Light-Activated Antimicrobial Therapy to Prevent Surgical Site Infections
Public ClinicalTrials.gov record NCT06702878. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Group-Randomized, Standard-of-Care-Controlled, Crossover Trial Evaluating Nasal Antimicrobial Photodisinfection for the Prevention of Surgical Site Infections
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 3 multi-center, group-randomized, crossover trial to compare nasal antimicrobial photodisinfection therapy (aPDT) with standard of care for prevention of surgical site infections in patients undergoing major elective, urgent, or emergent surgeries in a hospital setting. The main outcomes are to: 1. compare the efficacy, and 2. estimate the safety of applying nasal (aPDT) before surgery in reducing the incidence of SSIs within the initial 30 days after surgery compared to standard of care (SOC). Participants in the intervention group will receive aPDT prior to surgery on the day of surgery. Participants in the control group will receive standard of care surgical site prevention measures prior to surgery.
Study identification
- NCT ID
- NCT06702878
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 4,787 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 26, 2024
- Primary completion
- Apr 2, 2026
- Completion
- May 6, 2026
- Last update posted
- May 11, 2026
2024 – 2026
United States locations
- U.S. sites
- 14
- U.S. states
- 5
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Swedish Medical Center | Englewood | Colorado | 80113 | — |
| HCA Brandon Florida | Brandon | Florida | 33511 | — |
| HCA Florida Largo Hospital | Largo | Florida | 33770 | — |
| HCA Florida NorthSide Hospital | St. Petersburg | Florida | 33709 | — |
| HCA Florida Trinity Hospital | Trinity | Florida | 34655 | — |
| Centennial Medical Center | Nashville | Tennessee | 37203 | — |
| Medical City Frisco Hospital | Frisco | Texas | 75034 | — |
| HCA Houston Healthcare Kingwood | Kingwood | Texas | 77339 | — |
| Medical City Plano | Plano | Texas | 75075 | — |
| Methodist Metropolitan Hospital | San Antonio | Texas | 78212 | — |
| Methodist Main Hospital and Landmark | San Antonio | Texas | 78229 | — |
| Methodist Stone Oak | San Antonio | Texas | 78258 | — |
| HCA Houston Healthcare Clear Lake Hospital | Webster | Texas | 77598 | — |
| Johnston Willis Hospital | Richmond | Virginia | 23235 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06702878, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 11, 2026 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06702878 live on ClinicalTrials.gov.