93301 | — |
| UCLA Clinical Trials Contracts & Strategic Relations | Los Angeles | California | 90024 | — |
| California Allergy and Asthma Medical Group | Los Angeles | California | 90025 | — |
| LA Universal Research Center, Inc. | Los Angeles | California | 90057 | — |
| Allergy and Asthma Associates of Southern Cal | Mission Viejo | California | 92691 | — |
| Huntington Asthma & Allergy Center | Pasadena | California | 91107 | — |
| Apex Clinical Research | San Diego | California | 92120 | — |
| WR-MCCR | San Diego | California | 92120 | — |
| University Clinical Trials | San Diego | California | 92123 | — |
| Clinical Science Institute | Santa Monica | California | 90404 | — |
| Raffi Tachdjian MD, Inc | Santa Monica | California | 90404 | — |
| Clarity Dermatology, PLLC | Castle Rock | Colorado | 80109 | — |
| Asthma and Allergy Associates | Colorado Springs | Colorado | 80907 | — |
| Driven Research LLC | Coral Gables | Florida | 33134 | — |
| Palm Beach Dermatology Group | Delray Beach | Florida | 33484 | — |
| Dolphin Medical Research | Doral | Florida | 33172 | — |
| South FL Clinical Research LLC | Miami | Florida | 33165 | — |
| Dade Florida Clinical Research Center | Miami | Florida | 33173 | — |
| Deluxe Health Center | Miami Lakes | Florida | 33014 | — |
| Revival Clinical Research | Orlando | Florida | 32807 | — |
| International Clinical Research - FL LLC | Sanford | Florida | 32771 | — |
| D&H Tamarac Research Center, LLC | Tamarac | Florida | 33321 | — |
| Advanced Clinical Research Institute (ACRI) - Florida | Tampa | Florida | 33607 | — |
| Deluxe Health Center | Tampa | Florida | 33607 | — |
| MOORE Clinical Research, Inc. d/b/a TrueBlue Clinical Research | Tampa | Florida | 33609 | — |
| University of South Florida | Tampa | Florida | 33613 | — |
| Olympian Clinical Research | Tampa | Florida | 33615 | — |
| Lane Dermatology Research - Centricity - PPDS | Columbus | Georgia | 31904 | — |
| Skin Care Physicians of Georgia | Macon | Georgia | 31217 | — |
| Treasure Valley Medical Research | Boise | Idaho | 83706 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Sneeze Wheeze and Itch Associates LLC | Normal | Illinois | 61761 | — |
| The Indiana Clinical Trials Center, PC | Plainfield | Indiana | 46168 | — |
| South Bend Clinic | South Bend | Indiana | 46617 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160-8500 | — |
| Equity Medical | Bowling Green | Kentucky | 42104 | — |
| Allergy & Asthma Associates | Lexington | Kentucky | 40509 | — |
| Velocity Clinical Research - The Dermatology Clinic - Baton Rouge - PPDS | Baton Rouge | Louisiana | 70808 | — |
| Continental Clinical Research Solutions, LLC - ClinEdge - PPDS | Towson | Maryland | 21204 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Derm Institute of Western Michigan | Caledonia | Michigan | 49316 | — |
| Clarkston Skin Research - Clarkston | Clarkston | Michigan | 48346 | — |
| Midwest Clinical Research, LLC | St Louis | Missouri | 63141 | — |
| Washington University School of Medicine | St Louis | Missouri | 63141 | — |
| Skin Specialists PC | Omaha | Nebraska | 68144 | — |
| Hudson-Essex Allergy | Belleville | New Jersey | 07109 | — |
| Impact Medical / Circuit Clinical | Paramus | New Jersey | 07652 | — |
| Impact Medical / Circuit Clinical | Riverdale | New Jersey | 07457 | — |
| Equity Medical LLC | New York | New York | 10023 | — |
| OptiSkin Medical | New York | New York | 10128 | — |
| Optima Research | Boardman | Ohio | 44512 | — |
| Optimed Research Ltd - ClinEdge - PPDS | Columbus | Ohio | 43235 | — |
| Penn State Health Milton Hershey Med Cen | Hershey | Pennsylvania | 17033 | — |
| Clinical Partners LLC | Johnston | Rhode Island | 02919 | — |
| Western Sky Medical Research | El Paso | Texas | 79932 | — |
| Austin Institute for Clinical Research, Inc. | Pflugerville | Texas | 78660 | — |
| Rainey & Finklea San Antonio Dermatology | San Antonio | Texas | 78213 | — |
| Allergy Associates of Utah - Sandy | Murray | Utah | 84107 | — |
| Kalo Clinical Research | West Valley City | Utah | 84120 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 182 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06455202, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 25, 2026 · Synced Oct 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06455202 live on ClinicalTrials.gov.