Study to Assess the Efficacy, Safety, and Tolerability of NOC-110 in Adults With Refractory or Unexplained Chronic Cough
Public ClinicalTrials.gov record NCT06504446. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of Taplucainium Inhalation Powder (NOC-110) in Adults With Refractory or Unexplained Chronic Cough
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a phase 2b, randomized, double-blind, placebo-controlled study investigating the efficacy, safety, and tolerability of Taplucainium Inhalation Powder (NOC-110) once daily in adults with refractory or unexplained chronic cough.
Study identification
- NCT ID
- NCT06504446
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 455 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 24, 2024 (Actual)
- Primary completion
- Jun 15, 2026 (Estimated)
- Completion
- Jun 29, 2026 (Estimated)
- Last update posted
- Jun 11, 2026
2024 – 2026
United States locations
- U.S. sites
- 68
- U.S. states
- 30
- U.S. cities
- 63
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| G & L Research, LLC | Foley | Alabama | 36535 | — |
| Medical Research of Arizona | Scottsdale | Arizona | 85251 | — |
| AMR Phoenix | Tempe | Arizona | 85281 | — |
| Little Rock Allergy & Asthma, P.A. Clinical Research Center | Little Rock | Arkansas | 72205 | — |
| So Cal Clinical Research | Huntington Beach | California | 92647 | — |
| Allergy and Asthma Associates of Southern California dba Southern California Research | Laguna Niguel | California | 92677 | — |
| Paradigm Clinical Research Centers, LLC - Modesto | Modesto | California | 95355 | — |
| NewportNativeMD,Inc | Newport Beach | California | 92663 | — |
| Center for Clinical Trials, LLC | Paramount | California | 90723 | — |
| Paradigm Clinical Research Centers, LLC | Redding | California | 96001 | — |
| DaVinci Research LLC. | Roseville | California | 95661 | — |
| Allergy & Asthma Associates of Santa Clara Valley | San Jose | California | 95117 | — |
| California Allergy & Asthma Medical Group Inc. | San Jose | California | 95117 | — |
| Allergy, Asthma, and Immunology Medical Group | Ventura | California | 93003 | — |
| Allergy and Asthma Clinical Research Inc | Walnut Creek | California | 94598 | — |
| Lynn Institute of Denver | Aurora | Colorado | 80012 | — |
| Innovative Research of West Florida, Inc. | Clearwater | Florida | 33756 | — |
| Omega Research Debary, LLC | DeBary | Florida | 32713 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| Clinical Site Partners, LLC Leesburg dba Flourish Research | Leesburg | Florida | 34748 | — |
| Suncoast Research Group, LLC Miami - Little Havana dba Flourish Research | Miami | Florida | 33135 | — |
| Well Pharma Medical Research Corporation | Miami | Florida | 33173 | — |
| University of South Florida - PARENT | Tampa | Florida | 33613 | — |
| Clinical Site Partners, LLC Orlando dba Flourish Research | Winter Park | Florida | 32789 | — |
| Aeroallergy Research Laboratories of Savannah, Inc. | Savannah | Georgia | 31406 | — |
| Duly Health and Care | Winfield | Illinois | 60190 | — |
| Accellacare of McFarland Clinic | Ames | Iowa | 50010 | — |
| The Iowa Clinic, PC | West Des Moines | Iowa | 50266 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Bluegrass Allergy Research | Lexington | Kentucky | 40509 | — |
| Allergy & Asthma Specialists, PSC | Owensboro | Kentucky | 42301 | — |
| Continental Clinical Solutions, LLC | Towson | Maryland | 21204 | — |
| Infinity Medical Research Inc | Russells Mills | Massachusetts | 02747 | — |
| Clinical Research Institute | Minneapolis | Minnesota | 55402 | — |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55905 | — |
| The Curators of the University of Missouri on behalf of University of Missouri Health Care | Columbia | Missouri | 65212 | — |
| Midwest Chest Consultants | Saint Charles | Missouri | 63301 | — |
| Sundance Clinical Research | St Louis | Missouri | 63141 | — |
| The Clinical Research Center, LLC | St Louis | Missouri | 63141 | — |
| Montana Medical Research, Inc. | Missoula | Montana | 59808 | — |
| AMR Las Vegas | Las Vegas | Nevada | 89119 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Allergy Partners of New Jersey P C | Ocean City | New Jersey | 07712 | — |
| The Valley Hospital | Paramus | New Jersey | 07652 | — |
| St Josephs Physicians Med PC Pulmonary Health | Liverpool | New York | 13088 | — |
| Equity Medical LLC | New York | New York | 10023 | — |
| Allergy Partners Clinical Research | Asheville | North Carolina | 28803 | — |
| Clinical Research of Gastonia | Gastonia | North Carolina | 28054 | — |
| M3 Wake Research, Inc. | Raleigh | North Carolina | 27612 | — |
| Accellacare | Winston-Salem | North Carolina | 27103 | — |
| Southeastern Research Center LLC | Winston-Salem | North Carolina | 27103 | — |
| Remington-Davis, Inc. | Columbus | Ohio | 43215 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| Vital Prospects Clinical Research Institute, P.C. | Tulsa | Oklahoma | 74136 | — |
| Northwest Research Center | Portland | Oregon | 97202 | — |
| Suburban Research Associates | West Chester | Pennsylvania | 19380 | — |
| Care Access Research - Warwick 1 | Warwick | Rhode Island | 02886 | — |
| Lowcountry Lung and Critical Care, P.A. | Charleston | South Carolina | 29406 | — |
| Accellacare | Mt. Pleasant | South Carolina | 29464 | — |
| Clinical Research of Rock Hill | Rock Hill | South Carolina | 29732 | — |
| Internal Medicine and Pediatric Associates of Bristol, PC | Bristol | Tennessee | 37620 | — |
| Accellacare d/b/a Accellacare of Knoxville | Knoxville | Tennessee | 37938 | — |
| Pharmaceutical Research & Consulting, Inc. | Dallas | Texas | 75231 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| South Texas Allergy & Asthma Medical Professionals | San Antonio | Texas | 78229 | — |
| Alamo ENT Associates | San Antonio | Texas | 78258 | — |
| TPMG Clinical Research Williamsburg | Williamsburg | Virginia | 23188 | — |
| Allergy, Asthma & Sinus Center, SC | Greenfield | Wisconsin | 53228 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 38 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06504446, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 11, 2026 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06504446 live on ClinicalTrials.gov.