Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Psoriatic Arthritis and Obesity or Overweight
Public ClinicalTrials.gov record NCT06588296. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy and Safety of Ixekizumab or Ixekizumab Concomitantly Administered With Tirzepatide in Adult Participants With Active Psoriatic Arthritis and Obesity or Overweight: A Phase 3b, Randomized, Multicenter, Open-Label Study (TOGETHER-PsA)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study is to demonstrate that when participants with psoriatic arthritis and obesity or overweight in the presence of at least 1 weight-related comorbid condition receive ixekizumab and tirzepatide concomitantly administered, participants see improvement in their psoriatic arthritis and achieve weight reduction compared to when receiving ixekizumab. Participation in this study includes up to 12 visits and could last up to 61 weeks including screening, open label treatment period, and post-treatment follow-up period.
Study identification
- NCT ID
- NCT06588296
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 279 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 24, 2024 (Actual)
- Primary completion
- Nov 18, 2025 (Actual)
- Completion
- Apr 23, 2026 (Actual)
- Last update posted
- May 13, 2026
2024 – 2026
United States locations
- U.S. sites
- 81
- U.S. states
- 28
- U.S. cities
- 78
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Avondale | Avondale | Arizona | 85392 | — |
| AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Chandler | Chandler | Arizona | 85225 | — |
| AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Flagstaff | Flagstaff | Arizona | 86001 | — |
| AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Gilbert | Gilbert | Arizona | 85297 | — |
| AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Glendale | Glendale | Arizona | 85306 | — |
| AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Mesa | Mesa | Arizona | 85210 | — |
| AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Phoenix PV | Phoenix | Arizona | 85032 | — |
| AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Sun City | Sun City | Arizona | 85351 | — |
| AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Tucson | Tucson | Arizona | 85704 | — |
| AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Tucson Southeast | Tucson | Arizona | 85748 | — |
| Medvin Clinical Research - Apple Valley | Apple Valley | California | 92307 | — |
| Medvin Clinical Research - Covina | Covina | California | 91722 | — |
| Newport Huntington Medical Group | Huntington Beach | California | 92648 | — |
| Purushotham & Akther Kotha MD, Inc | La Mesa | California | 91942 | — |
| Medvin Clinical Research - Riverside | Riverside | California | 92508 | — |
| Rheumatology Center of San Diego | San Diego | California | 92128 | — |
| Medvin Clinical Research - Temecula | Temecula | California | 92592 | — |
| Cohen Medical Centers | Thousand Oaks | California | 91360 | — |
| Medvin Clinical Research - Tujunga | Tujunga | California | 91042 | — |
| Medvin Clinical Research - Whittier | Whittier | California | 90602 | — |
| Denver Arthritis Clinic | Denver | Colorado | 80230 | — |
| Clinical Research of West Florida, Inc. (Clearwater) | Clearwater | Florida | 33765 | — |
| NeoClinical Research | Hialeah | Florida | 33016 | — |
| South Florida Rheumatology | Hollywood | Florida | 33021 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| Vida Clinical Research | Kissimmee | Florida | 34741 | — |
| Life Clinical Trials | Margate | Florida | 33063 | — |
| Suncoast Clinical Research, Inc. | New Port Richey | Florida | 34652 | — |
| Vitalia Medical Research | Palm Beach Gardens | Florida | 33410 | — |
| Sarasota Arthritis Center | Sarasota | Florida | 34239 | — |
| Clinical Research of West Florida | Tampa | Florida | 33606 | — |
