A Study to Compare Nighttime Aligners to Daytime Aligners
Public ClinicalTrials.gov record NCT06539676. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Prospective, Two-armed, Multicenter Clinical Study to Evaluate Efficacy, Performance, and Safety of Nighttime Aligners (Worn 10-12 Hours Day or Night) Compared to Daytime Aligners (Worn 20-22 Hours Day/Night)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this research study is to see if Nighttime Aligners (worn 10-12 hours per day or night) are effective and safe for tooth movement and if so, how they compare with the standard Daytime aligners (worn 20-22 hours per day), in adults and children from 12 years of age and older. It will investigate the efficacy and performance of the treatments, as well as the safety of the investigational device and comparator. The main objectives are: * Comparison between the two groups concerning actual vs planned tooth movements (measured by changes in tooth position) * Comparison between the two groups concerning the incidence of device or dental related AEs. * Overall dentist and participant satisfaction with the treatment. Participants will: * Be given orthodontic aligner therapy with the Daytime (20-22h/day) or Nighttime (10-12h/day) Aligners (randomly assigned) * Attend approximately 5 study during approximately 8-10 months
Study identification
- NCT ID
- NCT06539676
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 7 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 3, 2024
- Primary completion
- Jan 16, 2025
- Completion
- Jan 16, 2025
- Last update posted
- Jul 15, 2025
2024 – 2025
United States locations
- U.S. sites
- 12
- U.S. states
- 10
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Fulbright Dental | Redondo Beach | California | 90277 | — |
| 3D Dental | Miami Beach | Florida | 33140 | — |
| Elite Dental of Towson | Towson | Maryland | 21204 | — |
| Cedars Family Dental | Plainville | Massachusetts | 02762 | — |
| R. Lobato & Associates | Las Vegas | Nevada | 89117 | — |
| Aesthetic Dental | North Bergen | New Jersey | 07047 | — |
| Huerta Dentistry | New York | New York | 10001 | — |
| Brush365 | Frisco | Texas | 75035 | — |
| Gustafson Dental | Humble | Texas | 77396 | — |
| SKM Dentistry d/b/a brush365 Dental | Hurst | Texas | 76003 | — |
| Northwest Dental Medicine | Puyallup | Washington | 98372 | — |
| Gregson Family Dentistry | Milwaukee | Wisconsin | 17655 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06539676, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 15, 2025 · Synced Sep 3, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06539676 live on ClinicalTrials.gov.