A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

ClinicalTrials.gov ID: NCT06692738

Public ClinicalTrials.gov record NCT06692738. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 6, 2026, 8:54 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Randomized, Double-blind, Multicenter, Global Study of Rilvegostomig or Pembrolizumab in Combination With Platinum-based Chemotherapy for the First-line Treatment of Patients With Metastatic Squamous Non-small Cell Lung Cancer Whose Tumors Express PD-L1 (ARTEMIDE-Lung02)

Study identification

NCT ID: NCT06692738
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: AstraZeneca; Industry
Enrollment: 880 participants

Conditions and interventions

Conditions

Non-small Cell Lung Cancer

Interventions

Carboplatin Drug
Nab-paclitaxel Drug
Paclitaxel Drug
Pembrolizumab Drug
Rilvegostomig Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Nov 17, 2024
Primary completion: Feb 4, 2029
Completion: Oct 7, 2029
Last update posted: Apr 30, 2026

2024 – 2029

United States locations

U.S. sites: 73
U.S. states: 29
U.S. cities: 69

Facility	City	State	ZIP	Site status
Research Site	Tucson	Arizona	85724	Recruiting
Research Site	Springdale	Arkansas	72762	Recruiting
Research Site	Anaheim	California	92801	Recruiting
Research Site	Beverly Hills	California	90211	Recruiting
Research Site	Loma Linda	California	92354	Recruiting
Research Site	Los Alamitos	California	90720	Recruiting
Research Site	Redlands	California	92373	Recruiting
Research Site	San Francisco	California	94121	Recruiting
Research Site	Walnut Creek	California	94598	Recruiting
Research Site	West Haven	Connecticut	06516	Recruiting
Research Site	Newark	Delaware	19713	Recruiting
Research Site	Bay Pines	Florida	33744	Recruiting
Research Site	Fort Lauderdale	Florida	33308	Recruiting
Research Site	Gainesville	Florida	32608	Recruiting
Research Site	Gainesville	Florida	32610	Withdrawn
Research Site	Jacksonville	Florida	32224	Recruiting
Research Site	Athens	Georgia	30607	Recruiting
Research Site	Atlanta	Georgia	30341	Withdrawn
Research Site	Boise	Idaho	83712	Recruiting
Research Site	Chicago	Illinois	60637	Recruiting
Research Site	Decatur	Illinois	62526	Recruiting
Research Site	Hinsdale	Illinois	60521	Recruiting
Research Site	Quincy	Illinois	62301	Recruiting
Research Site	Rockford	Illinois	61114	Not yet recruiting
Research Site	Waterloo	Iowa	50702	Recruiting
Research Site	Lexington	Kentucky	40509	Recruiting
Research Site	Lexington	Kentucky	40536	Withdrawn
Research Site	Louisville	Kentucky	40202	Recruiting
Research Site	Louisville	Kentucky	40207	Recruiting
Research Site	Alexandria	Louisiana	71301	Withdrawn
Research Site	Baton Rouge	Louisiana	70808	Recruiting
Research Site	Covington	Louisiana	70433	Withdrawn
Research Site	Shreveport	Louisiana	71103	Recruiting
Research Site	Shreveport	Louisiana	71105	Recruiting
Research Site	South Portland	Maine	04106	Recruiting
Research Site	Baltimore	Maryland	21202	Recruiting
Research Site	Bethesda	Maryland	20817	Recruiting
Research Site	Detroit	Michigan	48202	Recruiting
Research Site	Grand Rapids	Michigan	49503	Recruiting
Research Site	Duluth	Minnesota	55802	Recruiting
Research Site	Rochester	Minnesota	55905	Recruiting
Research Site	Bridgeton	Missouri	63044	Recruiting
Research Site	Columbia	Missouri	65212	Withdrawn
Research Site	Kansas City	Missouri	64108	Recruiting
Research Site	Lincoln	Nebraska	68506	Recruiting
Research Site	Camden	New Jersey	08103	Recruiting
Research Site	Buffalo	New York	14221	Recruiting
Research Site	East Syracuse	New York	13057	Recruiting
Research Site	Westbury	New York	11590	Recruiting
Research Site	Grand Forks	North Dakota	58201	Recruiting
Research Site	Canton	Ohio	44718	Not yet recruiting
Research Site	Cincinnati	Ohio	45267	Recruiting
Research Site	Bend	Oregon	97701	Withdrawn
Research Site	Medford	Oregon	97504	Recruiting
Research Site	Salem	Oregon	97301	Recruiting
Research Site	Hershey	Pennsylvania	17033	Recruiting
Research Site	York	Pennsylvania	17403	Recruiting
Research Site	Sioux Falls	South Dakota	57105	Recruiting
Research Site	Chattanooga	Tennessee	37404	Recruiting
Research Site	Nashville	Tennessee	37203	Recruiting
Research Site	Fort Worth	Texas	76104	Recruiting
Research Site	Houston	Texas	77090	Completed
Research Site	Kingwood	Texas	77339	Recruiting
Research Site	Lubbock	Texas	79410	Recruiting
Research Site	Round Rock	Texas	78665	Recruiting
Research Site	Fairfax	Virginia	22031	Recruiting
Research Site	Fredericksburg	Virginia	22408	Recruiting
Research Site	Olympia	Washington	98506	Recruiting
Research Site	Seattle	Washington	98101	Recruiting
Research Site	Silverdale	Washington	98383	Withdrawn
Research Site	Spokane	Washington	99208	Recruiting
Research Site	Tacoma	Washington	98405	Recruiting
Research Site	Wenatchee	Washington	98801	Withdrawn

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 228 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06692738, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 30, 2026 · Synced May 6, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06692738 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →