A Study of Suvorexant (MK-4305) for the Treatment of Insomnia Disorder in Participants With Opioid Use Disorder (MK-4305-098)
Public ClinicalTrials.gov record NCT06655883. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Suvorexant for the Treatment of Insomnia in Participants With Opioid Use Disorder
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
People with opioid use disorder (OUD) can have trouble falling or staying asleep. Researchers want to know if suvorexant will help people with OUD fall asleep and stay asleep. The goal of this study is to learn about the safety of suvorexant and how well people tolerate it. Researchers also want to learn if suvorexant helps people sleep longer compared to people who take placebo. A placebo looks like the study medicine but has no actual study medicine in it.
Study identification
- NCT ID
- NCT06655883
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 300 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 8, 2025
- Primary completion
- Jun 23, 2027
- Completion
- Jun 23, 2027
- Last update posted
- Aug 27, 2026
2025 – 2027
United States locations
- U.S. sites
- 13
- U.S. states
- 12
- U.S. cities
- 13
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cenexel CNS ( Site 2012) | Garden Grove | California | 92845 | Recruiting |
| Yale University School of Medicine ( Site 1003) | New Haven | Connecticut | 06520 | Recruiting |
| Bradenton Research Center ( Site 2021) | Bradenton | Florida | 34205 | Recruiting |
| CenExel iResearch, LLC ( Site 2010) | Savannah | Georgia | 31405 | Recruiting |
| Johns Hopkins University ( Site 1001) | Baltimore | Maryland | 21224 | Recruiting |
| Hassman Research Institute Marlton Site ( Site 2005) | Marlton | New Jersey | 08053 | Recruiting |
| The Rivus Wellness & Research Institute ( Site 2014) | Oklahoma City | Oklahoma | 73112 | Recruiting |
| Penn Medicine University of Pennsylvania Health System- Center for Studies of Addiction ( Site 1006) | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Butler Hospital ( Site 1002) | Providence | Rhode Island | 02906 | Recruiting |
| Medical University of South Carolina ( Site 1005) | Charleston | South Carolina | 29403 | Recruiting |
| Adams Clinical Dallas ( Site 2007) | DeSoto | Texas | 75115 | Recruiting |
| Memorial Hermann Village ( Site 2001) | Houston | Texas | 77043 | Recruiting |
| VCU Institute for Drug and Alcohol Studies ( Site 1004) | Richmond | Virginia | 23219 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06655883, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 27, 2026 · Synced Sep 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06655883 live on ClinicalTrials.gov.