| International Center for Research | Tampa | Florida | 33614 | — |
| Conquest Research | Winter Park | Florida | 32789 | — |
| Southeastern Rheumatology Alliance dba Arthritis Center of North Georgia | Gainesville | Georgia | 30501 | — |
| Atlanta Research Center for Rheumatology | Marietta | Georgia | 30060 | — |
| St. Luke's Clinic | Boise | Idaho | 83702 | — |
| Great Lakes Clinical Trials - Ravenswood | Chicago | Illinois | 60640 | — |
| Greater Chicago Specialty Physicians | Schaumburg | Illinois | 60195 | — |
| Arnold Arthritis & Rheumatology | Skokie | Illinois | 60076 | — |
| Willow Rheumatology and Wellness PLLC | Willowbrook | Illinois | 60527 | — |
| Qualmedica Research, LLC | Evansville | Indiana | 47715 | — |
| Alliance for Multispecialty Research, LLC | Wichita | Kansas | 67207 | — |
| Accurate Clinical Research, Inc | Lake Charles | Louisiana | 70605 | — |
| Klein & Associates, M.D., P.A. | Cumberland | Maryland | 21502 | — |
| Klein & Associates, M.D., P.A. | Hagerstown | Maryland | 21740 | — |
| NECCR PrimaCare Research | Fall River | Massachusetts | 02721 | — |
| Advanced Rheumatology, PC | Okemos | Michigan | 48864 | — |
| Saint Paul Rheumatology | Eagan | Minnesota | 55121 | — |
| AARA Clinical Research - Kansas City Physician Partners - North | Kansas City | Missouri | 64151 | — |
| Clinvest Headlands Llc | Springfield | Missouri | 65807 | — |
| Arthritis Consultants, Inc. | St Louis | Missouri | 63141 | — |
| Logan Health Research | Kalispell | Montana | 59901 | — |
| Physician Research Collaboration, LLC | Lincoln | Nebraska | 68516 | — |
| Albuquerque Center for Rheumatology | Albuquerque | New Mexico | 87102 | — |
| Inspire Santa Fe Medical Group | Santa Fe | New Mexico | 87505 | — |
| St. Lawrence Health System | Canton | New York | 13617 | — |
| Onsite Clinical Solutions, LLC - Brenner Ave | Salisbury | North Carolina | 28144 | — |
| Paramount Medical Research & Consulting, LLC | Middleburg Heights | Ohio | 44130 | — |
| RAO Research LLC | Oklahoma City | Oklahoma | 73116 | — |
| Essential Medical Research | Tulsa | Oklahoma | 74137 | — |
| Summit Headlands | Portland | Oregon | 97210 | — |
| Altoona Center For Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| West Tennessee Research Institute | Jackson | Tennessee | 38305 | — |
| AARA Clinical Research - Murfreesboro Medical Clinic | Murfreesboro | Tennessee | 37128 | — |
| Tekton Research, LLC. | Austin | Texas | 78745 | — |
| Accurate Clinical Management, LLC | Baytown | Texas | 77521 | — |
| Precision Comprehensive Clinical Research Solutions - Colleyville | Colleyville | Texas | 76034 | — |
| Arthritis Care of Texas | Corpus Christi | Texas | 78415 | — |
| AARA Clinical Research - Lone Star Arthritis and Rheumatology Associates - Fort Worth | Fort Worth | Texas | 76109 | — |
| Accurate Clinical Research, Inc | Houston | Texas | 77089 | — |
| Research Physicians Network, LLC | Houston | Texas | 77089 | — |
| AARA Clinical Research - Lone Star Arthritis and Rheumatology Associates - Irving | Irving | Texas | 75039 | — |
| Biopharma Informatic, LLC | Katy | Texas | 77494 | — |
| West Texas Clinical Research | Lubbock | Texas | 79424 | — |
| Valley Arthritis Center | McAllen | Texas | 78501 | — |
| SouthWest Rheumatology Research, LLC | Mesquite | Texas | 75150 | — |
| Advanced Rheumatology of Houston - Woodlands | The Woodlands | Texas | 77382 | — |
| DM Clinical Research - TRA | Tomball | Texas | 77375 | — |
| Overlake Arthritis and Osteoporosis Center | Bellevue | Washington | 98004 | — |
| Arthritis Northwest, PLLC | Spokane | Washington | 99204 | — |
| Rheumatology & Pulmonary Clinic | Beckley | West Virginia | 25801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06588296, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 13, 2026 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06588296 live on ClinicalTrials.gov.