Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

ClinicalTrials.gov ID: NCT06538038

Public ClinicalTrials.gov record NCT06538038. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 6, 2026, 8:51 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Prospective Non-Interventional Study Comparing Standard of Care Osimertinib +/- Chemotherapy for EGFR-Mutated Non-Small Cell Lung Cancer (NSCLC) Patients

Study identification

NCT ID: NCT06538038
Recruitment status: Recruiting
Study type: Observational
Phase: Not listed
Lead sponsor: PrECOG, LLC.; Other
Enrollment: 538 participants

Conditions and interventions

Conditions

Interventions

Osimertinib Drug
Osimertinib + Chemotherapy Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Sep 16, 2024
Primary completion: Jul 31, 2028
Completion: Jul 31, 2029
Last update posted: Mar 26, 2026

2024 – 2029

United States locations

U.S. sites: 146
U.S. states: 22
U.S. cities: 124

Facility	City	State	ZIP	Site status
University of Alabama at Birmingham	Birmingham	Alabama	35294	Recruiting
Mercy Clinic Fort Smith Communities	Fort Smith	Arkansas	72903	Recruiting
Mercy Research	Fort Smith	Arkansas	72903	Recruiting
Fowler Family Cancer Center - Jonesboro	Jonesboro	Arkansas	72401	Recruiting
Stanford Cancer Center Emeryville	Emeryville	California	94608	Recruiting
Stanford Cancer Institute Palo Alto	Palo Alto	California	94304	Recruiting
Stanford Cancer Center South Bay	San Jose	California	95124	Recruiting
John Muir Health	Walnut Creek	California	94598	Recruiting
Bayhealth	Dover	Delaware	19901	Recruiting
Satellite of Bayhealth Sussex	Milford	Delaware	19901	Recruiting
Sibley Johns Hopkins University	Washington D.C.	District of Columbia	20016	Recruiting
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler: Liberty County Cancer Care	Hinesville	Georgia	31313	Recruiting
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler: Regional Cancer Care	Jesup	Georgia	31545	Recruiting
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler	Savannah	Georgia	31405	Recruiting
Advocate Good Shepherd Hospital	Barrington	Illinois	60010	Recruiting
Northwestern University	Chicago	Illinois	60611	Recruiting
John H Stroger Jr Hospital of Cook County	Chicago	Illinois	60612	Recruiting
Advocate Illinois Masonic Medical Center	Chicago	Illinois	60657	Recruiting
Northwestern Medicine Cancer Center Kishwaukee	DeKalb	Illinois	60115	Recruiting
Northwestern Medicine Cancer Center Delnor	Geneva	Illinois	60134	Recruiting
Northwestern Medicine Glenview Outpatient Center	Glenview	Illinois	60026	Recruiting
Northwestern Medicine Grayslake Outpatient Center	Grayslake	Illinois	60030	Recruiting
Advocate South Suburban Hospital	Hazel Crest	Illinois	60429	Recruiting
Northwestern Medicine Lake Forest Hospital	Lake Forest	Illinois	60045	Recruiting
Carle Cancer Institute Normal	Normal	Illinois	61761	Recruiting
Advocate Christ Medical Center	Oak Lawn	Illinois	60453	Recruiting
Northwestern Medicine Orland Park	Orland Park	Illinois	60462	Recruiting
Advocate Lutheran General Hospital	Park Ridge	Illinois	60068	Recruiting
Carle Founation Hospital	Urbana	Illinois	61801	Recruiting
Northwestern Medicine Cancer Center Warrenville	Warrenville	Illinois	60555	Recruiting
University of Maryland Greenebaum Comprehensive Cancer Center	Baltimore	Maryland	21201	Recruiting
Greater Baltimore Medical Center	Baltimore	Maryland	21204	Recruiting
Tufts Medical Center	Boston	Massachusetts	02111	Recruiting
Lowell General Hosptial	Lowell	Massachusetts	01854	Recruiting
Tufts Medical Center Cancer Center Stoneham	Stoneham	Massachusetts	02180	Recruiting
Minnesota Oncology - Burnsville	Burnsville	Minnesota	55337	Recruiting
Cambridge Medical Center	Cambridge	Minnesota	55008	Recruiting
Mercy Hospital	Coon Rapids	Minnesota	55433	Recruiting
Fairview Southdale Hospital	Edina	Minnesota	55435	Recruiting
Fairview Clinics and Surgery Center Maple Grove	Maple Grove	Minnesota	55369	Recruiting
