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Active, not recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Study of a Human Metapneumovirus/Respiratory Syncytial Virus mRNA Vaccine Candidate Encapsulated in a Lipid Nanoparticle-based Formulation in Adults Aged 60 Years and Older

ClinicalTrials.gov ID: NCT06686654

Public ClinicalTrials.gov record NCT06686654. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 10:20 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1/2, Randomized, Observer-blind, Placebo-controlled Multi-arm Study to Evaluate the Safety and Immunogenicity of an hMPV/RSV mRNA Vaccine Candidate in Adult Participants Aged 60 Years and Older

Study identification

NCT ID
NCT06686654
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Sanofi Pasteur, a Sanofi Company
Industry
Enrollment
1,530 participants

Conditions and interventions

Interventions

  • Investigational hMPV/RSV vaccine Biological
  • Investigational hMPV vaccine (monovalent) Biological
  • Investigational RSV vaccine (monovalent) Biological
  • Licensed RSV Vaccine Biological
  • Placebo Biological
  • Investigational RSV+hMPV vaccine Biological

Biological

Eligibility (public fields only)

Age range
60 Years and older
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 10, 2024
Primary completion
Jan 17, 2027
Completion
Jan 17, 2027
Last update posted
Dec 10, 2025

2024 – 2027

United States locations

U.S. sites
24
U.S. states
15
U.S. cities
23
Facility City State ZIP Site status
Velocity Clinical Research, Phoenix- Site Number : 8400025 Phoenix Arizona 85006
CenExel CNS-Garden Grove- Site Number : 8400017 Garden Grove California 92845
National Research Institute - Gardena- Site Number : 8400005 Gardena California 90247
National Research Institute - Huntington Park- Site Number : 8400014 Huntington Park California 90255
Velocity Clinical Research - San Diego- Site Number : 8400008 La Mesa California 91942
Velocity Clinical Research Los Angeles- Site Number : 8400013 Los Angeles California 90017
National Research Institute - Panorama City- Site Number : 8400012 Los Angeles California 91402
Providence Clinical Research - North Hollywood- Site Number : 8400018 North Hollywood California 91606
Peninsula Research Associates- Site Number : 8400002 Rolling Hills Estates California 90274
Velocity Clinical Research - Denver- Site Number : 8400016 Englewood Colorado 80110
Velocity Clinical Research - Washington DC- Site Number : 8400007 Washington D.C. District of Columbia 20016
Velocity Clinical Research - Hallandale Beach- Site Number : 8400022 Hallandale Florida 33009
Suncoast Research Associates - Miami - Sunset Drive- Site Number : 8400001 Miami Florida 33173
Velocity Clinical Research - Meridian- Site Number : 8400003 Meridian Idaho 83642
Velocity Clinical Research - Kansas City- Site Number : 8400015 Overland Park Kansas 66210
Velocity Clinical Research - Rockville- Site Number : 8400011 Rockville Maryland 20854
Velocity Clinical Research - Lincoln - Valley Road- Site Number : 8400023 Lincoln Nebraska 68510
Velocity Clinical Research - Omaha- Site Number : 8400006 Omaha Nebraska 68134
Velocity Clinical Research - Springdale- Site Number : 8400004 Cincinnati Ohio 45246
Velocity Clinical Research - Medford- Site Number : 8400024 Medford Oregon 97504
Velocity Clinical Research - Austin- Site Number : 8400020 Cedar Park Texas 78613
Velocity Clinical Research - Salt Lake City- Site Number : 8400010 West Jordan Utah 84088
Velocity Clinical Research - Hampton- Site Number : 8400026 Hampton Virginia 23666
Velocity Clinical Research - Seattle- Site Number : 8400019 Seattle Washington 98105

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06686654, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 10, 2025 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06686654 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →