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Recruiting Phase 3 Interventional

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

ClinicalTrials.gov ID: NCT06692738

Public ClinicalTrials.gov record NCT06692738. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Sep 2, 2026, 3:56 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Randomized, Double-blind, Multicenter, Global Study of Rilvegostomig or Pembrolizumab in Combination With Platinum-based Chemotherapy for the First-line Treatment of Patients With Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer Whose Tumors Express PD-L1 (ARTEMIDE-Lung02)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of ARTEMIDE-Lung02 is to assess the efficacy and safety of rilvegostomig in combination with platinum-based chemotherapy for the first-line (1L) treatment of patients with locally advanced or metastatic squamous non-small cell lung cancer (mNSCLC) whose tumors express programmed death-ligand 1 (PD-L1).

Study identification

NCT ID
NCT06692738
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
AstraZeneca
Industry
Enrollment
1,160 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 17, 2024
Primary completion
Jun 30, 2030
Completion
Jun 30, 2030
Last update posted
Aug 12, 2026

2024 – 2030

United States locations

U.S. sites
77
U.S. states
31
U.S. cities
72
Facility City State ZIP Site status
Research Site Tucson Arizona 85724 Recruiting
Research Site Springdale Arkansas 72762 Recruiting
Research Site Anaheim California 92801 Recruiting
Research Site Beverly Hills California 90211 Recruiting
Research Site Loma Linda California 92354 Recruiting
Research Site Los Alamitos California 90720 Recruiting
Research Site Redlands California 92373 Recruiting
Research Site San Francisco California 94121 Recruiting
Research Site Walnut Creek California 94598 Recruiting
Research Site West Haven Connecticut 06516 Recruiting
Research Site Newark Delaware 19713 Recruiting
Research Site Bay Pines Florida 33744 Recruiting
Research Site Fort Lauderdale Florida 33308 Recruiting
Research Site Gainesville Florida 32608 Recruiting
Research Site Gainesville Florida 32610 Withdrawn
Research Site Jacksonville Florida 32224 Recruiting
Research Site Athens Georgia 30607 Recruiting
Research Site Atlanta Georgia 30341 Withdrawn
Research Site Savannah Georgia 31404 Not yet recruiting
Research Site Boise Idaho 83712 Recruiting
Research Site Chicago Illinois 60637 Recruiting
Research Site Decatur Illinois 62526 Recruiting
Research Site Hinsdale Illinois 60521 Recruiting
Research Site Quincy Illinois 62301 Recruiting
Research Site Rockford Illinois 61114 Withdrawn
Research Site Fort Wayne Indiana 46845 Not yet recruiting
Research Site Waterloo Iowa 50702 Recruiting
Research Site Lexington Kentucky 40509 Recruiting
Research Site Lexington Kentucky 40536 Withdrawn
Research Site Louisville Kentucky 40202 Recruiting
Research Site Louisville Kentucky 40207 Recruiting
Research Site Alexandria Louisiana 71301 Withdrawn
Research Site Baton Rouge Louisiana 70808 Recruiting
Research Site Covington Louisiana 70433 Withdrawn
Research Site Shreveport Louisiana 71103 Recruiting
Research Site Shreveport Louisiana 71105 Recruiting
Research Site Scarborough Maine 04074 Recruiting
Research Site Baltimore Maryland 21202 Completed
Research Site Bethesda Maryland 20817 Recruiting
Research Site Bethesda Maryland 20889 Not yet recruiting
Research Site Detroit Michigan 48202 Recruiting
Research Site Grand Rapids Michigan 49503 Recruiting
Research Site Saginaw Michigan 48602 Not yet recruiting
Research Site Duluth Minnesota 55802 Recruiting
Research Site Rochester Minnesota 55905 Recruiting
Research Site Bridgeton Missouri 63044 Recruiting
Research Site Columbia Missouri 65212 Withdrawn
Research Site Kansas City Missouri 64108 Recruiting
Research Site Lincoln Nebraska 68506 Recruiting
Research Site Camden New Jersey 08103 Recruiting
Research Site Buffalo New York 14221 Recruiting
Research Site East Syracuse New York 13057 Recruiting
Research Site Westbury New York 11590 Recruiting
Research Site Wilson North Carolina 27893 Recruiting
Research Site Grand Forks North Dakota 58201 Recruiting
Research Site Cincinnati Ohio 45267 Recruiting
Research Site Bend Oregon 97701 Withdrawn
Research Site Medford Oregon 97504 Recruiting
Research Site Salem Oregon 97301 Recruiting
Research Site Hershey Pennsylvania 17033 Recruiting
Research Site York Pennsylvania 17403 Recruiting
Research Site Sioux Falls South Dakota 57105 Recruiting
Research Site Chattanooga Tennessee 37404 Recruiting
Research Site Nashville Tennessee 37203 Recruiting
Research Site Fort Worth Texas 76104 Recruiting
Research Site Houston Texas 77090 Completed
Research Site Kingwood Texas 77339 Recruiting
Research Site Lubbock Texas 79410 Recruiting
Research Site Round Rock Texas 78665 Recruiting
Research Site Fairfax Virginia 22031 Recruiting
Research Site Fredericksburg Virginia 22408 Recruiting
Research Site Olympia Washington 98506 Recruiting
Research Site Seattle Washington 98101 Recruiting
Research Site Silverdale Washington 98383 Withdrawn
Research Site Spokane Washington 99208 Recruiting
Research Site Tacoma Washington 98405 Recruiting
Research Site Wenatchee Washington 98801 Withdrawn

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 248 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06692738, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 12, 2026 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06692738 live on ClinicalTrials.gov.

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