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Terminated Phase 2Phase 3 Interventional

Study of Oral Weekly GS-1720 and GS-4182 Compared With Biktarvy in People With HIV-1 Who Have Not Been Treated

ClinicalTrials.gov ID: NCT06613685

Public ClinicalTrials.gov record NCT06613685. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 19, 2026, 8:23 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Operationally Seamless Phase 2/3, Randomized, Active-Controlled Study Evaluating the Safety and Efficacy of an Oral Weekly Regimen of GS-1720 in Combination With GS-4182 Versus Biktarvy in Treatment-Naive People With HIV-1

Study identification

NCT ID
NCT06613685
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
Gilead Sciences
Industry
Enrollment
73 participants

Conditions and interventions

Interventions

  • Bictegravir/emtricitabine/tenofovir alafenamide Drug
  • Placebo to Match BVY Drug
  • Placebo to Match GS1720/GS-4182 FDC Drug
  • lenacapavir pacfosacil Drug
  • lepetegravir Drug
  • lepetegravir/lenacapavir pacfosacil FDC Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 20, 2024
Primary completion
Mar 15, 2026
Completion
Mar 15, 2026
Last update posted
Apr 14, 2026

2024 – 2026

United States locations

U.S. sites
21
U.S. states
11
U.S. cities
20
Facility City State ZIP Site status
UAB 1917 Research Clinic Birmingham Alabama 35222
The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center Torrance California 90502
Mills Clinical Research West Hollywood California 90046
Georgetown University Medical School Washington D.C. District of Columbia 20007
Midland Florida Clinical Research Center, LLC DeLand Florida 32720
Midway Immunology and Research Center Ft. Pierce Florida 34982
Floridian Clinical Research, LLC Miami Lakes Florida 33016
Orlando Immunology Center Orlando Florida 32803
Triple O Research Institute, P.A. West Palm Beach Florida 33407
Emory University Hospital Midtown Infectious Disease Clinic Atlanta Georgia 30308
Mercer University, Department of Internal Medicine Macon Georgia 31201
University of Mississippi Medical Center Jackson Mississippi 39216
Saint Michael's Medical Center Newark New Jersey 07102
NYU Langone Health Vaccine Center New York New York 10016
Medical University of South Carolina (MUSC) Research Nexus Charleston South Carolina 29425
St Hope Foundation, Inc. Bellaire Texas 77401
Prism Health North Texas, Aids Arms Dallas Texas 75208
North Texas Infectious Diseases Consultants, PA Dallas Texas 75246
Texas Centers for Infectious Disease Associates Fort Worth Texas 76104
UT Health San Antonio San Antonio Texas 78229
MultiCare Rockwood Main Clinic Spokane Washington 99202

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 37 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06613685, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 14, 2026 · Synced May 19, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06613685 live on ClinicalTrials.gov.

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