A Study to Evaluate the Efficacy and Safety of GDC-8264 in Preventing Cardiac Surgery-Associated Acute Kidney Injury (AKI) and Major Adverse Kidney Events (MAKE)
Public ClinicalTrials.gov record NCT06602453. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of GDC-8264 in Preventing Cardiac Surgery-Associated Acute Kidney Injury and Major Adverse Kidney Events
Study identification
- NCT ID
- NCT06602453
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Genentech, Inc.
- Industry
- Enrollment
- 67 participants
Conditions and interventions
Conditions
Interventions
- GDC-8264 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 16, 2025
- Primary completion
- Mar 2, 2026
- Completion
- Mar 2, 2026
- Last update posted
- Mar 15, 2026
2025 – 2026
United States locations
- U.S. sites
- 9
- U.S. states
- 9
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Stanford Medical Center | Stanford | California | 94305-2200 | — |
| James A Haley Veteran Affairs Medical Center - NAVREF - PPDS | Tampa | Florida | 33612-4745 | — |
| John Hopkins Hospital | Lutherville | Maryland | 21093 | — |
| Baystate Cardiac Surgery | Springfield | Massachusetts | 01107 | — |
| Mayo Clinic - PPDS | Rochester | Minnesota | 55905-0001 | — |
| CHI Health Nebraska Heart | Lincoln | Nebraska | 68526-9437 | — |
| Duke University Medical Center | Durham | North Carolina | 27705 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390-7202 | — |
| Richmond VA Medical Center NAVREF PPDS | Richmond | Virginia | 99999 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 25 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06602453, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 15, 2026 · Synced May 16, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06602453 live on ClinicalTrials.gov.