A Clinical Study of Efinopegdutide in People With Compensated Cirrhosis Due to Steatohepatitis (MK-6024-017)
Public ClinicalTrials.gov record NCT06465186. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 2a Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Efinopegdutide (MK-6024) in Adults With Compensated Cirrhosis Secondary to Metabolic Dysfunction-Associated Steatohepatitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Researchers are looking for ways to treat a type of liver disease caused by elevated liver fat, called metabolic dysfunction-associated steatohepatitis (MASH). MASH was formerly called non-alcoholic steatohepatitis (NASH). Researchers want to learn if a study medicine called efinopegdutide can treat MASH.The goals of this study are to learn: * If efinopegdutide can lower the amount of fat, inflammation, and scarring (fibrosis) in the liver * About the safety of efinopegdutide and how well people tolerate it
Study identification
- NCT ID
- NCT06465186
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 85 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 12, 2024 (Actual)
- Primary completion
- Aug 3, 2026 (Actual)
- Completion
- Aug 3, 2026 (Actual)
- Last update posted
- Sep 21, 2026
2024 – 2026
United States locations
- U.S. sites
- 33
- U.S. states
- 13
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Institute for Liver Health II dba Arizona Clinical Trial-The Institute for Liver Health ( Site 0149) | Chandler | Arizona | 85224 | — |
| Arizona Clinical Trials ( Site 0158) | Flagstaff | Arizona | 86001 | — |
| The Institute for Liver Health II dba Arizona Liver Health - Peoria ( Site 0120) | Peoria | Arizona | 85381 | — |
| The Institute for Liver Health II dba Arizona Liver Health-Tucson ( Site 0111) | Tucson | Arizona | 85712 | — |
| California Liver Research Institute ( Site 0113) | Pasadena | California | 91105 | — |
| Acclaim Clinical Research ( Site 0137) | San Diego | California | 92120 | — |
| Velocity Clinical Research, Panorama City ( Site 0124) | Van Nuys | California | 91405 | — |
| Rocky Mountain Gastroenterology ( Site 0127) | Littleton | Colorado | 80120 | — |
| Synergy Healthcare ( Site 0118) | Bradenton | Florida | 34209 | — |
| Homestead Associates in Research, Inc. ( Site 0139) | Homestead | Florida | 33033 | — |
| Florida Research Institute ( Site 0116) | Lakewood Rch | Florida | 34211 | — |
| Floridian Clinical Research, LLC ( Site 0109) | Miami Lakes | Florida | 33016 | — |
| Southeast Clinical Research Center ( Site 0119) | Dalton | Georgia | 30720 | — |
| Delta Research Partners ( Site 0160) | Bastrop | Louisiana | 71220 | — |
| Louisiana Research Center ( Site 0161) | Shreveport | Louisiana | 71105 | — |
| Woodholme Gastroenterology Associates-Woodholme Gastroenterology Associates ( Site 0130) | Glen Burnie | Maryland | 21061 | — |
| Velocity Clinical Research Rockville ( Site 0143) | Rockville | Maryland | 20854 | — |
| Huron Gastroenterology ( Site 0102) | Ypsilanti | Michigan | 48197 | — |
| The Machuca Foundation ( Site 0115) | Las Vegas | Nevada | 89101 | — |
| Excel Clinical Research, LLC ( Site 0101) | Las Vegas | Nevada | 89109 | — |
| Southwest Gastroenterology Associates ( Site 0129) | Albuquerque | New Mexico | 87109 | — |
| Coastal Research Institute - Fayetteville ( Site 0159) | Fayetteville | North Carolina | 28304 | — |
| Lucas Research, Inc ( Site 0105) | Morehead City | North Carolina | 28557 | — |
| Texas Clinical Research Institute ( Site 0126) | Arlington | Texas | 76012 | — |
| Pinnacle Clinical Research ( Site 0104) | Austin | Texas | 78757 | — |
| Pinnacle Clinical Research-Corpus Christi ( Site 0156) | Corpus Christi | Texas | 78404 | — |
| Zenos Clinical Research ( Site 0136) | Dallas | Texas | 75230 | — |
| GI Alliance Department of Research ( Site 0162) | Fort Worth | Texas | 76104 | — |
| Houston Research Institute ( Site 0172) | Houston | Texas | 77004 | — |
| Houston Research Institute ( Site 0117) | Houston | Texas | 77079 | — |
| American Research Corporation ( Site 0131) | San Antonio | Texas | 78215 | — |
| Pinnacle Clinical Research-Clinical Research Coordination ( Site 0125) | San Antonio | Texas | 78229 | — |
| University of Virginia Health System ( Site 0164) | Charlottesville | Virginia | 22908 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 35 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06465186, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 21, 2026 · Synced Oct 30, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06465186 live on ClinicalTrials.gov.