Study to Evaluate Immunogenicity and Safety of a High-Dose Influenza Vaccine in Adults 50 Through 64 Years of Age
Public ClinicalTrials.gov record NCT06641180. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Modified Double-blind, 2-arm Study to Evaluate the Immunogenicity and Safety of High-Dose Inactivated Influenza Vaccine (IIV-HD) Compared With a Standard-dose Inactivated Influenza Vaccine (IIV-SD) in Participants 50 Through 64 Years of Age.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate Immunogenicity and Safety of a High-Dose (HD) Influenza Vaccine (IV) in Adults 50 through 64 Years of Age.
Study identification
- NCT ID
- NCT06641180
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,180 participants
Conditions and interventions
Conditions
Interventions
- High-Dose trivalent influenza vaccine (Split virion, Inactivated) Biological
- Standard-dose trivalent influenza vaccine (Split virion, Inactivated) Biological
Biological
Eligibility (public fields only)
- Age range
- 50 Years to 64 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 3, 2024
- Primary completion
- Jan 27, 2025
- Completion
- Jun 23, 2025
- Last update posted
- Dec 2, 2025
2024 – 2025
United States locations
- U.S. sites
- 20
- U.S. states
- 14
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| CenExel CNS- Site Number : 8400005 | Los Alamitos | California | 90720 | — |
| Alliance for Multispeciality Research - Fort Myers- Site Number : 8400019 | Fort Myers | Florida | 33912 | — |
| Research Centers of America - Hollywood- Site Number : 8400010 | Hollywood | Florida | 33024 | — |
| IACT Health - Columbus - Talbotton Road- Site Number : 8400011 | Columbus | Georgia | 31904 | — |
| Cenexel IRA - iResearch Atlanta- Site Number : 8400007 | Decatur | Georgia | 30030 | — |
| The Hope Clinic of Emory Vaccine Center- Site Number : 8400017 | Decatur | Georgia | 30030 | — |
| Centricity Research - Rincon- Site Number : 8400012 | Rincon | Georgia | 31406 | — |
| Cenexel IRS - iResearch Savannah- Site Number : 8400008 | Savannah | Georgia | 31405 | — |
| Alliance for Multispeciality Research - Newton- Site Number : 8400003 | Newton | Kansas | 67114 | — |
| Alliance for Multispeciality Research - Lexington- Site Number : 8400002 | Lexington | Kentucky | 40509 | — |
| CBH Health - Gaithersburg- Site Number : 8400004 | Gaithersburg | Maryland | 20877 | — |
| Hassman Research Institute - Berlin- Site Number : 8400006 | Berlin | New Jersey | 08009 | — |
| Centricity Morehead- Site Number : 8400014 | Morehead City | North Carolina | 28557 | — |
| Centricity New Bern- Site Number : 8400015 | New Bern | North Carolina | 28562 | — |
| Aventiv Research Columbus- Site Number : 8400016 | Columbus | Ohio | 43213 | — |
| Kaiser Permanente Center for Health Research- Site Number : 8400018 | Portland | Oregon | 97227 | — |
| Alliance for Multispecialty Research - Volunteer Research Group- Site Number : 8400001 | Knoxville | Tennessee | 37920 | — |
| JBR Clinical Research- Site Number : 8400009 | Salt Lake City | Utah | 84107 | — |
| Centricity Research - Suffolk Primary Care - Centricity - PPDS- Site Number : 8400013 | Suffolk | Virginia | 23435-3763 | — |
| Kaiser Permanente Washington- Site Number : 8400024 | Seattle | Washington | 98101 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06641180, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 2, 2025 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06641180 live on ClinicalTrials.gov.