Evaluate Efficacy and Safety of POS to Improve Distance-corrected Near Visual in Participants With Presbyopia
Public ClinicalTrials.gov record NCT06542497. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized, Double-masked, Placebo-controlled, Multicenter Study of the Efficacy and Safety of Phentolamine Ophthalmic Solution (POS) 0.75% in Participants With Presbyopia
Study identification
- NCT ID
- NCT06542497
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Ocuphire Pharma, Inc.
- Industry
- Enrollment
- 569 participants
Conditions and interventions
Conditions
Interventions
- 0.75% phentolamine ophthalmic solution Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 45 Years to 64 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 14, 2024
- Primary completion
- Apr 2, 2025
- Completion
- Jan 21, 2026
- Last update posted
- Mar 11, 2026
2024 – 2026
United States locations
- U.S. sites
- 39
- U.S. states
- 17
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Eye Center | Chandler | Arizona | 85224 | — |
| Carrot Eye Center | Mesa | Arizona | 85202 | — |
| Eye Doctors of Arizona | Phoenix | Arizona | 85028 | — |
| MRB Eye Care Consultants, LLC | Scottsdale | Arizona | 85260 | — |
| Empire Eye & Laser Center | Bakersfield | California | 93309 | — |
| Global Research Management, Inc. | Glendale | California | 91204 | — |
| Gordon Schanzlin New Vision Institute | La Jolla | California | 92307 | — |
| LoBue Laser and Eye Medical Center, Inc. | Murrieta | California | 92562 | — |
| Eye Research Foundation | Newport Beach | California | 92663 | — |
| Wolstan and Goldberg Eye Associates | Torrance | California | 90505 | — |
| Segal Drug Trials, Inc. | Delray Beach | Florida | 33484 | — |
| South Florida Glaucoma | Delray Beach | Florida | 33484 | — |
| Levenson Eye | Jacksonville | Florida | 32204 | — |
| Bowden Eye & Associates | Jacksonville | Florida | 32256 | — |
| Shettle Eye Research | Largo | Florida | 33773 | — |
| Sabal Eye Care/dba Omega Vision Center | Longwood | Florida | 32779 | — |
| Mid Florida Eye Center | Mt. Dora | Florida | 32757 | — |
| Virdi Eye Clinic | Rock Island | Illinois | 61201 | — |
| Price Vision Group | Indianapolis | Indiana | 46260 | — |
| Durrie Vision | Overland Park | Kansas | 66210 | — |
| Kannarr Eye Care | Pittsburg | Kansas | 66762 | — |
| Heart of America Eye Care, P.A. | Shawnee Mission | Kansas | 66204 | — |
| The Eye Care Institute | Louisville | Kentucky | 40206 | — |
| Fraser Eye Care Center | Fraser | Michigan | 48026 | — |
| Moyes Eye Center | Kansas City | Missouri | 64154 | — |
| Rochester Ophthalmological Group | Rochester | New York | 14618 | — |
| Oculus Research , Inc. | Garner | North Carolina | 27529 | — |
| Bergstrom Eye | Fargo | North Dakota | 58103 | — |
| Red River Research Partners | Fargo | North Dakota | 58103 | — |
| Athens Eye Care | Athens | Ohio | 45701 | — |
| West Bay Eye Associates | Warwick | Rhode Island | 02888 | — |
| Advancing Vision Research | Goodlettsville | Tennessee | 37072 | — |
| Optometry Group | Memphis | Tennessee | 38111 | — |
| Total Eye Care | Memphis | Tennessee | 38119 | — |
| Whitsett Vision Group | Houston | Texas | 77055 | — |
| Lake Travis Eye and Laser Center/ Revolution Research | Lakeway | Texas | 78738 | — |
| Red River Research Partners | Richardson | Texas | 75080 | — |
| Parkhurst NuVision | San Antonio | Texas | 78229 | — |
| Eye Institute of Utah | Salt Lake City | Utah | 84107 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06542497, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 11, 2026 · Synced Jun 25, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06542497 live on ClinicalTrials.gov.