A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

ClinicalTrials.gov ID: NCT06598943

Public ClinicalTrials.gov record NCT06598943. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 8, 2026, 7:56 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Adaptive, Dose-Ranging, Phase 2 Study of Eltrekibart Given Alone or in Combination With Mirikizumab for the Treatment of Adult Patients With Moderately to Severely Active Ulcerative Colitis

Study identification

NCT ID: NCT06598943
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Eli Lilly and Company; Industry
Enrollment: 140 participants

Conditions and interventions

Conditions

Interventions

Eltrekibart Drug
Mirikizumab Drug
Placebo Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 75 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Oct 9, 2024
Primary completion: Nov 30, 2027
Completion: Aug 31, 2028
Last update posted: Apr 19, 2026

2024 – 2028

United States locations

U.S. sites: 46
U.S. states: 15
U.S. cities: 38

Facility	City	State	ZIP	Site status
AZ Gastro Care - Chandler	Chandler	Arizona	85225	Not yet recruiting
Applied Research Center of Arkansas	Little Rock	Arkansas	72205	Recruiting
Preferred Research Partners	Little Rock	Arkansas	72211	Not yet recruiting
Erick Alayo Medical Corp/Gastro SB Clinic	Chula Vista	California	91910	Recruiting
Southern California GI and Liver Centers (SCLC)	Coronado	California	92118	Recruiting
Valley View Research	Garden Grove	California	92845	Recruiting
Om Research, LLC	Lancaster	California	93534	Recruiting
United Medical Doctors	Los Alamitos	California	90720-3433	Recruiting
Clinnova Research	Orange	California	92868-4402	Recruiting
Prospective Research Innovations	Rancho Cucamonga	California	91730-4850	Recruiting
Clinical Trials Management Services, LLC	Thousand Oaks	California	91360	Recruiting
Om Research LLC	Victorville	California	92395	Recruiting
Peak Gastroenterology Associates	Colorado Springs	Colorado	80907-6262	Recruiting
Medical Research Center of Connecticut, LLC	Hamden	Connecticut	06518-3602	Recruiting
Novum Research, LLC	Clermont	Florida	34711	Not yet recruiting
I.V.A.M. Clinical & Investigational Center, LLC	Doral	Florida	33126	Not yet recruiting
Florida Research Institute	Lakewood Rch	Florida	34211	Not yet recruiting
Well Pharma Medical Research Corp.	Miami	Florida	33173	Recruiting
Reserka	Miami	Florida	33176	Not yet recruiting
Digestive Disease Consultants DDCJAX	Orange Park	Florida	32073-4752	Not yet recruiting
Orlando Health Digestive Health Institute	Orlando	Florida	32803-1248	Recruiting
AdventHealth Orlando	Orlando	Florida	32803	Not yet recruiting
Nodal Medical Center	Tampa	Florida	33607	Recruiting
Research Bay,Inc.	Tampa	Florida	33607	Recruiting
GCP Clinical Research, LLC	Tampa	Florida	33609	Recruiting
International Center for Research LLC	Tampa	Florida	33614	Recruiting
Northwestern University	Chicago	Illinois	60611	Not yet recruiting
Avicenna Clinical Research - SW Gastroenterology	Oak Lawn	Illinois	60453-3754	Recruiting
Clinical Trials Management, LLC	Metairie	Louisiana	70006	Not yet recruiting
Gastroenterology Associates of Western Michigan, P.L.C.	Wyoming	Michigan	49519	Recruiting
Ellipsis Research Group	Brooklyn	New York	11215	Recruiting
Smart Medical Research - Jackson Heights	Jackson Heights	New York	11372	Recruiting
Pioneer Clinical Research NY	New York	New York	10012-3645	Recruiting
Digestive Disease Medicine of Central New York	Utica	New York	13502	Recruiting
University of North Carolina	Chapel Hill	North Carolina	27599	Recruiting
GCGA Physicians, LLC dba / Gastro Health Research	Cincinnati	Ohio	45219	Recruiting
NexGen Research	Lima	Ohio	45801	Recruiting
Inquest Clinical Research	Baytown	Texas	77521	Recruiting
DHR Health Gastroenterology - Edinburg	Edinburg	Texas	78539	Recruiting
Baylor College of Medicine	Houston	Texas	77030	Recruiting
Intergrity Research	Houston	Texas	77043	Recruiting
Gastroenterology Research of San Antonio	San Antonio	Texas	78229	Recruiting
Tyler Research Institute	Tyler	Texas	75701	Recruiting
Care Access-Ogden	Ogden	Utah	84403	Recruiting
Advanced Research Institute - South Ogden	Ogden	Utah	84405	Recruiting
University of Washington School Medicine	Seattle	Washington	98195	Not yet recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 161 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06598943, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 19, 2026 · Synced May 8, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06598943 live on ClinicalTrials.gov.

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