Minnesota Oncology Hematology PA-Maplewood	Maplewood	Minnesota	55109	Recruiting
Saint John's Hospital - Healtheast	Maplewood	Minnesota	55109	Recruiting
Abbott-Northwestern Hospital	Minneapolis	Minnesota	55407	Recruiting
Hennepin County Medical Center	Minneapolis	Minnesota	55415	Recruiting
Health Partners Inc.	Minneapolis	Minnesota	55454	Recruiting
Monticello Cancer Center	Monticello	Minnesota	55362	Recruiting
New Ulm Medical Center	New Ulm	Minnesota	56073	Recruiting
Fairview Northland Medical Center	Princeton	Minnesota	55371	Recruiting
North Memorial Medical Health Center	Robbinsdale	Minnesota	55422	Recruiting
Park Nicollet Clinic - Saint Louis Park	Saint Louis Park	Minnesota	55416	Recruiting
Metro MN	Saint Louis Park	Minnesota	55426	Recruiting
Regions Hospital	Saint Paul	Minnesota	55101	Recruiting
United Hospital	Saint Paul	Minnesota	55102	Recruiting
Saint Francis Regional Medical Center	Shakopee	Minnesota	55379	Recruiting
Lakeview Hospital	Stillwater	Minnesota	55082	Recruiting
Ridgeview Medical Center	Waconia	Minnesota	55387	Recruiting
Rice Memorial Hospital	Willmar	Minnesota	56201	Recruiting
Minnesota Oncology Hematology PA-Woodbury	Woodbury	Minnesota	55125	Recruiting
Fairview Lakes Medical Center	Wyoming	Minnesota	55092	Recruiting
Baptist Memorial Hospital and Cancer Center - Golden Triangle	Columbus	Mississippi	39705	Recruiting
Baptist Cancer Center - Grenada	Grenada	Mississippi	38901	Recruiting
Jackson Oncology Associates PLLC	Jackson	Mississippi	39202	Recruiting
Mississippi Baptist Medical Center	Jackson	Mississippi	39202	Recruiting
Baptist Memorial Hospital and Cancer Center - Union	New Albany	Mississippi	38652	Recruiting
Baptist Memorial Hospital and Cancer Center - Oxford	Oxford	Mississippi	38655	Recruiting
Baptist Memorial Hospital and Cancer Center - Desoto	Southhaven	Mississippi	38671	Recruiting
Mercy Clinic Joplin, LLC	Joplin	Missouri	64804	Recruiting
Mercy Clinic Cancer and Hematology	Rolla	Missouri	65401	Recruiting
Mercy Clinic Springfield Communities	Springfield	Missouri	65804	Recruiting
Mercy Clinic East Communities	St Louis	Missouri	63128	Recruiting
Mercy Clinic East Communities	St Louis	Missouri	63141	Recruiting
Virtua Samson Cancer Center	Moorestown	New Jersey	08057	Recruiting
Atlantic Health Cancer Consortium Community Oncology Research Program	Morristown	New Jersey	07960	Recruiting
Morristown Medical Center	Morristown	New Jersey	07960	Recruiting
Rutgers Cancer Institute of New Jersey	New Brunswick	New Jersey	08903	Recruiting
The Valley Hospital - Luckow Pavilion	Paramus	New Jersey	07652	Recruiting
Sidney Kimmel Cancer Center Washington Township	Sewell	New Jersey	08080	Recruiting
Overlook Medical Center	Summit	New Jersey	07901	Recruiting
Virtua Voorhees	Voorhees Township	New Jersey	08043	Recruiting
The Cancer Institute at St. Francis Hospital	East Hills	New York	11548	Recruiting
Montefiore	New York	New York	10467	Recruiting
SUNY Upstate Medical University	Syracuse	New York	13210	Recruiting
Montefiore Medical Center-Einstein Campus	The Bronx	New York	10461	Recruiting
Good Samaritan University Hospital	West Islip	New York	11795	Recruiting
UNC Pardee Cancer Center	Hendersonville	North Carolina	28791	Recruiting
FirstHealth of the Carolinas-Moore Regional Hospital	Pinehurst	North Carolina	28374	Recruiting
Aultman	Canton	Ohio	44710	Recruiting
Miami Valley Hospital South	Centerville	Ohio	45459	Recruiting
Miami Valley Hospital North	Englewood	Ohio	45415	Recruiting
Atrium Medical Center-Middletown Regional Hospital	Franklin	Ohio	45005	Recruiting
Miami Valley Cancer Care and Infusion	Greenville	Ohio	45331	Recruiting
Upper Valley Medical Center	Troy	Ohio	45373	Recruiting
Mercy Clinic Oklahoma Communities, Inc.	Oklahoma City	Oklahoma	73120	Recruiting
Geisinger Medical Center	Danville	Pennsylvania	17822	Recruiting
Geisinger Medical Center-Cancer Center Hazleton	Hazleton	Pennsylvania	18201	Recruiting
Geisinger Medical Oncology-Lewisburg	Lewisburg	Pennsylvania	17837	Recruiting
