A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer
Public ClinicalTrials.gov record NCT06638307. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1, First-in-Human Study of MEN2312, a KAT6 Inhibitor, as Monotherapy and in Combination in Participants With Advanced Breast Cancer
Study identification
- NCT ID
- NCT06638307
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Stemline Therapeutics, Inc.
- Industry
- Enrollment
- 240 participants
Conditions and interventions
Conditions
Interventions
- Elacestrant Drug
- MEN2312 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 24, 2024
- Primary completion
- May 31, 2026
- Completion
- Sep 30, 2026
- Last update posted
- May 11, 2026
2024 – 2026
United States locations
- U.S. sites
- 32
- U.S. states
- 19
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Highlands Oncology Group | Springdale | Arkansas | 72703 | Recruiting |
| City of Hope | Duarte | California | 31010 | Recruiting |
| UC San Diego Moores Cancer Center | La Jolla | California | 92093-0698 | Recruiting |
| Stanfod Cancer Center | Palo Alto | California | 94304 | Recruiting |
| UCSF Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94158 | Recruiting |
| UCLA Hematology Oncology - Parkside | Santa Monica | California | 90404 | Recruiting |
| Yale Comprehensive Cancer Center | New Haven | Connecticut | 06511 | Recruiting |
| Advent Health Orlando | Altamonte Springs | Florida | 32701 | Recruiting |
| Sarah Cannon Research Institute at Florida Cancer Specialists | Orlando | Florida | 32827 | Recruiting |
| Florida Cancer Specialists & Research Institute (FCS) - Sarasota | Sarasota | Florida | 34232 | Recruiting |
| Moffitt Cancer Center | Tampa | Florida | 33612 | Recruiting |
| Winship Cancer Institute, Emory University | Atlanta | Georgia | 30322 | Recruiting |
| University of Illinois Hospital and Health Sciences System (Outpatient Cancer Center) | Chicago | Illinois | 60612 | Recruiting |
| University of Iowa Health Care | Iowa City | Iowa | 52242 | Recruiting |
| Sidney Kimmel Comprehensive Cancer Center | Baltimore | Maryland | 21287 | Recruiting |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | Recruiting |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | Recruiting |
| START Midwest - Oncology | Grand Rapids | Michigan | 49546 | Recruiting |
| Mayo Clinic | Rochester | Minnesota | 55905 | Recruiting |
| Astera Cancer Care | East Brunswick | New Jersey | 08816 | Recruiting |
| Perlmutter Cancer Center - Sunset Park | Brooklyn | New York | 11220 | Recruiting |
| Perlmutter Cancer Center at NYU Langone Hospital - Long Island | Mineola | New York | 11501 | Recruiting |
| Laura & Isaac Perlmutter Cancer Center at NYU Langone Health | New York | New York | 10016 | Recruiting |
| Providence Cancer Institute Franz Clinic | Portland | Oregon | 97213 | Recruiting |
| SCRI Oncology Partners Group | Nashville | Tennessee | 37203 | Recruiting |
| The University of Texas M.D. Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| START San Antonio, LLC | San Antonio | Texas | 78229 | Recruiting |
| University of Texas Health Science Center San Antonio | San Antonio | Texas | 78229 | Recruiting |
| START Mountain | West Valley City | Utah | 84119 | Recruiting |
| NEXT Virginia | Fairfax | Virginia | 22031 | Recruiting |
| University of Wisconsin Carbone Cancer Center | Madison | Wisconsin | 53792 | Recruiting |
| Froedtert Hospital & the Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06638307, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 11, 2026 · Synced May 16, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06638307 live on ClinicalTrials.gov.