A Study to Investigate the Efficacy and Safety of NSI-8226 in Adults With Eosinophilic Esophagitis
Public ClinicalTrials.gov record NCT06598462. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-Blind, Multicenter, Placebo Controlled Study With an Extension to Investigate the Efficacy and Safety of NSI-8226 in Adults With Eosinophilic Esophagitis (ALAMERE)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Phase 2 study to evaluate the safety, tolerability, PK, immunogenicity, and pharmacodynamics of solrikitug in adult participants with eosinophilic esophagitis.
Study identification
- NCT ID
- NCT06598462
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 184 participants
Conditions and interventions
Conditions
Interventions
- Solrikitug Low Dose Biological
- Solrikitug Mid Dose Biological
- Solrikitug High Dose Biological
- Placebo Other
Biological · Other
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 16, 2024 (Actual)
- Primary completion
- Apr 30, 2027 (Estimated)
- Completion
- Aug 31, 2027 (Estimated)
- Last update posted
- Mar 20, 2026
2024 – 2027
United States locations
- U.S. sites
- 38
- U.S. states
- 22
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site 1039 | Dothan | Alabama | 36305 | — |
| Research Site 1018 | Glendale | Arizona | 85306 | — |
| Research Site 1018 | Peoria | Arizona | 85306 | — |
| Research Site 1037 | Scottsdale | Arizona | 85258 | — |
| Research Site 1003 | Tucson | Arizona | 85715 | — |
| Research Site 1023 | Englewood | California | 90301 | — |
| Research Site 1005 | Irvine | California | 92618 | — |
| Research Site 1015 | San Diego | California | 92120 | — |
| Research Site 1034 | Aurora | Colorado | 80045 | — |
| Research Site 1027 | Cromwell | Connecticut | 06416 | — |
| Research Site 1040 | Inverness | Florida | 34452 | — |
| Research Site 1001 | Jacksonville | Florida | 32256 | — |
| Research Site 1049 | Miami | Florida | 33155 | — |
| Research Site 1007 | Boise | Idaho | 83706 | — |
| Research Site 1048 | Glenview | Illinois | 60026 | — |
| Research Site 1022 | Iowa City | Iowa | 52242 | — |
| Research Site 1033 | Topeka | Kansas | 66606 | — |
| Research Site 1032 | Chevy Chase | Maryland | 20815 | — |
| Research Site 1004 | Boston | Massachusetts | 02111 | — |
| Research Site 1024 | Ann Arbor | Michigan | 48109 | — |
| Research Site 1013 | Wyoming | Michigan | 49519 | — |
| Research Site 1006 | Plymouth | Minnesota | 55446 | — |
| Research Site 1042 | Creve Coeur | Missouri | 63141 | — |
| Research Site 1016 | Reno | Nevada | 89511 | — |
| Research Site 1045 | Freehold | New Jersey | 07728 | — |
| Research Site 1043 | Jackson | New Jersey | 08527 | — |
| Research Site 1026 | Chapel Hill | North Carolina | 27599 | — |
| Research Site 1021 | High Point | North Carolina | 27265 | — |
| Research Site 1012 | Columbus | Ohio | 43213 | — |
| Research Site 1020 | Harrisburg | Pennsylvania | 17110 | — |
| Research Site 1030 | Philadelphia | Pennsylvania | 19104 | — |
| Research Site 1014 | Dallas | Texas | 75230 | — |
| Research Site 1008 | Houston | Texas | 77494 | — |
| Research Site 1036 | Pearland | Texas | 77584 | — |
| Research Site 1041 | Rockwell | Texas | 75032 | — |
| Research Site 1002 | Ogden | Utah | 84405 | — |
| Research Site 1019 | Salt Lake City | Utah | 84132 | — |
| Research Site 1017 | Sandy City | Utah | 84092 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 35 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06598462, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 20, 2026 · Synced Oct 30, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06598462 live on ClinicalTrials.gov.