Lewistown Hospital	Lewistown	Pennsylvania	17044	Recruiting
Lankenau Medical Center	Paoli	Pennsylvania	19301	Recruiting
University of Pennsylvania	Philadelphia	Pennsylvania	19104	Recruiting
Thomas Jefferson University Hospital	Philadelphia	Pennsylvania	19107	Recruiting
Jefferson Torresdale Hospital	Philadelphia	Pennsylvania	19114	Recruiting
Einstein Medical Center	Philadelphia	Pennsylvania	19141	Recruiting
Allegheny General Hospital	Pittsburgh	Pennsylvania	15212	Recruiting
Geisinger Cancer Services-Pottsville	Pottsville	Pennsylvania	17901	Recruiting
Community Medical Center	Scranton	Pennsylvania	18510	Recruiting
Geisinger Medical Group	State College	Pennsylvania	16801	Recruiting
Geisinger Wyoming Valley/Henry Cancer Center	Wilkes-Barre	Pennsylvania	18711	Recruiting
Asplundh Cancer Pavilion	Willow Grove	Pennsylvania	19090	Recruiting
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler: SJC Bluffton Campus	Bluffton	South Carolina	29910	Recruiting
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler: South Carolina Cancer Specialists	Hilton Head Island	South Carolina	29926	Recruiting
Baptist Memorial Hospital and Cancer Center - Collierville	Collierville	Tennessee	38017	Recruiting
Baptist Memorial Hospital and Cancer Center - Memphis	Memphis	Tennessee	38120	Recruiting
Baptist Memorial Hospital for Women	Memphis	Tennessee	38120	Recruiting
Vanderbilt University	Nashville	Tennessee	37232	Recruiting
UT Southwest	Dallas	Texas	75235	Recruiting
JPS Oncology & Infusion Center	Fort Worth	Texas	76104	Recruiting
ThedaCare Regional Cancer Center	Appleton	Wisconsin	54911	Recruiting
ThedaCare Regional Medical Center - Appleton	Appleton	Wisconsin	54911	Recruiting
ThedaCare Cancer Care - Berlin	Berlin	Wisconsin	54923	Recruiting
Aurora Cancer Care-Southern Lakes VLCC	Burlington	Wisconsin	53105	Recruiting
Aurora Saint Luke's South Shore	Cudahy	Wisconsin	53110	Recruiting
AHC Germantown Health Center	Germantown	Wisconsin	53022	Recruiting
Aurora Cancer Care-Grafton	Grafton	Wisconsin	53024	Recruiting
Aurora BayCare Medical Center	Green Bay	Wisconsin	54311	Recruiting
Mercyhealth Hospital and Cancer Center - Janesville	Janesville	Wisconsin	53548	Recruiting
Aurora Cancer Care-Kenosha South	Kenosha	Wisconsin	53142	Recruiting
Gundersen Lutheran Medical Foundation	La Crosse	Wisconsin	54601	Recruiting
University of Wisconsin Carbone Cancer Center	Madison	Wisconsin	53715	Recruiting
Marshfield Medical Center	Marshfield	Wisconsin	54449	Recruiting
Aurora Cancer Care-Milwaukee	Milwaukee	Wisconsin	53209	Recruiting
Aurora NCORP	Milwaukee	Wisconsin	53215	Recruiting
Aurora Saint Luke's Medical Center	Milwaukee	Wisconsin	53215	Recruiting
Aurora West Allis Medical Center	Milwaukee	Wisconsin	53227	Recruiting
Aurora Sinai Medical Center	Milwaukee	Wisconsin	53233	Recruiting
ThedaCare Regional Medical Center - Neenah	Neenah	Wisconsin	54956	Recruiting
ThedaCare Cancer Care - New London	New London	Wisconsin	54961	Recruiting
ThedaCare Cancer Care - Oshkosh	Oshkosh	Wisconsin	54904	Recruiting
Vince Lombardi Cancer Clinic-Oshkosh	Oshkosh	Wisconsin	54904	Recruiting
Aurora Cancer Care-Racine	Racine	Wisconsin	53406	Recruiting
ThedaCare Cancer Care - Shawano	Shawano	Wisconsin	54166	Recruiting
Vince Lombardi Cancer Clinic-Sheboygan	Sheboygan	Wisconsin	53081	Recruiting
Aurora Medical Center in Summit	Summit	Wisconsin	53066	Recruiting
Vince Lombardi Cancer Clinic-Two Rivers	Two Rivers	Wisconsin	54241	Recruiting
ProHealth	Waukesha	Wisconsin	53022	Recruiting
ThedaCare Cancer Care - Waupaca	Waupaca	Wisconsin	54981	Recruiting
Aurora Cancer Care-Milwaukee West	Wauwatosa	Wisconsin	53226	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06538038, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Mar 26, 2026 · Synced May 6, 2026

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The complete protocol, eligibility criteria, and contact information for NCT06538038 live on ClinicalTrials.gov.

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