ClinicalTrials.gov record
Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body
ClinicalTrials.gov ID: NCT06470243
Public ClinicalTrials.gov record NCT06470243. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 9, 2026, 1:05 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Study of Cabazitaxel With or Without Carboplatin in Patients With Metastatic Castrate-Resistant Prostate Cancer (mCRPC), Stratified by Aggressive Variant Signature
Study identification
- NCT ID
- NCT06470243
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- SWOG Cancer Research Network
- Network
- Enrollment
- 528 participants
Conditions and interventions
Interventions
- Biospecimen Collection Procedure
- Bone Scan Procedure
- Cabazitaxel Drug
- Carboplatin Drug
- Chest Radiography Procedure
- Computed Tomography Procedure
- Magnetic Resonance Imaging Procedure
- Positron Emission Tomography Procedure
- Prednisone Drug
Procedure · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 26, 2024
- Primary completion
- Jun 29, 2029
- Completion
- Mar 31, 2034
- Last update posted
- Jan 21, 2026
2024 – 2034
United States locations
- U.S. sites
- 174
- U.S. states
- 24
- U.S. cities
- 132
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Highlands Oncology Group - Fayetteville | Fayetteville | Arkansas | 72703 | Recruiting |
| Highlands Oncology Group - Rogers | Rogers | Arkansas | 72758 | Recruiting |
| Highlands Oncology Group | Springdale | Arkansas | 72762 | Recruiting |
| Tibor Rubin VA Medical Center | Long Beach | California | 90822 | Recruiting |
| Beebe Medical Center | Lewes | Delaware | 19958 | Recruiting |
| Beebe South Coastal Health Campus | Millville | Delaware | 19967 | Recruiting |
| Helen F Graham Cancer Center | Newark | Delaware | 19713 | Recruiting |
| Medical Oncology Hematology Consultants PA | Newark | Delaware | 19713 | Recruiting |
| Christiana Care Health System-Christiana Hospital | Newark | Delaware | 19718 | Recruiting |
| Beebe Health Campus | Rehoboth Beach | Delaware | 19971 | Recruiting |
| Christiana Care Health System-Wilmington Hospital | Wilmington | Delaware | 19801 | Recruiting |
| Holy Cross Hospital | Fort Lauderdale | Florida | 33308 | Recruiting |
| Saint Alphonsus Cancer Care Center-Boise | Boise | Idaho | 83706 | Recruiting |
| Saint Alphonsus Cancer Care Center-Caldwell | Caldwell | Idaho | 83605 | Recruiting |
| Kootenai Health - Coeur d'Alene | Coeur d'Alene | Idaho | 83814 | Recruiting |
| Idaho Urologic Institute-Meridian | Meridian | Idaho | 83642 | Recruiting |
| Saint Alphonsus Cancer Care Center-Nampa | Nampa | Idaho | 83687 | Recruiting |
| Kootenai Clinic Cancer Services - Post Falls | Post Falls | Idaho | 83854 | Recruiting |
| Kootenai Clinic Cancer Services - Sandpoint | Sandpoint | Idaho | 83864 | Recruiting |
| Illinois CancerCare-Bloomington | Bloomington | Illinois | 61704 | Recruiting |
| Illinois CancerCare-Canton | Canton | Illinois | 61520 | Recruiting |
| Memorial Hospital of Carbondale | Carbondale | Illinois | 62902 | Recruiting |
| SIH Cancer Institute | Carterville | Illinois | 62918 | Recruiting |
| Illinois CancerCare-Carthage | Carthage | Illinois | 62321 | Recruiting |
| Centralia Oncology Clinic | Centralia | Illinois | 62801 | Recruiting |
| Northwestern University | Chicago | Illinois | 60611 | Recruiting |
| University of Illinois | Chicago | Illinois | 60612 | Recruiting |
| Northwestern Medicine Cancer Center Kishwaukee | DeKalb | Illinois | 60115 | Recruiting |
| Cancer Care Specialists of Illinois - Decatur | Decatur | Illinois | 62526 | Recruiting |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | Recruiting |
| Illinois CancerCare-Dixon | Dixon | Illinois | 61021 | Recruiting |
| Crossroads Cancer Center | Effingham | Illinois | 62401 | Recruiting |
| Illinois CancerCare-Eureka | Eureka | Illinois | 61530 | Recruiting |
| Illinois CancerCare-Galesburg | Galesburg | Illinois | 61401 | Recruiting |
| Western Illinois Cancer Treatment Center | Galesburg | Illinois | 61401 | Recruiting |
| Northwestern Medicine Cancer Center Delnor | Geneva | Illinois | 60134 | Recruiting |
| Northwestern Medicine Glenview Outpatient Center | Glenview | Illinois | 60026 | Recruiting |
| Northwestern Medicine Grayslake Outpatient Center | Grayslake | Illinois | 60030 | Recruiting |
| Illinois CancerCare-Kewanee Clinic | Kewanee | Illinois | 61443 | Recruiting |
| Northwestern Medicine Lake Forest Hospital | Lake Forest | Illinois | 60045 | Recruiting |
| Illinois CancerCare-Macomb | Macomb | Illinois | 61455 | Recruiting |
| Cancer Care Center of O'Fallon | O'Fallon | Illinois | 62269 | Recruiting |
| HSHS Saint Elizabeth's Hospital | O'Fallon | Illinois | 62269 | Recruiting |
| Northwestern Medicine Orland Park | Orland Park | Illinois | 60462 | Recruiting |
| Illinois CancerCare-Ottawa Clinic | Ottawa | Illinois | 61350 | Recruiting |
| Illinois CancerCare-Pekin | Pekin | Illinois | 61554 | Recruiting |
| Illinois CancerCare-Peoria | Peoria | Illinois | 61615 | Recruiting |
| Methodist Medical Center of Illinois | Peoria | Illinois | 61636 | Recruiting |
| Illinois CancerCare-Peru | Peru | Illinois | 61354 | Recruiting |
| Valley Radiation Oncology | Peru | Illinois | 61354 | Recruiting |
| Illinois CancerCare-Princeton | Princeton | Illinois | 61356 | Recruiting |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62702 | Recruiting |
| Springfield Clinic | Springfield | Illinois | 62702 | Recruiting |
| Memorial Medical Center | Springfield | Illinois | 62781 | Recruiting |
| Northwestern Medicine Cancer Center Warrenville | Warrenville | Illinois | 60555 | Recruiting |
| Illinois CancerCare - Washington | Washington | Illinois | 61571 | Recruiting |
| Reid Health | Richmond | Indiana | 47374 | Recruiting |
| Mercy Hospital | Cedar Rapids | Iowa | 52403 | Recruiting |
| Oncology Associates at Mercy Medical Center | Cedar Rapids | Iowa | 52403 | Recruiting |
| Christiana Care - Union Hospital | Elkton | Maryland | 21921 | Recruiting |
| Trinity Health Saint Joseph Mercy Hospital Ann Arbor | Ann Arbor | Michigan | 48106 | Recruiting |
| Trinity Health IHA Medical Group Hematology Oncology - Brighton | Brighton | Michigan | 48114 | Recruiting |
| Trinity Health Medical Center - Brighton | Brighton | Michigan | 48114 | Recruiting |
| Trinity Health IHA Medical Group Hematology Oncology - Canton | Canton | Michigan | 48188 | Recruiting |
| Trinity Health Medical Center - Canton | Canton | Michigan | 48188 | Recruiting |
| Caro Cancer Center | Caro | Michigan | 48723 | Recruiting |
| Chelsea Hospital | Chelsea | Michigan | 48118 | Recruiting |
| Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital | Chelsea | Michigan | 48118 | Recruiting |
| Hematology Oncology Consultants-Clarkston | Clarkston | Michigan | 48346 | Recruiting |
| Newland Medical Associates-Clarkston | Clarkston | Michigan | 48346 | Recruiting |
| Henry Ford Health Saint John Hospital | Detroit | Michigan | 48236 | Recruiting |
| Great Lakes Cancer Management Specialists-Doctors Park | East China Township | Michigan | 48054 | Recruiting |
| Genesee Cancer and Blood Disease Treatment Center | Flint | Michigan | 48503 | Recruiting |
| Genesee Hematology Oncology PC | Flint | Michigan | 48503 | Recruiting |
| Genesys Hurley Cancer Institute | Flint | Michigan | 48503 | Recruiting |
| Hurley Medical Center | Flint | Michigan | 48503 | Recruiting |
| Great Lakes Cancer Management Specialists-Van Elslander Cancer Center | Grosse Pointe Woods | Michigan | 48236 | Recruiting |
| Henry Ford Saint John Hospital - Academic | Grosse Pointe Woods | Michigan | 48236 | Recruiting |
| Henry Ford Saint John Hospital - Breast | Grosse Pointe Woods | Michigan | 48236 | Recruiting |
| University of Michigan Health - Sparrow Lansing | Lansing | Michigan | 48912 | Recruiting |
| Trinity Health Saint Mary Mercy Livonia Hospital | Livonia | Michigan | 48154 | Recruiting |
| Great Lakes Cancer Management Specialists-Macomb Medical Campus | Macomb | Michigan | 48044 | Recruiting |
| Henry Ford Warren Hospital - Breast Macomb | Macomb | Michigan | 48044 | Recruiting |
| Saint Mary's Oncology/Hematology Associates of Marlette | Marlette | Michigan | 48453 | Recruiting |
| Hope Cancer Center | Pontiac | Michigan | 48341 | Recruiting |
| Michigan Healthcare Professionals Pontiac | Pontiac | Michigan | 48341 | Recruiting |
| Newland Medical Associates-Pontiac | Pontiac | Michigan | 48341 | Recruiting |
| Trinity Health Saint Joseph Mercy Oakland Hospital | Pontiac | Michigan | 48341 | Recruiting |
| MyMichigan Medical Center Saginaw | Saginaw | Michigan | 48601 | Recruiting |
| Oncology Hematology Associates of Saginaw Valley PC | Saginaw | Michigan | 48604 | Recruiting |
| MyMichigan Medical Center Tawas | Tawas City | Michigan | 48764 | Recruiting |
| Great Lakes Cancer Management Specialists-Macomb Professional Building | Warren | Michigan | 48093 | Recruiting |
| Henry Ford Madison Heights Hospital - Breast | Warren | Michigan | 48093 | Recruiting |
| Saint John Macomb-Oakland Hospital | Warren | Michigan | 48093 | Recruiting |
| Saint Mary's Oncology/Hematology Associates of West Branch | West Branch | Michigan | 48661 | Recruiting |
| Huron Gastroenterology PC | Ypsilanti | Michigan | 48106 | Recruiting |
| Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus | Ypsilanti | Michigan | 48197 | Recruiting |
| Minnesota Oncology - Burnsville | Burnsville | Minnesota | 55337 | Recruiting |
| Cambridge Medical Center | Cambridge | Minnesota | 55008 | Recruiting |
| Mercy Hospital | Coon Rapids | Minnesota | 55433 | Recruiting |
| Fairview Southdale Hospital | Edina | Minnesota | 55435 | Recruiting |
| Fairview Clinics and Surgery Center Maple Grove | Maple Grove | Minnesota | 55369 | Recruiting |
| Minnesota Oncology Hematology PA-Maplewood | Maplewood | Minnesota | 55109 | Recruiting |
| Saint John's Hospital - Healtheast | Maplewood | Minnesota | 55109 | Recruiting |
| Abbott-Northwestern Hospital | Minneapolis | Minnesota | 55407 | Recruiting |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55415 | Recruiting |
| Health Partners Inc | Minneapolis | Minnesota | 55454 | Recruiting |
| Monticello Cancer Center | Monticello | Minnesota | 55362 | Recruiting |
| New Ulm Medical Center | New Ulm | Minnesota | 56073 | Recruiting |
| Fairview Northland Medical Center | Princeton | Minnesota | 55371 | Recruiting |
| North Memorial Medical Health Center | Robbinsdale | Minnesota | 55422 | Recruiting |
| Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | 55416 | Recruiting |
| Regions Hospital | Saint Paul | Minnesota | 55101 | Recruiting |
| United Hospital | Saint Paul | Minnesota | 55102 | Recruiting |
| Saint Francis Regional Medical Center | Shakopee | Minnesota | 55379 | Recruiting |
| Lakeview Hospital | Stillwater | Minnesota | 55082 | Recruiting |
| Ridgeview Medical Center | Waconia | Minnesota | 55387 | Recruiting |
| Rice Memorial Hospital | Willmar | Minnesota | 56201 | Recruiting |
| Minnesota Oncology Hematology PA-Woodbury | Woodbury | Minnesota | 55125 | Recruiting |
| Fairview Lakes Medical Center | Wyoming | Minnesota | 55092 | Recruiting |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | Recruiting |
| Saint Francis Medical Center | Cape Girardeau | Missouri | 63703 | Recruiting |
| Southeast Cancer Center | Cape Girardeau | Missouri | 63703 | Recruiting |
| Parkland Health Center - Farmington | Farmington | Missouri | 63640 | Recruiting |
| Sainte Genevieve County Memorial Hospital | Sainte Genevieve | Missouri | 63670 | Recruiting |
| Missouri Baptist Medical Center | St Louis | Missouri | 63131 | Recruiting |
| Missouri Baptist Sullivan Hospital | Sullivan | Missouri | 63080 | Recruiting |
| BJC Outpatient Center at Sunset Hills | Sunset Hills | Missouri | 63127 | Recruiting |
| Community Hospital of Anaconda | Anaconda | Montana | 59711 | Recruiting |
| Billings Clinic Cancer Center | Billings | Montana | 59101 | Recruiting |
| Bozeman Health Deaconess Hospital | Bozeman | Montana | 59715 | Recruiting |
| Benefis Sletten Cancer Institute | Great Falls | Montana | 59405 | Recruiting |
| Great Falls Clinic | Great Falls | Montana | 59405 | Recruiting |
| Kalispell Regional Medical Center | Kalispell | Montana | 59901 | Recruiting |
| Community Medical Center | Missoula | Montana | 59804 | Recruiting |
| Nebraska Medicine-Bellevue | Bellevue | Nebraska | 68123 | Recruiting |
| Nebraska Medicine-Village Pointe | Omaha | Nebraska | 68118 | Recruiting |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | Recruiting |
| Indu and Raj Soin Medical Center | Beavercreek | Ohio | 45431 | Recruiting |
| Saint Elizabeth Boardman Hospital | Boardman | Ohio | 44512 | Recruiting |
| Dayton Physicians LLC-Miami Valley South | Centerville | Ohio | 45459 | Recruiting |
| Oncology Hematology Care Inc-Kenwood | Cincinnati | Ohio | 45236 | Recruiting |
| Dayton Physician LLC - Englewood | Dayton | Ohio | 45415 | Recruiting |
| Armes Family Cancer Center | Findlay | Ohio | 45840 | Recruiting |
| Blanchard Valley Hospital | Findlay | Ohio | 45840 | Recruiting |
| Orion Cancer Care | Findlay | Ohio | 45840 | Recruiting |
| Dayton Physicians LLC-Atrium | Franklin | Ohio | 45005 | Recruiting |
| Dayton Physicians LLC-Wayne | Greenville | Ohio | 45331 | Recruiting |
| Wayne Hospital | Greenville | Ohio | 45331 | Recruiting |
| Greater Dayton Cancer Center | Kettering | Ohio | 45409 | Recruiting |
| Kettering Medical Center | Kettering | Ohio | 45429 | Recruiting |
| Dayton Physicians LLC - Troy | Troy | Ohio | 45373 | Recruiting |
| Saint Joseph Warren Hospital | Warren | Ohio | 44484 | Recruiting |
| Saint Elizabeth Youngstown Hospital | Youngstown | Ohio | 44501 | Recruiting |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | Recruiting |
| Saint Alphonsus Cancer Care Center-Baker City | Baker City | Oregon | 97814 | Recruiting |
| Saint Alphonsus Cancer Care Center-Ontario | Ontario | Oregon | 97914 | Recruiting |
| Lehigh Valley Hospital-Cedar Crest | Allentown | Pennsylvania | 18103 | Recruiting |
| Lehigh Valley Hospital - Muhlenberg | Bethlehem | Pennsylvania | 18017 | Recruiting |
| Christiana Care Health System-Concord Health Center | Chadds Ford | Pennsylvania | 19317 | Recruiting |
| Pocono Medical Center | East Stroudsburg | Pennsylvania | 18301 | Recruiting |
| Lehigh Valley Hospital-Hazleton | Hazleton | Pennsylvania | 18201 | Recruiting |
| The West Clinic - Wolf River | Germantown | Tennessee | 38138 | Recruiting |
| MD Anderson in The Woodlands | Conroe | Texas | 77384 | Recruiting |
| Lyndon Baines Johnson General Hospital | Houston | Texas | 77026-1967 | Recruiting |
| M D Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| MD Anderson West Houston | Houston | Texas | 77079 | Recruiting |
| MD Anderson League City | League City | Texas | 77573 | Recruiting |
| MD Anderson in Sugar Land | Sugar Land | Texas | 77478 | Recruiting |
| VCU Massey Cancer Center at Stony Point | Richmond | Virginia | 23235 | Recruiting |
| Virginia Commonwealth University/Massey Cancer Center | Richmond | Virginia | 23298 | Recruiting |
| Cancer Center of Western Wisconsin | New Richmond | Wisconsin | 54017 | Recruiting |
| Billings Clinic-Cody | Cody | Wyoming | 82414 | Recruiting |
| Welch Cancer Center | Sheridan | Wyoming | 82801 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06470243, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 21, 2026 · Synced May 9, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06470243 live on ClinicalTrials.gov.