A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis
Public ClinicalTrials.gov record NCT06588855. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Multicenter, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Induction Therapy With RO7790121 in Patients With Moderately to Severely Active Ulcerative Colitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This Phase III, multicenter, double-blind, placebo-controlled study will evaluate the efficacy and safety of induction therapy with Afimkibart (RO7790121) compared with placebo in participants with moderately to severely active ulcerative colitis (UC).
Study identification
- NCT ID
- NCT06588855
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 350 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 16 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 11, 2024 (Actual)
- Primary completion
- Oct 29, 2026 (Estimated)
- Completion
- Jan 30, 2031 (Estimated)
- Last update posted
- Oct 2, 2026
2024 – 2031
United States locations
- U.S. sites
- 64
- U.S. states
- 22
- U.S. cities
- 55
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Digestive Health Specialists of the Southeast (Gastroenterology Associates of Dothan) - Dothan | Dothan | Alabama | 36305 | — |
| Mayo Clinic Hospital | Scottsdale | Arizona | 85259 | — |
| Arizona Digestive Health, P.C (ADH) | Sun City | Arizona | 85351 | — |
| Om Research LLC | Apple Valley | California | 92307 | — |
| Valley View Internal Medicine | Garden Grove | California | 92845 | — |
| Gastro Care Associates | Lancaster | California | 93534 | — |
| Stanford Medicine Outpatient Center | Redwood City | California | 94063 | — |
| Peak Gastroenterology Associates | Colorado Springs | Colorado | 80907 | — |
| Hi Tech and Global Research, LLC | Coral Gables | Florida | 33134 | — |
| The Sister Life Research | Hialeah | Florida | 33013 | — |
| LCC Medical Research Institute, LLC | Miami | Florida | 33126 | — |
| Allied Biomedical Research Institute | Miami | Florida | 33155 | — |
| Integrity Trials LLC | Orlando | Florida | 32807 | — |
| Digestive and Liver Center of Florida | Orlando | Florida | 32825 | — |
| Advanced Medical Research Center | Port Orange | Florida | 32127 | — |
| University of South Florida School of Medicine Morsani Center for Advanced Health Care | Tampa | Florida | 33612 | — |
| Guardian Angel Research Center, LLC | Tampa | Florida | 33614 | — |
| Santos Research Center, CORP | Tampa | Florida | 33615 | — |
| Cleveland Clinic Florida | Weston | Florida | 33331 | — |
| Randomize Now, LLC | Atlanta | Georgia | 30308 | — |
| Atlanta Gastroenterology Associates | Atlanta | Georgia | 30342 | — |
| Gastroenterology Associates of Central Georgia | Macon | Georgia | 31201 | — |
| Illinois Gastroenterology Group-Glenview powered by GI Alliance | Glenview | Illinois | 60026 | — |
| GI Alliance - Gurnee | Gurnee | Illinois | 60031 | — |
| Gastro Health Partners, LLC | New Albany | Indiana | 47150 | — |
| Kansas Gastroenterology, LLC under Clinical Trials Network | Wichita | Kansas | 67226 | — |
| One GI: GHP - Gastroenterology Health Partners Louisville | Louisville | Kentucky | 40218 | — |
| Louisiana Research Center - GastroIntestinal Associates | Shreveport | Louisiana | 71105 | — |
| Allied Gastrointestinal Associates, PA | Flowood | Mississippi | 39232 | — |
| Dartmouth-Hitchcock Medical Center-Norris Cotton Cancer Center | Lebanon | New Hampshire | 03756 | — |
| Ellipsis Research Group | Brooklyn | New York | 11215 | — |
| NYU Inflammatory Bowel Disease Center | New York | New York | 10016 | — |
| Weill Cornell Medical College | New York | New York | 10021 | — |
| DiGiovanna Inst for Med Ed&Res | North Massapequa | New York | 11758 | — |
| Queens Village Medical Care | Queens Village | New York | 11428 | — |
| Gastroenterology Group Of Rochester, LLP | Rochester | New York | 14618 | — |
| Charlotte Gastroenterology and Hepatology, P.L.L.C | Charlotte | North Carolina | 28207 | — |
| Omega Research North Carolina, LLC | Fuquay-Varina | North Carolina | 27526 | — |
| Peters Medical Research (PMR), LLC | High Point | North Carolina | 27260 | — |
| Dayton Gastroenterology, Inc. | Beavercreek | Ohio | 45440 | — |
| University of Cincinnati Hospital | Cincinnati | Ohio | 45267 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Ohio Gastroenterology Group | Columbus | Ohio | 43202 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Gastro Intestinal Research Institute of Northern Ohio | Westlake | Ohio | 44145 | — |
| Frontier Clinical Re search, LLC | Uniontown | Pennsylvania | 15401 | — |
| University Gastroenterology | Providence | Rhode Island | 02904 | — |
| Gastroenterology Associates | Greenville | South Carolina | 29607 | — |
| Gastro One | Cordova | Tennessee | 38018 | — |
| Uni of Texas Medical Branch | Galveston | Texas | 77555 | — |
| GI Alliance | Garland | Texas | 75044 | — |
| Amel Med LLC | Georgetown | Texas | 78628 | — |
| Cano Medical Center | Harlingen | Texas | 78550 | — |
| Texas Digestive Specialists | Harlingen | Texas | 78550 | — |
| GI Alliance - Bay Area Gastroenterology | Lubbock | Texas | 79410 | — |
| TDDC dba GI Alliance Research | Mansfield | Texas | 76063 | — |
| Southern Star Research Institute, LLC. | San Antonio | Texas | 78229 | — |
| Baylor Scott and White Medical Center | Temple | Texas | 76508 | — |
| Tyler Research Institute, LLC | Tyler | Texas | 75701 | — |
| University of Texas Health Center at Tyler | Tyler | Texas | 75708 | — |
| TDDC GI Alliance research Webster | Webster | Texas | 77598 | — |
| Gastroenterology Associates of Tidewater | Chesapeake | Virginia | 23320 | — |
| Emeritas Research Group | Lansdowne Town Center | Virginia | 20176 | — |
| Gastroenterology Consultants of SWVA | Roanoke | Virginia | 24018 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 104 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06588855, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 2, 2026 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06588855 live on ClinicalTrials.gov.