An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Active Thyroid Eye Disease (TED)
Public ClinicalTrials.gov record NCT06625411. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
REVEAL-1 - A Phase 3, Randomized, Double-masked, Placebo-controlled, Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Active Thyroid Eye Disease (TED)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a clinical trial assessing the efficacy, safety, and tolerability of an investigational drug, VRDN-003, in participants with active Thyroid Eye Disease (TED).
Study identification
- NCT ID
- NCT06625411
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 132 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 27, 2024 (Actual)
- Primary completion
- Feb 12, 2026 (Actual)
- Completion
- Nov 15, 2026 (Estimated)
- Last update posted
- Aug 18, 2026
2024 – 2026
United States locations
- U.S. sites
- 34
- U.S. states
- 14
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Scottsdale Clinical Trials | Scottsdale | Arizona | 85260 | — |
| Alliance Research Institute - Canoga Park | Canoga Park | California | 91304 | — |
| Marvel Clinical Research | Huntington Beach | California | 92647 | — |
| United Medical Research Institute | Inglewood | California | 90301 | — |
| Advancing Research International, LLC | Los Angeles | California | 90023 | — |
| Roski Eye Institute, Keck School of Medicine, USC | Los Angeles | California | 90033 | — |
| Alliance Research Institute - Lynwood | Lynwood | California | 90262 | — |
| A.P.J. Office | Newport Beach | California | 92660 | — |
| Byers Eye Institute at Stanford University | Palo Alto | California | 94303 | — |
| Pasadena Clinical Trials | Pasadena | California | 91101 | — |
| Cockerham Eye Consultants, PC | San Diego | California | 92108 | — |
| C&A Clinical Trials Corp | Cape Coral | Florida | 33990 | — |
| Ilumina Medical Research | Kissimmee | Florida | 34744 | — |
| Med-Care Research | Miami | Florida | 33125 | — |
| Continental Clinical Research | Miami | Florida | 33144 | — |
| Hype Clinical Research LLC | Miami | Florida | 33145 | — |
| Anmed Health Services LLC | Miami | Florida | 33193 | — |
| Sarasota Retina Institute | Sarasota | Florida | 34239 | — |
| Agile Clinical Research Trials, LLC | Atlanta | Georgia | 30328 | — |
| Vision Medical Research | Orland Park | Illinois | 60462 | — |
| Opthalmic Consultants of Boston | East Weymouth | Massachusetts | 02189 | — |
| Fraser Eye Care Center | Fraser | Michigan | 48026 | — |
| Kahana Oculoplastic & Orbital Surgery | Livonia | Michigan | 48152 | — |
| University Health | Kansas City | Missouri | 64108 | — |
| S.L. Office | Las Vegas | Nevada | 89144 | — |
| Vector Clinical Trials | Sparks | Nevada | 89436 | — |
| Rutgers New Jersey Medical School | Newark | New Jersey | 07103 | — |
| Asheville Clinical Research | Asheville | North Carolina | 28803 | — |
| Duke Eye Center | Durham | North Carolina | 27705 | — |
| Baylor College of Medicine/Alkek Eye Center | Houston | Texas | 77030 | — |
| Gulf Coast Clinical Trials | Houston | Texas | 77070 | — |
| Neuro-Eye Clinical Trials | Houston | Texas | 77074 | — |
| University of Washington, Eye institute | Seattle | Washington | 98104 | — |
| West Virginia University Eye Institute | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06625411, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 18, 2026 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06625411 live on ClinicalTrials.gov.