Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

ClinicalTrials.gov ID: NCT06686771

Public ClinicalTrials.gov record NCT06686771. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 5, 2026, 3:17 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Consolidative Use of Radiotherapy to Block (CURB2) Oligoprogression In Patients With Metastatic Non-Small-Cell Lung Cancer

Study identification

NCT ID: NCT06686771
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Canadian Cancer Trials Group; Network
Enrollment: 320 participants

Conditions and interventions

Conditions

Non-small Cell Lung Cancer

Interventions

First or second-line standard of care therapy Other
SBRT Radiation

Other · Radiation

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Dec 15, 2025
Primary completion: Feb 27, 2030
Completion: Dec 30, 2030
Last update posted: Apr 13, 2026

2025 – 2030

United States locations

U.S. sites: 54
U.S. states: 15
U.S. cities: 45

Facility	City	State	ZIP	Site status
City of Hope Comprehensive Cancer Center	Duarte	California	91010	Recruiting
City of Hope at Irvine Lennar	Irvine	California	92618	Recruiting
Saint Mary's Hospital and Regional Medical Center	Grand Junction	Colorado	81501	Recruiting
Saint Luke's Cancer Institute - Boise	Boise	Idaho	83712	Recruiting
Saint Luke's Cancer Institute - Fruitland	Fruitland	Idaho	83619	Recruiting
Saint Luke's Cancer Institute - Meridian	Meridian	Idaho	83642	Recruiting
Saint Luke's Cancer Institute - Nampa	Nampa	Idaho	83687	Recruiting
Alton Memorial Hospital	Alton	Illinois	62002	Recruiting
Northwestern University	Chicago	Illinois	60611	Recruiting
Northwestern Medicine Cancer Center Kishwaukee	DeKalb	Illinois	60115	Recruiting
Decatur Memorial Hospital	Decatur	Illinois	62526	Recruiting
Crossroads Cancer Center	Effingham	Illinois	62401	Recruiting
Northwestern Medicine Cancer Center Delnor	Geneva	Illinois	60134	Recruiting
Northwestern Medicine Glenview Outpatient Center	Glenview	Illinois	60026	Recruiting
Northwestern Medicine Grayslake Outpatient Center	Grayslake	Illinois	60030	Recruiting
Northwestern Medicine Lake Forest Hospital	Lake Forest	Illinois	60045	Recruiting
HSHS Saint Elizabeth's Hospital	O'Fallon	Illinois	62269	Recruiting
Northwestern Medicine Oak Brook	Oak Brook	Illinois	60523	Recruiting
Northwestern Medicine Orland Park	Orland Park	Illinois	60462	Recruiting
Memorial Hospital East	Shiloh	Illinois	62269	Recruiting
Northwestern Medicine Cancer Center Warrenville	Warrenville	Illinois	60555	Recruiting
Mercy Hospital	Cedar Rapids	Iowa	52403	Recruiting
Oncology Associates at Mercy Medical Center	Cedar Rapids	Iowa	52403	Recruiting
Miller-Dwan Hospital	Duluth	Minnesota	55805	Recruiting
Coborn Cancer Center at Saint Cloud Hospital	Saint Cloud	Minnesota	56303	Recruiting
Saint Francis Medical Center	Cape Girardeau	Missouri	63703	Recruiting
Siteman Cancer Center at Saint Peters Hospital	City of Saint Peters	Missouri	63376	Recruiting
Siteman Cancer Center at West County Hospital	Creve Coeur	Missouri	63141	Recruiting
Washington University School of Medicine	St Louis	Missouri	63110	Recruiting
Siteman Cancer Center-South County	St Louis	Missouri	63129	Recruiting
Siteman Cancer Center at Christian Hospital	St Louis	Missouri	63136	Recruiting
Nebraska Medicine-Bellevue	Bellevue	Nebraska	68123	Recruiting
Nebraska Medicine-Village Pointe	Omaha	Nebraska	68118	Recruiting
University of Nebraska Medical Center	Omaha	Nebraska	68198	Recruiting
Northwell Health/Center for Advanced Medicine	Lake Success	New York	11042	Recruiting
Mount Sinai Chelsea	New York	New York	10011	Recruiting
Mount Sinai West	New York	New York	10019	Recruiting
Mount Sinai Hospital	New York	New York	10029	Recruiting
Manhattan Eye Ear and Throat Hospital	New York	New York	10065	Recruiting
Lenox Hill Hospital	New York	New York	10075	Recruiting
Queens Cancer Center	Rego Park	New York	11374	Recruiting
State University of New York Upstate Medical University	Syracuse	New York	13210	Recruiting
University of Oklahoma Health Sciences Center	Oklahoma City	Oklahoma	73104	Recruiting
Geisinger Medical Center	Danville	Pennsylvania	17822	Recruiting
Penn State Milton S Hershey Medical Center	Hershey	Pennsylvania	17033-0850	Recruiting
Geisinger Medical Oncology-Lewisburg	Lewisburg	Pennsylvania	17837	Recruiting
Thomas Jefferson University Hospital	Philadelphia	Pennsylvania	19107	Recruiting
UPMC-Shadyside Hospital	Pittsburgh	Pennsylvania	15232	Recruiting
Geisinger Wyoming Valley/Henry Cancer Center	Wilkes-Barre	Pennsylvania	18711	Recruiting
Vanderbilt University/Ingram Cancer Center	Nashville	Tennessee	37232	Recruiting
The Don and Sybil Harrington Cancer Center	Amarillo	Texas	79106	Recruiting
VCU Massey Cancer Center at Stony Point	Richmond	Virginia	23235	Recruiting
VCU Massey Comprehensive Cancer Center	Richmond	Virginia	23298	Recruiting
Northwest Wisconsin Cancer Center	Ashland	Wisconsin	54806	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06686771, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 13, 2026 · Synced May 5, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06686771 live on ClinicalTrials.gov.

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