A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease
Public ClinicalTrials.gov record NCT06481306. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2a, First-in-human, Randomized, Double-blinded, Placebo-controlled, Dose-finding Study in Healthy Volunteers and Participants With Sickle Cell Disease to Evaluate the Safety and Tolerability, Pharmacokinetics, Pharmacodynamics, pH and Food Effect, and Preliminary Efficacy of BMS-986470
Study identification
- NCT ID
- NCT06481306
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Bristol-Myers Squibb
- Industry
- Enrollment
- 184 participants
Conditions and interventions
Conditions
Interventions
- BMS-986470 Drug
- Placebo Drug
- Famotidine Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 16, 2024
- Primary completion
- Jan 5, 2027
- Completion
- Nov 15, 2027
- Last update posted
- Jun 15, 2026
2024 – 2027
United States locations
- U.S. sites
- 20
- U.S. states
- 15
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | Recruiting |
| University of California San Diego - La Jolla | La Jolla | California | 92037 | Recruiting |
| UCSF Benioff Children's Hospital Oakland | Oakland | California | 94609 | Recruiting |
| Yale-New Haven Hospital | New Haven | Connecticut | 06510 | Recruiting |
| Local Institution - 0035 | Tampa | Florida | 33607 | Not yet recruiting |
| Winship Cancer Institute of Emory University | Atlanta | Georgia | 30322 | Recruiting |
| Local Institution - 0034 | Chicago | Illinois | 60612 | Not yet recruiting |
| Local Institution - 0001 | Lenexa | Kansas | 66219 | Active, not recruiting |
| Local Institution - 0064 | Baltimore | Maryland | 21287 | Not yet recruiting |
| Local Institution - 0024 | Boston | Massachusetts | 02114 | Not yet recruiting |
| Boston Medical Center | Boston | Massachusetts | 02118 | Recruiting |
| Local Institution - 0030 | St Louis | Missouri | 63110 | Not yet recruiting |
| Local Institution - 0033 | Greenville | North Carolina | 27834 | Not yet recruiting |
| Local Institution - 0028 | Cleveland | Ohio | 44195 | Not yet recruiting |
| Local Institution - 0029 | Philadelphia | Pennsylvania | 19104 | Not yet recruiting |
| Thomas Jefferson University - Medicine/GI and Hepatology | Philadelphia | Pennsylvania | 19107 | Recruiting |
| Local Institution - 0032 | Pittsburgh | Pennsylvania | 15213 | Not yet recruiting |
| Local Institution - 0027 | Greenville | South Carolina | 29605 | Not yet recruiting |
| Inova Schar Cancer Institute | Fairfax | Virginia | 22031 | Recruiting |
| Virginia Commonwealth University (VCU) Medical Center | Richmond | Virginia | 23298 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06481306, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 15, 2026 · Synced Jun 25, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06481306 live on ClinicalTrials.gov.