A Research Study Comparing How Well Different Doses of the Medicine NNC0487-0111 Lower Blood Sugar in People With Type 2 Diabetes
Public ClinicalTrials.gov record NCT06542874. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Safety and Efficacy of Once-weekly Subcutaneous and Once-daily Oral NNC0487-0111 in Participants With Type 2 Diabetes - a Dose Finding Study
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The study will look at how well different doses of a new medicine called NNC0487-0111 help lower the blood sugar and body weight in people with type 2 diabetes. NNC0487-0111 is a new medicine which cannot be prescribed by doctors but has previously been tested in humans. Participants will either get NNC0487-0111, which is given as tablets or as injections, or placebo. Which treatment the participant get is decided by chance.The study will last for about 43 weeks.
Study identification
- NCT ID
- NCT06542874
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 448 participants
Conditions and interventions
Conditions
Interventions
- NNC0487-0111 subcutanous Drug
- Placebo (NNC0487-0111 subcutanous) Drug
- NNC0487-0111 oral Drug
- Placebo (NNC0487-0111 oral) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 6, 2024
- Primary completion
- Sep 30, 2025
- Completion
- Oct 23, 2025
- Last update posted
- Aug 12, 2026
2024 – 2025
United States locations
- U.S. sites
- 39
- U.S. states
- 19
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Uni of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Velocity Clin Research LA | Los Angeles | California | 90057 | — |
| Southern Cal Clinical Research | Santa Ana | California | 92701 | — |
| Chase Medical Research LLC | Waterbury | Connecticut | 06708 | — |
| Fleming Island Ctr for Clin Res | Fleming Island | Florida | 32003 | — |
| Encore Medical Research LLC | Hollywood | Florida | 33024 | — |
| South Broward Research LLC | Miramar | Florida | 33027 | — |
| Florida Inst For Clin Res | Orlando | Florida | 32825 | — |
| Florida Institute for Clinical research | Orlando | Florida | 32825 | — |
| Cedar-Crosse Research Center | Chicago | Illinois | 60607 | — |
| Cotton O'Neil Clinical Research Center | Topeka | Kansas | 66606 | — |
| Advanced Internal Medicine, PLLC | Paducah | Kentucky | 42001 | — |
| Medstar Research Institute_Hyattsville | Hyattsville | Maryland | 20782 | — |
| MD Medical Research | Oxon Hill | Maryland | 20745 | — |
| Brigham & Women's Hospital | Boston | Massachusetts | 02115 | — |
| ActivMed Practice & Research LLC | Methuen | Massachusetts | 01844 | — |
| Arcturus HC PLC Troy Med Res | Troy | Michigan | 48098 | — |
| Arcturus Healthcare, PLC | Troy | Michigan | 48098 | — |
| Clinical Research Professionals | Chesterfield | Missouri | 63005 | — |
| StudyMetrix Research LLC | City of Saint Peters | Missouri | 63303 | — |
| AMC Community Endocrinology | Albany | New York | 12203 | — |
| Centricity Rsrch MHCity Multi | Morehead City | North Carolina | 28557 | — |
| Piedmont Healthcare/Research | Statesville | North Carolina | 28625 | — |
| Lillestol Research LLC | Fargo | North Dakota | 58104 | — |
| Plains Clinical Research Center, LLC_Fargo | Fargo | North Dakota | 58104 | — |
| Alliance for Multispec Res | Norman | Oklahoma | 73069 | — |
| Jefferson Endocrinology Assocs | Philadelphia | Pennsylvania | 19107-6810 | — |
| Preferred Primary Care Physicians_Pittsburgh | Pittsburgh | Pennsylvania | 15236 | — |
| Health Concepts | Rapid City | South Dakota | 57702 | — |
| Holston Medical Group | Kingsport | Tennessee | 37660 | — |
| Clinical Research Associates | Nashville | Tennessee | 37203 | — |
| MidState Endocrine Associates | Nashville | Tennessee | 37203 | — |
| Velocity Clinical Res-Dallas | Dallas | Texas | 75230 | — |
| Victorium Clinical Research | Houston | Texas | 77024 | — |
| Synergy Groups Medical | Houston | Texas | 77061 | — |
| PlanIt Research, PLLC | Houston | Texas | 77079 | — |
| Radiance Clinical Research | Lampasas | Texas | 76550 | — |
| Tekton Research | McKinney | Texas | 75069 | — |
| Hillcrest Family Health Center | Waco | Texas | 76708 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 98 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06542874, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 12, 2026 · Synced Sep 12, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06542874 live on ClinicalTrials.gov.