Amplitude Vascular Systems (AVS) Lithotripsy POWER PAD 2 Trial
Public ClinicalTrials.gov record NCT06457685. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Pulse Intravascular Lithotripsy™ (Pulse IVL™) to Open Vessels With Calcific Walls and Enhance Vascular Compliance and Remodeling for Peripheral Artery Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
POWER PAD 2 is a prospective, single-arm, multicenter, non-randomized clinical study designed to demonstrate the safety and effectiveness of the Amplitude Vascular Systems (AVS) Pulse Intravascular Lithotripsy™ (Pulse IVL™) System for treatment of calcified (moderate to severe), stenotic, superficial femoral and popliteal arteries in patients with peripheral arterial disease.
Study identification
- NCT ID
- NCT06457685
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 115 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 5, 2024 (Actual)
- Primary completion
- Mar 2026 (Estimated)
- Completion
- Aug 2026 (Estimated)
- Last update posted
- Feb 18, 2026
2024 – 2026
United States locations
- U.S. sites
- 19
- U.S. states
- 13
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arkansas Heart Hospital | Little Rock | Arkansas | 72022 | — |
| Vascular and Interventional Specialists of Orange County | Orange | California | 92868 | — |
| Advanced Heart and Vein Center | Thornton | Colorado | 80023 | — |
| Piedmont Heart Institute | Atlanta | Georgia | 30309 | — |
| Midwest Cardiovascular Research Foundation | Davenport | Iowa | 52802 | — |
| Mercy Hospital South | St Louis | Missouri | 63128 | — |
| Advanced Endovascular Physicians | West Orange | New Jersey | 07052 | — |
| NYU Langone | New York | New York | 10016 | — |
| Mount Sinai | New York | New York | 10029 | — |
| Columbia University and New York Presbyterian Hospital (NYPH) | New York | New York | 10032 | — |
| NC Heart and Vascular Research | Raleigh | North Carolina | 27607 | — |
| The Christ Hospital | Cincinnati | Ohio | 45219 | — |
| University Hospital- Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| OhioHealth Riverside | Columbus | Ohio | 43214 | — |
| Mainline Health Lankenau | Bryn Mawr | Pennsylvania | 19010 | — |
| UPMC Pinnacle | Mechanicsburg | Pennsylvania | 17050 | — |
| The Miriam Hospital - Brown University Health Partner | Providence | Rhode Island | 02906 | — |
| Ascension Seton | Austin | Texas | 78723 | — |
| The Heart Hospital Baylor Plano | Plano | Texas | 75093 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06457685, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 18, 2026 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06457685 live on ClinicalTrials.gov.