ClinicalTrials.gov record
Open-label Extension Study of Enlicitide Decanoate (MK-0616/Enlicitide Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-019) CORALreef Extension
ClinicalTrials.gov ID: NCT06492291
Public ClinicalTrials.gov record NCT06492291. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Open-label Extension Study to Evaluate the Safety and Efficacy of MK-0616 in Adults With Hypercholesterolemia
Study identification
- NCT ID
- NCT06492291
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Merck Sharp & Dohme LLC
- Industry
- Enrollment
- 3,000 participants
Conditions and interventions
Conditions
Interventions
- Enlicitide Decanoate Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 4, 2024
- Primary completion
- Oct 12, 2028
- Completion
- Oct 12, 2028
- Last update posted
- Oct 6, 2025
2024 – 2028
United States locations
- U.S. sites
- 52
- U.S. states
- 27
- U.S. cities
- 51
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alliance for Multispecialty Research, LLC ( Site 0027) | Daphne | Alabama | 36526 | — |
| G&L Research ( Site 0035) | Foley | Alabama | 36535 | — |
| Synexus Clinical Research US, Inc.-Synexus Clinical Research US, Inc - Central Phoenix ( Site 0048) | Phoenix | Arizona | 85020 | — |
| National Heart Institute-Research ( Site 0029) | Beverly Hills | California | 90211 | — |
| Clinical Trials Research ( Site 0054) | Sacramento | California | 95821 | — |
| Velocity Clinical Research, Banning ( Site 0023) | San Bernardino | California | 92408 | — |
| Emerson Clinical Research Institute ( Site 0017) | Washington D.C. | District of Columbia | 20009 | — |
| Excel Medical Clinical Trials ( Site 0010) | Boca Raton | Florida | 33434 | — |
| Alliance for Multispecialty Research, LLC ( Site 0037) | Doral | Florida | 33172 | — |
| Alliance for Multispecialty Research, LLC ( Site 0056) | Fort Myers | Florida | 33912 | — |
| Velocity Clinical Research, Hallandale Beach ( Site 0053) | Hallandale | Florida | 33009 | — |
| Jacksonville Center for Clinical Research ( Site 0025) | Jacksonville | Florida | 32216 | — |
| South Broward Research ( Site 0012) | Miramar | Florida | 33027 | — |
| Progressive Medical Research ( Site 0033) | Port Orange | Florida | 32127 | — |
| Clinical Research Trials of Florida ( Site 0006) | Tampa | Florida | 33607 | — |
| Clinical Site Partners, LLC dba Flourish Research ( Site 0004) | Winter Park | Florida | 32789 | — |
| East Coast Institute for Research, LLC ( Site 0020) | Macon | Georgia | 31210 | — |
| Healthcare Research Network - Chicago ( Site 0051) | Flossmoor | Illinois | 60422 | — |
| Synexus Clinical Research US - Evansville ( Site 0005) | Evansville | Indiana | 47714 | — |
| Midwest Institute For Clinical Research ( Site 0052) | Indianapolis | Indiana | 46260 | — |
| Alliance for Multispecialty Research, LLC ( Site 0001) | Lexington | Kentucky | 40509 | — |
| L-MARC Research Center ( Site 0011) | Louisville | Kentucky | 40213 | — |
| Velocity Clinical Research, Covington ( Site 0026) | Covington | Louisiana | 70433 | — |
| Velocity Clinical Research Rockville ( Site 0022) | Rockville | Maryland | 20854 | — |
| Arcturus Healthcare , PLC, Troy Internal Medicine Research Division ( Site 0018) | Troy | Michigan | 48098 | — |
| Velocity Clinical Research, Gulfport ( Site 0032) | Gulfport | Mississippi | 39503 | — |
| Healthcare Research Network - St. Louis ( Site 0040) | Hazelwood | Missouri | 63042 | — |
| Velocity Clinical Research at The Pioneer Heart Institute, Lincoln ( Site 0031) | Lincoln | Nebraska | 68510 | — |
| Jubilee Clinical Research ( Site 0049) | Las Vegas | Nevada | 89106 | — |
| AB Clinical Trials ( Site 0002) | Las Vegas | Nevada | 89119 | — |
| New Mexico Clinical Research & Osteoporosis Center ( Site 0043) | Albuquerque | New Mexico | 87106 | — |
| Velocity Clinical Research, Syracuse ( Site 0014) | East Syracuse | New York | 13057 | — |
| Icahn School of Medicine at Mount Sinai-Cardiology ( Site 0042) | New York | New York | 10029 | — |
| Lillestol Research ( Site 0030) | Fargo | North Dakota | 58104 | — |
| altoona center for clinical research ( Site 0024) | Duncansville | Pennsylvania | 16635 | — |
| Cardiology Consultants of Philadelphia Yardley ( Site 0021) | Yardley | Pennsylvania | 19067 | — |
| Velocity Clinical Research, Anderson ( Site 0015) | Anderson | South Carolina | 29621 | — |
| Piedmont Research Partners ( Site 0045) | Fort Mill | South Carolina | 29707 | — |
| Coastal Carolina Research Center ( Site 0055) | North Charleston | South Carolina | 29405 | — |
| Monument Health Clinical Research, a department of Monument -Monument Health Clinical Research, a d ( Site 0038) | Rapid City | South Dakota | 57701 | — |
| Holston Medical Group ( Site 0034) | Kingsport | Tennessee | 37660 | — |
| Alliance for Multispecialty Research, LLC ( Site 0050) | Knoxville | Tennessee | 37920 | — |
| Velocity Clinical Research, Dallas ( Site 0028) | Dallas | Texas | 75230 | — |
| Center for Cardiometabolic Disease Prevention/Baylor College of Medicine ( Site 0009) | Houston | Texas | 77030 | — |
| Clinical Trials of Texas, LLC ( Site 0016) | San Antonio | Texas | 78229 | — |
| Synexus Clinical Research US, Inc. ( Site 0003) | Salt Lake City | Utah | 84106 | — |
| Velocity Clinical Research, Salt Lake City ( Site 0041) | West Jordan | Utah | 84088 | — |
| Manassas Clinical Research Center ( Site 0007) | Manassas | Virginia | 20110 | — |
| Health Research of Hampton Roads, Inc. ( Site 0019) | Newport News | Virginia | 23606 | — |
| Alliance for Multispecialty Research, LLC ( Site 0008) | Norfolk | Virginia | 23502 | — |
| National Clinical Research, Inc ( Site 0044) | Richmond | Virginia | 23294 | — |
| Rainier Clinical Research Center ( Site 0013) | Renton | Washington | 98057 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 170 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06492291, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 6, 2025 · Synced Jul 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06492291 live on ClinicalTrials.gov.