ClinicalTrials.gov record
Continuation Protocol for Obstructive Sleep Apnea (OSA)
ClinicalTrials.gov ID: NCT06566820
Public ClinicalTrials.gov record NCT06566820. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Open Label Continuation Protocol of a Fixed Dose Combination of Aroxybutynin and Atomoxetine (AD109) in Obstructive Sleep Apnea
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The combination drug composed of aroxybutynin and atomoxetine, designated AD109, is being developed by Apnimed for the treatment of obstructive sleep apnea (OSA). The present study is a Phase 3 open label continuation protocol enrolling qualifying participants who completed one of the parent Phase 3 double-blind placebo-controlled studies, APC-APN-304 or APC-APN-305.
Study identification
- NCT ID
- NCT06566820
- Recruitment status
- Enrolling by invitation
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,280 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 2, 2024
- Primary completion
- Jun 29, 2026
- Completion
- Jun 29, 2026
- Last update posted
- May 12, 2025
2024 – 2026
United States locations
- U.S. sites
- 93
- U.S. states
- 29
- U.S. cities
- 83
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Sleep Disorders Center of America | Birmingham | Alabama | 35213 | — |
| The University of Alabama/Institute for Rural Health Research | Tuscaloosa | Alabama | 35401 | — |
| Chandler Clinical Trials | Chandler | Arizona | 85224 | — |
| Desert Clinical Reserach, LLC/CCT Research | Mesa | Arizona | 85213 | — |
| Foothills Research Center/CCT Research | Phoenix | Arizona | 85044 | — |
| Fiel Family and Sports Medicine/CCT Research | Tempe | Arizona | 85283 | — |
| Noble Clinical Research | Tucson | Arizona | 85704 | — |
| Preferred Research Partners, Inc. | Little Rock | Arkansas | 72211 | — |
| Orange County Research Institute | Anaheim | California | 92801 | — |
| Core Healthcare Group | Cerritos | California | 90703 | — |
| Exalt Clinical Research, Inc. | Chula Vista | California | 91910 | — |
| Collaborative Neuroscience Research, LLC | Los Alamitos | California | 90720 | — |
| Santa Monica Clinical Trials | Los Angeles | California | 90025 | — |
| Empire Clinical Research | Pomona | California | 91767 | — |
| Probe Clinical Research Corporation | Riverside | California | 92501 | — |
| Pacific Research Network | San Diego | California | 92103 | — |
| TriValley Sleep Center | San Ramon | California | 94583 | — |
| SDS Clinical Trials, Inc. | Santa Ana | California | 92705 | — |
| Providere Research Inc. | West Covina | California | 91790 | — |
| Mountain View Clinical Research, Inc. | Denver | Colorado | 80209 | — |
| Meris Clinical Research | Brandon | Florida | 33511 | — |
| Teradan Clinical Trials | Brandon | Florida | 33511 | — |
| St. Francis Medical Institute | Clearwater | Florida | 33765 | — |
| Nouvelle Clinical Research | Cutler Bay | Florida | 33189 | — |
| Arrow Clinical Trials | Daytona Beach | Florida | 32117 | — |
| Canvas Clinical Research | Lake Worth | Florida | 33467 | — |
| Florida Lung & Sleep Associates | Lehigh Acres | Florida | 33971 | — |
| Ivetmar Medical Group, LLC | Miami | Florida | 33155 | — |
| Advanced Medical Research Institute | Miami | Florida | 33174 | — |
| PharmaDev Clinical Research Institute, LLC | Miami | Florida | 33176 | — |
| Flourish Research | Miami | Florida | 33186 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Clinical Neuroscience Solutions, Inc. | Orlando | Florida | 32801 | — |
| JSV Clinical Research Study Inc. | Tampa | Florida | 33634 | — |
| Palm Beach Research Center | West Palm Beach | Florida | 33409 | — |
| Central Florida Pediatric Sleep Disorders d/b/a Florida Pediatric Institute, LLC | Winter Park | Florida | 32789 | — |
| Clinical Site Partners, LLC dba Flourish Research | Winter Park | Florida | 32789 | — |
| Neurotrials Research Inc | Atlanta | Georgia | 30328 | — |
| Atlanta Center for Medical Research | Atlanta | Georgia | 30331 | — |
| CenExel iResearch, LLC | Decatur | Georgia | 30030 | — |
| Georgia Neurology and Sleep Medicine Associates | Suwanee | Georgia | 30024 | — |
| Medster Research | Valdosta | Georgia | 31605 | — |
| St. Luke's Idaho Pulmonary Associates - Meridian Clinic | Meridian | Idaho | 83642 | — |
| Chicago Research Center, Inc. | Chicago | Illinois | 60634 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Advanced ENT and Allergy | Louisville | Kentucky | 40220 | — |
| Centennial Medical Group Research Department | Columbia | Maryland | 21045 | — |
| Sleep Disorders Centers of the Mid-Atlantic | Glen Burnie | Maryland | 21061 | — |
| Velocity Clinical Research | Rockville | Maryland | 20854 | — |
| Neurocare, Inc. | Newton | Massachusetts | 02459 | — |
| Infinity Medical Research | North Dartmouth | Massachusetts | 02747 | — |
| Baystate Clinical Trials Unit | Springfield | Massachusetts | 01107 | — |
| University of Michigan Clinical Research Unit | Ann Arbor | Michigan | 48109 | — |
| Revive Research Institute, Inc. | Lathrup Village | Michigan | 48076 | — |
| Henry Ford Medical Center - Columbus | Novi | Michigan | 48377 | — |
| Clinical Neurophysiology Services PC | Sterling Heights | Michigan | 48314 | — |
| Sleep Medicine and Research Center, St. Luke's Hospital | Chesterfield | Missouri | 63017 | — |
| Healthcare Research Network | Hazelwood | Missouri | 63042 | — |
| Clayton Sleep Institute, LLC | St Louis | Missouri | 63123 | — |
| Henderson Clinical Trials | Henderson | Nevada | 89052 | — |
| Las Vegas Clinical Trials, LLC | North Las Vegas | Nevada | 89030 | — |
| Clinilabs Drug Development Corporation | Eatontown | New Jersey | 07724 | — |
| Sleep Dynamics | Neptune City | New Jersey | 07753 | — |
| Maimonides Sleep Arts & Sciences | Albuquerque | New Mexico | 87107 | — |
| Northwell Health | New Hyde Park | New York | 11042 | — |
| Research Carolina Elite | Denver | North Carolina | 28037 | — |
| Clinical Research of Gastonia | Gastonia | North Carolina | 28054 | — |
| Peters Medical Research LLC | High Point | North Carolina | 27260 | — |
| Advanced Respiratory and Sleep Medicine | Huntersville | North Carolina | 28078 | — |
| Coastal Carolina Health Care, P.A. Pulmonary and Sleep Medicine | New Bern | North Carolina | 28562 | — |
| Accellacare | Wilmington | North Carolina | 28412 | — |
| Lillestol Research | Fargo | North Dakota | 58104 | — |
| NeuroScience Research Center, LLC | Canton | Ohio | 44718 | — |
| CTI Clinical Research Center | Cincinnati | Ohio | 45212 | — |
| Intrepid Research, LLC | Cincinnati | Ohio | 45245 | — |
| Northwest Research Center | Portland | Oregon | 97202 | — |
| Abington Neurological Associates | Abington | Pennsylvania | 19001 | — |
| Respiratory Specialists | Wyomissing | Pennsylvania | 19610 | — |
| Lowcountry Lung and Critical Care, PA | Charleston | South Carolina | 29406 | — |
| Tribe Clinical Research, LLC | Greenville | South Carolina | 29607 | — |
| Velocity Clinical Research, Greenville | Greenville | South Carolina | 29615 | — |
| OnSite Clinical Solutions, LLC | Rock Hill | South Carolina | 29732 | — |
| Chattanooga Research & Medicine | Chattanooga | Tennessee | 37404 | — |
| Clinical Neuroscience Solutions, Inc. | Memphis | Tennessee | 38119 | — |
| FutureSearch Trials of Neurology | Austin | Texas | 78731 | — |
| FutureSearch Trials of Dallas | Dallas | Texas | 75231 | — |
| Memorial Hermann Village | Houston | Texas | 77043 | — |
| Houston Clinical Research Associates | Houston | Texas | 77070 | — |
| Huntsville Research Institute | Huntsville | Texas | 77340 | — |
| Sleep Therapy and Research Center | San Antonio | Texas | 78229 | — |
| Element Research Group | San Antonio | Texas | 78258 | — |
| South Ogden Family Medicine/CCT Research | South Ogden | Utah | 84405 | — |
| Sleep Disorder Center of the Mid-Atlantic | Vienna | Virginia | 22182 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06566820, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 12, 2025 · Synced Sep 4, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06566820 live on ClinicalTrials.gov.