Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
ClinicalTrials.gov record
Recruiting Phase 2 Interventional

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

ClinicalTrials.gov ID: NCT06680830

Public ClinicalTrials.gov record NCT06680830. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

View official ClinicalTrials.gov record → Back to search
ClinicalTrials.gov public records Last synced Sep 21, 2026, 11:06 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study and Open-Label Extension to Evaluate the Safety and Efficacy of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease (NEULARK)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The goal of this Phase 2 clinical trial is to investigate the efficacy and safety of NEU-411 in men and women aged 40-80 years with early Parkinson's Disease (PD) who have predicted elevations in the activity of the "leucine-rich repeat kinase 2" ("LRRK2" for short) pathway based on their genetic profile. A DNA test will be used to identify the "LRRK2-driven" population with predicted elevation in the LRRK2 pathway.

Study identification

NCT ID
NCT06680830
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Neuron23 Inc.
Industry
Enrollment
150 participants

Conditions and interventions

Interventions

Drug · Other

Eligibility (public fields only)

Age range
40 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 16, 2025
Primary completion
Nov 30, 2027
Completion
May 31, 2028
Last update posted
Aug 27, 2026

2025 – 2028

United States locations

U.S. sites
45
U.S. states
29
U.S. cities
43
Facility City State ZIP Site status
Banner Sun Health Research Institute Sun City Arizona 85351 Recruiting
University of Arkansas Little Rock Arkansas 72205 Recruiting
Neuro-Pain Medical Center Fresno California 93710 Recruiting
University of California, Irvine Irvine California 92697 Recruiting
University of California, Los Angeles Los Angeles California 90095 Recruiting
Esperanza Clinical Murrieta California 92562 Recruiting
Parkinson's Research Centers of America - Palo Alto Palo Alto California 94301 Recruiting
Sutter Neuroscience Institute Sacramento California 95816 Recruiting
University of Colorado - Anschutz Medical Campus Aurora Colorado 80045 Recruiting
Parkinson's Disease and Movement Disorders Center of Boca Raton Boca Raton Florida 33486 Recruiting
University of Florida Gainesville Florida 32608 Recruiting
Neurology One Orlando Florida 32825 Recruiting
USF Parkinson's & Movement Disorders Clinic Tampa Florida 33613 Recruiting
Emory University Atlanta Georgia 30329 Recruiting
Augusta University Augusta Georgia 30912 Recruiting
Northwestern Medical Group, Department of Neurology Chicago Illinois 60611 Recruiting
University of Kansas Medical Center Kansas City Kansas 66160 Recruiting
University of Kentucky Lexington Kentucky 40536 Recruiting
Ochsner Clinic Foundation New Orleans Louisiana 70121 Recruiting
University of Maryland Baltimore Maryland 21201 Recruiting
Beth Israel Deaconess Medical Center Boston Massachusetts 02215 Recruiting
Quest Research Institute Farmington Hills Michigan 48334 Recruiting
Struthers Parkinson Center Golden Valley Minnesota 55427 Recruiting
Cleveland Clinic Las Vegas Nevada 89106 Recruiting
University of New Mexico Albuquerque New Mexico 87106 Recruiting
Northwell Health Manhasset New York 11030 Recruiting
Icahn School of Medicine at Mount Sinai/Mount Sinai West New York New York 10019 Recruiting
Columbia University New York New York 10032 Recruiting
University of Rochester Rochester New York 14618 Recruiting
University of North Carolina - Chapel Hill Chapel Hill North Carolina 27599 Recruiting
The Ohio State University Columbus Ohio 43210 Recruiting
The Movement Disorder Clinic of Oklahoma Tulsa Oklahoma 74136 Recruiting
Oregon Health & Science University (OHSU) Portland Oregon 97239 Recruiting
Thomas Jefferson University Hospital Philadelphia Pennsylvania 19107 Recruiting
Medical University of South Carolina Charleston South Carolina 29425 Recruiting
Vanderbilt University Nashville Tennessee 37232 Recruiting
Neurology Consultants of Dallas PA Dallas Texas 75243 Recruiting
Baylor College of Medicine Houston Texas 77030 Recruiting
The University of Texas Health Science Center at Houston Houston Texas 77030 Recruiting
Central Texas Neurology Consultants Round Rock Texas 78681 Recruiting
University of Utah Movement Division Salt Lake City Utah 84108 Recruiting
University of Virginia Charlottesville Virginia 22903 Recruiting
EvergreenHealth Kirkland Washington 98034 Recruiting
Inland Northwest Research Spokane Washington 99202 Recruiting
Medical College of Wisconsin Milwaukee Wisconsin 53226 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 27 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06680830, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 27, 2026 · Synced Sep 21, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06680830 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →